Patents by Inventor Timothy Joseph KEANE Jr.

Timothy Joseph KEANE Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200360565
    Abstract: Provided are methods for preparing non-gelling, solubilized extracellular matrix (ECM) materials useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the non-gelling, solubilized ECM composition is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient. In another embodiment, the composition is delivered intraarticularly, intrathecally, intraoccularly, intracranially, and into pleural space.
    Type: Application
    Filed: August 6, 2020
    Publication date: November 19, 2020
    Inventors: Stephen F. Badylak, Timothy Joseph Keane, JR., Lisa Jane White
  • Patent number: 10736991
    Abstract: Provided are methods for preparing non-gelling, solubilized extracellular matrix (ECM) materials useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the non-gelling, solubilized ECM composition is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient. In another embodiment, the composition is delivered intraarticularly, intrathecally, intraoccularly, intracranially, and into pleural space.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: August 11, 2020
    Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, The University of Nottingham
    Inventors: Stephen F. Badylak, Timothy Joseph Keane, Jr., Lisa Jane White
  • Publication number: 20190374683
    Abstract: Provided are methods for preparing sterilized, gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
    Type: Application
    Filed: January 3, 2019
    Publication date: December 12, 2019
    Inventors: Stephen F. Badylak, Christopher Lee Dearth, Timothy Joseph Keane, JR., Neill Jordon Turner
  • Publication number: 20190060521
    Abstract: Provided are methods for preparing non-gelling, solubilized extracellular matrix (ECM) materials useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the non-gelling, solubilized ECM composition is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient. In another embodiment, the composition is delivered intraarticularly, intrathecally, intraoccularly, intracranially, and into pleural space.
    Type: Application
    Filed: September 16, 2016
    Publication date: February 28, 2019
    Inventors: Stephen F. Badylak, Timothy Joseph Keane, Jr., Lisa Jane White
  • Patent number: 10213526
    Abstract: Provided are methods for preparing sterilized, gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: February 26, 2019
    Assignee: University of Pittsburgh-Of the Commonwealth System of Higher Education
    Inventors: Stephen F. Badylak, Christopher Lee Dearth, Timothy Joseph Keane, Jr., Neill Jordon Turner
  • Publication number: 20180200405
    Abstract: Provided herein is a method for producing decellularized colonic extracellular matrix material. A decellularized colonic extracellular matrix material also is provided, along with uses for the material. Methods of use of the decellularized colonic extracellular matrix material also are provided, including methods of treating a defective, diseased, or damaged tissue or organ in a patient, and/or methods of treating esophageal disease, short bowel syndrome, ulcerative colitis, Crohn's disease, or mucositis in a patient.
    Type: Application
    Filed: July 8, 2016
    Publication date: July 19, 2018
    Inventors: Stephen F. Badylak, Timothy Joseph Keane, Jr.
  • Publication number: 20170173217
    Abstract: Provided are methods for preparing sterilized, gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
    Type: Application
    Filed: March 20, 2015
    Publication date: June 22, 2017
    Inventors: Stephen F. BADYLAK, Christopher Lee DEARTH, Timothy Joseph KEANE Jr., Neill Jordon TURNER