Patents by Inventor Timothy Kern

Timothy Kern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of treating diabetic retinopathy
    Patent number: 10898516
    Abstract: A method of treating diabetic retinopathy in a subject in need thereof includes administering to the subject a therapeutically effective amount of one or more agents that act as a trap of reactive aldehydes and/or inhibit diabetes-induced superoxide generation and capillary degeneration regulated by GPCR signaling pathways.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: January 26, 2021
    Assignee: CASE WESTERN UNIVERSITY
    Inventors: Krzysztof Palczewski, Timothy Kern
  • COMPOSITIONS AND METHODS OF PROMOTING WOUND HEALING
    Publication number: 20200062855
    Abstract: A method of promoting wound healing and/or treating wounds in a subject in need thereof includes administering to cells proximate or about the periphery of the wound at least one agent that enhances C3aR and/or C5aR signaling of the cells.
    Type: Application
    Filed: October 22, 2019
    Publication date: February 27, 2020
    Inventors: M. Edward Medof, Timothy Kern, Lorna Kang, Maryo Kohen, Faruk Orge
  • COMPOSITIONS AND METHODS OF TREATING DIABETIC RETINOPATHY
    Publication number: 20190255102
    Abstract: A method of treating diabetic retinopathy in a subject in need thereof includes administering to the subject a therapeutically effective amount of one or more agents that act as a trap of reactive aldehydes and/or inhibit diabetes-induced superoxide generation and capillary degeneration regulated by GPCR signaling pathways.
    Type: Application
    Filed: April 30, 2019
    Publication date: August 22, 2019
    Inventors: Krzysztof Palczewski, Timothy Kern
  • Compositions and methods of treating diabetic retinopathy
    Patent number: 10272106
    Abstract: A method of treating diabetic retinopathy in a subject in need thereof includes administering to the subject a therapeutically effective amount of one or more agents that act as a trap of reactive aldehydes and/or inhibit diabetes-induced superoxide generation and capillary degeneration regulated by GPCR signaling pathways.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: April 30, 2019
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Krzysztof Palczewski, Timothy Kern
  • COMPOSITIONS AND METHODS OF TREATING DIABETIC RETINOPATHY
    Publication number: 20170196908
    Abstract: A method of treating diabetic retinopathy in a subject in need thereof includes administering to the subject a therapeutically effective amount of one or more agents that act as a trap of reactive aldehydes and/or inhibit diabetes-induced superoxide generation and capillary degeneration regulated by GPCR signaling pathways.
    Type: Application
    Filed: June 4, 2015
    Publication date: July 13, 2017
    Inventors: Krzysztof Palczewski, Timothy Kern
  • COMPOSITION AND METHOD OF TREATING PERIPHERAL NEUROPATHY
    Publication number: 20070244077
    Abstract: A method of treating diabetic neuropathy in a subject includes administering to a subject having diabetes or at risk of diabetes a therapeutically effective amount of a pharmaceutical composition comprising at least one of sulfasalazine or a composition including 5-aminosalicyclic acid and sulfapyridine.
    Type: Application
    Filed: March 13, 2007
    Publication date: October 18, 2007
    Inventors: Liliana Berti-Mattera, Timothy Kern
  • Pencil sharpener
    Publication number: 20070062049
    Abstract: An improved pencil sharpener assembly is provided for construction applications. The pencil sharpener assembly includes a retaining clip coupled to a pencil sharpener which discharges shavings outside and away from the housing of the pencil sharpener as a pencil is being sharpened. The retaining clip allows the sharpener assembly to be releasably coupled to a belt, a pocket, a toolbox or other item to allow one-handed use of the pencil sharpener. The pencil sharpener preferably directs shavings out of and away from the sharpener assembly to reduce cost, maintenance and weight, and to eliminate time associated with cleaning or emptying a pencil sharpener.
    Type: Application
    Filed: September 19, 2005
    Publication date: March 22, 2007
    Inventor: Timothy Kern