Patents by Inventor Timothy L. Frankel

Timothy L. Frankel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • T cell receptors and related materials and methods of use
    Patent number: 9688739
    Abstract: The invention provides T cell receptors (TCRs) having antigenic specificity for a cancer antigen, e.g., tyrosinase. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host using the inventive TCRs or related materials.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: June 27, 2017
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Steven A. Rosenberg, Richard A. Morgan, Timothy L. Frankel
  • T CELL RECEPTORS AND RELATED MATERIALS AND METHODS OF USE
    Publication number: 20140206620
    Abstract: The invention provides T cell receptors (TCRs) having antigenic specificity for a cancer antigen, e.g., tyrosinase. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host using the inventive TCRs or related materials.
    Type: Application
    Filed: March 21, 2014
    Publication date: July 24, 2014
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Steven A. Rosenberg, Richard A. Morgan, Timothy L. Frankel
  • T cell receptors and related materials and methods of use
    Patent number: 8785601
    Abstract: The invention provides T cell receptors (TCRs) having antigenic specificity for a cancer antigen, e.g., tyrosinase. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host using the inventive TCRs or related materials.
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: July 22, 2014
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Steven A. Rosenberg, Richard A. Morgan, Timothy L. Frankel, Peter Peng
  • T CELL RECEPTORS AND RELATED MATERIALS AND METHODS OF USE
    Publication number: 20120015888
    Abstract: The invention provides T cell receptors (TCRs) having antigenic specificity for a cancer antigen, e.g., tyrosinase. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host using the inventive TCRs or related materials.
    Type: Application
    Filed: January 25, 2010
    Publication date: January 19, 2012
    Inventors: Steven A. Rosenberg, Richard A. Morgan, Timothy L. Frankel, Peter Peng