Patents by Inventor Timothy Leaf

Timothy Leaf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations
    Patent number: 7648976
    Abstract: Polymorphs and pharmaceutical formulations of 17-allylamino-17-demethoxygeldanamycin (17-AAG).
    Type: Grant
    Filed: November 8, 2006
    Date of Patent: January 19, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Peter J. Licari, Timothy Leaf, Ruchir P. Desai, Jorge L. Galazzo, Greg O. Buchanan, Stephen William Watt, Alexander Redvers Eberlin, Robert Arslanian
  • 17-ALLYLAMINO-17-DEMETHOXYGELDANAMYCIN POLYMORPHS AND FORMULATIONS
    Publication number: 20090042847
    Abstract: Polymorphs and pharmaceutical formulations of 17-allylamino-17-demethoxy-geldanamycin (17-AAG).
    Type: Application
    Filed: May 29, 2008
    Publication date: February 12, 2009
    Applicant: Kosan Biosciences Incorporated
    Inventors: Peter J. Licari, Timothy Leaf, Ruchir P. Desai, Jorge L. Galazzo, Greg O. Buchanan, Stephen William Watt, Alexander Redvers Eberlin, Robert Arslanian
  • Method of producing a compound by fermentation
    Patent number: 7459294
    Abstract: During the production of a product compound by fermentation, the concentration of a precursor compound is maintained within a pre-selected concentration range by having an adsorbent resin in contact with the culture medium. The adsorbent resin reversibly adsorbs precursor compound and, as un-adsorbed precursor compound is converted to product compound, adsorbed precursor compound is released from the resin, thus maintaining the concentration of precursor compound within the pre-selected range.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: December 2, 2008
    Assignee: Kosan Biosciences Incorporated
    Inventors: Timothy A. Leaf, Ruchir P. Desai, Peter Licari, Elaine Jennifer Woo
  • 17-Allylamino-17-demethoxygeldanamycin polymorphs and formulations
    Publication number: 20070203110
    Abstract: Polymorphs and pharmaceutical formulations of 17-allylamino-17-demethoxygeldanamycin (17-AAG).
    Type: Application
    Filed: November 8, 2006
    Publication date: August 30, 2007
    Inventors: Peter Licari, Timothy Leaf, Ruchir Desai, Jorge Galazzo, Greg Buchanan, Stephen Watt, Alexander Eberlin, Robert Arslanian
  • Method of producing a compound by fermentation
    Publication number: 20050130283
    Abstract: During the production of a product compound by fermentation, the concentration of a precursor compound is maintained within a pre-selected concentration range by having an adsorbent resin in contact with the culture medium. The adsorbent resin reversibly adsorbs precursor compound and, as un-adsorbed precursor compound is converted to product compound, adsorbed precursor compound is released from the resin, thus maintaining the concentration of precursor compound within the pre-selected range.
    Type: Application
    Filed: August 6, 2004
    Publication date: June 16, 2005
    Applicant: Kosan Biosciences, Inc.
    Inventors: Timothy Leaf, Ruchir Desai, Peter Licari, Elaine Woo