Abstract: A training system includes a computer system, a display system and a motion capture device. During use the training system presents a computer simulation of a virtual subject capable of exhibiting nystagmus to a trainee. The movements of the trainee are captured using the computer system during the administration of an HGN test to the virtual subject. During the administration of the HGN test to the virtual subject, the training system simulates nystagmus in the virtual subject.

Abstract: A technique for improving application window displays in a multi-window graphical user interface in a touch-based computing device is discussed. By selecting an application window or corresponding thumbnail icon in a multi-window graphical user interface using a finger touch and dragging the application window or icon to an edge of the screen indicated by another finger, the edge of the selected application window may be automatically aligned with respect to that screen edge. Additionally, already open application windows may be automatically re-sized and re-positioned to accommodate the newly re-sized application window.

Abstract: The invention provides murine, chimeric, and humanized antibodies that specifically bind to CD48 and conjugates thereof.

Abstract: A system adaptably directs packet flows to packet processing elements based on OSI layer characteristics and, when necessary, inspection of data payloads. Characteristics of parsed data flows are identified. A comparison ensues. Upon recognition of a match, the entirety of the packet flow is directed to a linked packet processing element. When a match does not occur, the packet flow is directed to a second analysis tier whereby data payloads of the flow are examined. Characteristics from the data payload analysis are compared to entries in a database. Upon a match being recognized the matching packet flow is directed to the packet processing element. Features of packet flow having undergone data payload analysis are captured and used to update the database of prior associations so that any subsequent receipt of similar packet flows will be forwarded to the linked packet processing element without having to conduct a data payload analysis.

Abstract: The present invention relates to a drug delivery device for setting and dispensing of a dose of a medicament is presented comprising a housing to accommodate a cartridge filled with the medicament, an electrically operated drive mechanism to be operably engaged with the cartridge to expel a predefined dose of the medicament from the cartridge, and at least one dose element displaceably arranged relative to the housing to set and/or to dispense the dose of the medicament, wherein the dose element and the drive mechanism are mechanically decoupled from each other.

Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of malaria.

Abstract: Provided are novel anti-CD228 antibodies and antibody-drug conjugates and methods of using such anti-CD228 antibodies and antibody-drug conjugates to treat cancer.

Abstract: The present invention provides 6-phenyl-4,5-dihydropyridazin-3(2H)-one derivatives of formula (I): The present invention provides 6-phenyl-4,5-dihydropyridazin-3(2H)-one derivatives of formula (I):

Abstract: The invention provides murine, chimeric, and humanized antibodies that specifically bind to CD48 and conjugates thereof.

Abstract: Disclosed are compounds that can be used for treating tuberculosis.

Abstract: The present invention relates to a segmented, combination level and square that has a sliding and/or magnetic joint. In a preferred embodiment, this hand tool provides the user with many optional tools in one. The tool can be configured as a spirit level, framing square or a pocket square. In a preferred embodiment, this multi-segmented combination tool also provides the user with a convenient way not only to configure a level, in one inch increments, to any length from twelve inches to at least ninety six inches in length, but also to create more than one tool at a time such as a pocket square and a framing square. In other preferred embodiments, the user is provided with optional features that enable them to carry on-site a single tool that can perform all tasks to do general construction layout such as roof framing.

Abstract: The present invention features improved compounds, especially the compound having the structure (1). Compositions and methods of identifying patients having cancer using biomarkers (e.g., PDE3A, PDE3B, SLFN12 and/or CREB3L1) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention.

Abstract: A firmware-based technique for using one or more symmetric keys generated from one or more user credentials to decrypt user profile information and authenticate the user before allowing access to firmware-provided services is discussed. Exemplary credential types include user passwords, smart card data, fingerprint sensor data and retinal scan data. The credentials may be verified in a resource-constrained pre-operating system (OS) environment, upon control of the computing device being returned to the firmware by the OS, and/or may enable recovery scenarios executed by the firmware, such as in the case where a password is lost.

Abstract: The present invention features improved Compounds, especially (I) methods of identifying patients having Cancer using biomarkers (e.g., PDE3A, SLFN12 and/or CREB3L1) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention (e.g., Compounds 1-6 disclosed herein).

Abstract: A portable liquid-filtration device includes an inlet port, a filtering portion including a filtering medium and fluidly coupled to the inlet port, a filtered-liquid output port fluidly coupled to the filtering portion, a flush port fluidly coupled to the filtering portion, and a manually activated pump assembly fluidly coupled to the inlet port, filtering portion, output port and flush port. The pump assembly is configured, when activated, to create a negative fluid pressure at the inlet port and a positive fluid pressure at the output port and the flush port. As a consequence of activation of the pump assembly, the filtering portion receives unfiltered liquid from the inlet port, the output port receives from the filtering portion only liquid traversing the filtering medium in a first direction, and the flush port receives from the filtering portion liquid traversing the filtering medium in a second direction different from the first direction.

Abstract: A computer-implemented method for processing test financial transactions that includes accessing, via a remote-control server, transaction data corresponding to a test run. The transaction data is transmitted via the remote-control server and received at a mobile application API of an electronic device. The transaction data is passed to a payment application of the electronic device. A cryptogram corresponding to the transaction data is generated via the payment application and transmitted for submission to a payment network. A transaction response corresponding to the test run is received at the remote-control server.

Abstract: A computer-implemented method for processing test financial transactions that includes executing a mobile application API at an electronic device and receiving a command to initiate a transaction at the mobile application API, the command including transaction data. A payment application is executed at the electronic device to generate additional transaction data comprising a cryptogram based at least in part on the transaction data. The cryptogram and a corresponding post transaction command are transmitted. A web service API executed at a web service server receives the cryptogram and the corresponding post transaction command. A transaction request including at least some of the transaction data is generated at the web service API, according to interchange standards of a payment network, and transmitted to the payment network.

Abstract: Disclosed are compounds that can be used for treating tuberculosis.