Patents by Inventor Timothy Luker

Timothy Luker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds
    Patent number: 8158820
    Abstract: The invention relates to substituted phenoxyacetic acids (I) as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: April 17, 2012
    Assignee: AstraZeneca AB
    Inventors: Roger Bonnert, Stephen Brough, Andrew Davies, Timothy Luker, Thomas McInally, Ian Millichip, Garry Pairaudeau, Anil Patel, Rukhsana Rasul, Stephen Thom
  • Novel Compounds
    Publication number: 20110166117
    Abstract: The invention relates to substituted phenoxyacetic acids (I) as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.
    Type: Application
    Filed: December 30, 2010
    Publication date: July 7, 2011
    Inventors: Roger Bonnert, Stephen Brough, Andrew Davies, Timothy Luker, Thomas McInally, Ian Millichip, Garry Pairaudeau, Anil Patel, Rukhsana Rasul, Stephen Thom
  • Adamantane derivatives
    Publication number: 20090176853
    Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).
    Type: Application
    Filed: December 4, 2008
    Publication date: July 9, 2009
    Inventors: Lilian Alcaraz, Moya Caffrey, Mark Furber, Timothy Luker, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis
  • Novel Compounds
    Publication number: 20080255150
    Abstract: The invention relates to substituted aryl acids as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.
    Type: Application
    Filed: November 1, 2006
    Publication date: October 16, 2008
    Applicant: ASTRAZENECA AB
    Inventor: Timothy Luker
  • Adamantane derivatives
    Publication number: 20080139636
    Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).
    Type: Application
    Filed: June 20, 2007
    Publication date: June 12, 2008
    Inventors: Lilian Alcaraz, Moya Caffrey, Mark Furber, Timothy Luker, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis
  • Substituted Acids for the Treatment of Respiratory Diseases
    Publication number: 20080114002
    Abstract: The invention relates to substituted acids of formula (I), where T, W, X, Y, Z, R1 and R2 as defined in the claims, as useful pharmaceutical compounds for treating asthma and rhinitis, pharmaceutical compositions containing them, and a processes for their preparation.
    Type: Application
    Filed: July 6, 2005
    Publication date: May 15, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Roger Bonnert, Stephen Thom, Anil Patel, Timothy Luker
  • Modulators of Crth-2 Receptor Activity for the Treatment of Prostaglandin D2 Mediated Diseases
    Publication number: 20070249686
    Abstract: The invention relates to substituted acids as useful pharmaceutical compounds for treating respiratory disorders as asthma, pharmaceutical compositions containing them, and processes for their preparation.
    Type: Application
    Filed: October 3, 2005
    Publication date: October 25, 2007
    Applicant: ASTRAZENECA AB
    Inventors: Roger Bonnert, Timothy Luker, Garry Pairaudeau, Stephen Thom
  • Adamantane derivatives
    Publication number: 20070082957
    Abstract: The invention provides adamantane derivatives of formula (I), a process for the their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).
    Type: Application
    Filed: September 29, 2006
    Publication date: April 12, 2007
    Inventors: Lilian Alcaraz, Moya Caffrey, Mark Furber, Timothy Luker, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis
  • Novel n-substituted 2-aminopyridine derivatives
    Publication number: 20060270714
    Abstract: There are provided novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R17, L1, L2, L3 and Q are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease and pain.
    Type: Application
    Filed: March 30, 2004
    Publication date: November 30, 2006
    Inventors: David Cheshire, Stephen Connolly, Timothy Luker, Jeffrey Stonehouse
  • Substituted indole derivatives for pharmaceutical compositions for treating respiratory diseases
    Publication number: 20060264444
    Abstract: The present invention relates to substituted indoles of formula (I) useful as pharmaceutical compounds for treating respiratory disorders.
    Type: Application
    Filed: August 16, 2004
    Publication date: November 23, 2006
    Inventors: Roger Bonnert, Anthony Cook, Timothy Luker, Rukhsana Mohammed, Stephen Thom
  • Novel compounds
    Publication number: 20060264435
    Abstract: The invention relates to substituted phenoxyacetic acids (I) as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.
    Type: Application
    Filed: April 6, 2004
    Publication date: November 23, 2006
    Inventors: Roger Bonnert, Stephen Brough, Andrew Davies, Timothy Luker, Thomas McInally, Ian Millichip, Garry Pairaudeau, Anil Patel, Rukshana Rasul, Stephen Thom
  • Novel 6-substituted 2-aminopyridine derivatives
    Publication number: 20060194847
    Abstract: There are provided novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, L1, L2, L3 and Q are are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease and pain.
    Type: Application
    Filed: March 30, 2004
    Publication date: August 31, 2006
    Inventors: David Cheshire, Stephen Connolly, Timothy Luker
  • Adamantane derivatives
    Patent number: 6881754
    Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).
    Type: Grant
    Filed: December 12, 2000
    Date of Patent: April 19, 2005
    Assignee: AstraZeneca AB
    Inventors: Lilian Alcaraz, Moya Caffrey, Mark Furber, Timothy Luker, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis
  • Novel arylheteroalkylamine derivatives
    Publication number: 20040242871
    Abstract: There are provided novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, T, U, X, Y, V and W are as defined in the specification, and pharmaceutically acceptable salts thereof, and enantiomers and racemates thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease and pain.
    Type: Application
    Filed: January 8, 2004
    Publication date: December 2, 2004
    Inventors: Tim Birkinshaw, Stephen Connolly, Timothy Luker, Antonio Mete, Ian Millichip
  • Heteroarylheteroalkylamine derivatives and their use as inhibitors of nitric oxide synthase
    Publication number: 20040176422
    Abstract: There are provided novel compounds of formula (I), wherein R1, R2, R3, Q, T, U, X, Y, V and W are as defined in the specification, and pharmaceutically acceptable salts thereof, and enantiomers and racemates thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease and pain.
    Type: Application
    Filed: January 8, 2004
    Publication date: September 9, 2004
    Inventors: Timothy Birkinshaw, David Cheshire, Stephen Connolly, Timothy Luker, Antonio Mete
  • Adamantane derivatives
    Patent number: 6720452
    Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: April 13, 2004
    Assignee: AstraZeneca AB
    Inventors: Lilian Alcaraz, Mark Furber, Timothy Luker, Michael Mortimore, Philip Thorne
  • Adamantane derivatives
    Publication number: 20030013704
    Abstract: 1
    Type: Application
    Filed: June 12, 2002
    Publication date: January 16, 2003
    Inventors: Lilian Alcaraz, Moya Caffrey, Mark Furber, Timothy Luker, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis
  • Adamantane derivatives
    Publication number: 20020193414
    Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy.
    Type: Application
    Filed: June 10, 2002
    Publication date: December 19, 2002
    Inventors: Lillian Alcaraz, Mark Furber, Timothy Luker, Michael Mortimore, Philip Thorne
  • Pressurized container
    Patent number: D338395
    Type: Grant
    Filed: June 27, 1990
    Date of Patent: August 17, 1993
    Inventor: Timothy Luker