Abstract: This disclosure provides peptides which can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer; treating infectious diseases; enhancing a response to vaccination; treating sepsis; and promoting hair re-pigmentation or lightening of pigmented skin lesions.

Abstract: A spherical plain bearing is provided having improved wear resistance under heavy axial and radial loads of a rotating shaft. The bearing includes a pillow block having a concave inner surface, a split cylindrical protective sleeve for mating with and detachably clamping around the shaft, the outer surface of the sleeve having a peripheral recess. The bearing includes a split cylindrical liner having an inner wear resistant surface for sliding contact within the recess of the protective sleeve, and multiple thrust plate rings, and a split cylindrical cartridge for holding the liner in the recess of the protective sleeve. The bearing includes a plurality of high wear-resistant elements for providing high wear resistance and low friction resistance when placed into the wear surfaces of the bearing.