Patents by Inventor Timothy McCauley
Timothy McCauley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11958864Abstract: The present invention relates to Tetracyclic Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts or prodrug thereof, wherein R1 is as defined herein. The present invention also relates to compositions comprising at least one Tetracyclic Heterocycle Compound, and methods of using the Tetracyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.Type: GrantFiled: February 14, 2022Date of Patent: April 16, 2024Assignee: Merck Sharp & Dohme LLCInventors: Timothy John Hartingh, John A. McCauley, Tao Yu, Yonglian Zhang
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Patent number: 11826104Abstract: A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. The gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.Type: GrantFiled: May 27, 2021Date of Patent: November 28, 2023Assignee: Glaukos CorporationInventors: Charles Raymond Kalina, Jr., Thomas W. Burns, Chris Calcaterra, Edward Collins, Timothy McCauley, David S. Haffner, Steven M. Henderson
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Publication number: 20220015628Abstract: A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. The gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.Type: ApplicationFiled: May 27, 2021Publication date: January 20, 2022Inventors: Charles Raymond Kalina, JR., Thomas W. Burns, Chris Calcaterra, Edward Collins, Timothy McCauley, David S. Haffner, Steven M. Henderson
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Patent number: 11019996Abstract: A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. The gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.Type: GrantFiled: December 6, 2019Date of Patent: June 1, 2021Assignee: GLAUKOS CORPORATIONInventors: Charles Raymond Kalina, Jr., Thomas W. Burns, Chris Calcaterra, Edward Collins, Timothy McCauley, David S. Haffner, Steven M. Henderson
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Patent number: 11019997Abstract: A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. The gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.Type: GrantFiled: December 9, 2019Date of Patent: June 1, 2021Inventors: Charles Raymond Kalina, Jr., Thomas W. Burns, Chris Calcaterra, Edward Collins, Timothy McCauley, David S. Haffner, Steven M. Henderson
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Publication number: 20200214560Abstract: A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. The gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.Type: ApplicationFiled: December 6, 2019Publication date: July 9, 2020Inventors: Charles Raymond Kalina, JR., Thomas W. Burns, Chris Calcaterra, Edward Collins, Timothy McCauley, David S. Haffner, Steven M. Henderson
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Publication number: 20200214561Abstract: A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. The gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.Type: ApplicationFiled: December 9, 2019Publication date: July 9, 2020Inventors: Charles Raymond Kalina, JR., Thomas W. Burns, Chris Calcaterra, Edward Collins, Timothy McCauley, David S. Haffner, Steven M. Henderson
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Patent number: 10499809Abstract: A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. The gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.Type: GrantFiled: March 18, 2016Date of Patent: December 10, 2019Assignee: Glaukos CorporationInventors: Charles Raymond Kalina, Jr., Thomas W. Burns, Chris Calcaterra, Edward Collins, Timothy McCauley, David S. Haffner, Steven M. Henderson
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Publication number: 20180070817Abstract: A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. The gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.Type: ApplicationFiled: March 18, 2016Publication date: March 15, 2018Inventors: Charles Raymond Kalina, JR., Thomas W. Burns, Chris Calcaterra, Edward Collins, Timothy McCauley, David S. Haffner, Steven M. Henderson
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Publication number: 20050106655Abstract: An assay is disclosed for measuring activity of enzymes, such as kinases, phosphatases, and proteases. Measurements of enzymatic activity are accomplished in a homogenous assay format utilizing a fluorescence quenching technique employing paramagnetic metal ions.Type: ApplicationFiled: June 14, 2004Publication date: May 19, 2005Inventors: M. Savage, Timothy McCauley, Sherri Millis