Abstract: In some embodiments, an implant includes a substrate and a radiopaque portion. The radiopaque portion is coupled to the substrate. The radiopaque portion has a first portion extending along a first axis and a second portion extending along a second axis different than the first axis. In some embodiments, the substrate has a perimeter that defines a shape having a first size. The radiopaque portion forms a shape having a second size. The shaped formed by the radiopaque portion is substantially the same as the shape defined by the perimeter of the substrate. The first size is greater than the second size.

Abstract: According to one aspect of the invention, composite implants for soft tissue repair a provided which comprise (a) a substantially two-dimensional piece of biologic matrix material and (b) one or more non-absorbable synthetic polymeric filaments.

Abstract: A method of reducing adhesion at a site of trauma includes forming a film from an alginate solution, contacting the film with a cross-linking solution to form a cross-linked mechanically stable sheet, and placing at least a portion of the sheet at the site of trauma. An anti-adhesion barrier includes a sheet of ionically cross-linked alginate having a thickness in a range of 0.25 mm to 10 mm. The sheet has a tear strength sufficient for suturing and repositioning. A drug delivery device includes a cross-linked alginate container that can be filled with a drug.

Abstract: A method of reducing adhesion at a site of trauma includes forming a film from an alginate solution, contacting the film with a cross-linking solution to form a cross-linked mechanically stable sheet, and placing at least a portion of the sheet at the site of trauma. An anti-adhesion barrier includes a sheet of ionically cross-linked alginate having a thickness in a range of 0.25 mm to 10 mm. The sheet has a tear strength sufficient for suturing and repositioning. A drug delivery device includes a cross-linked alginate container that can be filled with a drug.