Abstract: The present invention generally relates to methods and compositions to determine viability of an organ for transplantation and other medical purposes. One aspect of the invention relates to a method for assessing the viability of an organ by measuring the energy parameters to determine the energy level of the organ by determining the stored cellular energy (e.g., ATP levels), and/or energy consumption over a particular time period of viability. The energy parameters can be compared to reference energy parameters as a highly accurate and reliable prediction of viable cell yield, and organ viability. Another aspect of the invention relates methods to preserve or extend the time period of viability of an organ any combination of (i) preservation perfusion of the organ to prevent ischemic damage, (ii) chemical metabolic suppression of the organ e.g., using metabolic suppressants, (iii) metabolic suppression by physical or environmental conditions, e.g., sub-zero non-freezing storage.

Abstract: A method and apparatus for tracking disease progression as revealed by multiple lesions perform a global optimization to identify corresponding lesions by overlap, for example, after outlines of the lesions have been morphologically dilated. A clustering algorithm addresses the problem of lesions separating into parts or joining together to provide a clear picture of disease progression.

Abstract: A method and apparatus for tracking disease progression as revealed by multiple lesions perform a global optimization to identify corresponding lesions by overlap, for example, after outlines of the lesions have been morphologically dilated. A clustering algorithm addresses the problem of lesions separating into parts or joining together to provide a clear picture of disease progression.

Abstract: A system for monitoring organ health during treatment for cancer and the like makes use of physiological imaging of the kind used for treatment monitoring and organ-specific processing to provide a comprehensive assessment of treatment side-effects.

Abstract: A system for monitoring organ health during treatment for cancer and the like makes use of physiological imaging of the kind used for treatment monitoring and organ-specific processing to provide a comprehensive assessment of treatment side-effects.

Abstract: The present disclosure provides methods, systems, and non-transitory computer-readable media for assessment of disease treatment or progression on a lesion-by-lesion level. The systems and methods are based on measurements of a variety of features including total number of lesions, total number and proportion of lesions regressing or progressing, changes in dimensions of a lesion over time, and uptake values of a molecular imaging agent.

Abstract: A method and apparatus for tracking disease progression as revealed by multiple lesions perform a global optimization to identify corresponding lesions by overlap, for example, after outlines of the lesions have been morphologically dilated. A clustering algorithm addresses the problem of lesions separating into parts or joining together to provide a clear picture of disease progression.

Abstract: A system for monitoring organ health during treatment for cancer and the like makes use of physiological imaging of the kind used for treatment monitoring and organ-specific processing to provide a comprehensive assessment of treatment side-effects.

Abstract: A standardized skeleton template is used to normalize medical image data of the skeleton to eliminate variations in the medical image data related to physiological variations in a normal patient thereby better accentuating disease conditions.

Abstract: A standardized skeleton template is used to normalize medical image data of the skeleton to eliminate variations in the medical image data related to physiological variations in a normal patient thereby better accentuating disease conditions.