Patents by Inventor Timothy Powers
Timothy Powers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11975046Abstract: The present invention relates to methods for the treatment of fibrosis. The invention discloses new research which demonstrates that interferon-lambda has directly acting anti-fibrotic effects both in vitro and in vivo and may be used to provide effective new therapies for the treatment of multiple types of fibrosis.Type: GrantFiled: June 29, 2023Date of Patent: May 7, 2024Assignees: UCB BIOPHARMA SRL, FIVE PRIME THERAPEUTICS, INC.Inventors: Timothy Scott Johnson, Breda Twomey, Janine Powers, Danielle E. Kellar
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Publication number: 20240084678Abstract: A housing for an electrical component of a gun system is disclosed. The housing includes a housing body, an uphole bulkhead, and a downhole bulkhead. The housing body defines a cavity. The uphole bulkhead is disposed at least partially within the cavity. The downhole bulkhead is disposed at least partially within the cavity and opposite to the uphole bulkhead. The downhole bulkhead includes an electrical contact extending between a first end and a second end of the downhole bulkhead. The cavity, the uphole bulkhead, and the second end of the downhole bulkhead define a sealed volume configured to receive and isolate the electrical component. The electrical contact is configured to be electrically connected to the electrical component.Type: ApplicationFiled: September 8, 2022Publication date: March 14, 2024Applicant: GEODynamics, Inc.Inventors: Michael Wroblicky, Carson Brooks, Seth Powers, Timothy Wayne Sampson
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Patent number: 11235323Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: GrantFiled: August 30, 2019Date of Patent: February 1, 2022Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
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Patent number: 11132371Abstract: A computer implemented method, computerised system and computer readable recording medium are disclosed.Type: GrantFiled: December 14, 2018Date of Patent: September 28, 2021Assignee: INQUISITIVE PTY LIMITEDInventors: Timothy Power, Luke Tomes, Mitchell Lane
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Publication number: 20210216560Abstract: A computer implemented method, computerised system and computer readable recording medium are disclosed.Type: ApplicationFiled: December 14, 2018Publication date: July 15, 2021Inventors: Timothy Power, Luke Tomes, Mitchell Lane
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Publication number: 20200197934Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: ApplicationFiled: August 30, 2019Publication date: June 25, 2020Inventors: Joseph AMSHEY, Daniel BEZDEK, Espir KAHATT, Alexander KHORLIN, Lance PARSONS, Todd PETERSON, Timothy POWERS, Michael THACKER, Timothy UPDYKE, Kornelija ZGONC
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Patent number: 10434509Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: GrantFiled: September 28, 2017Date of Patent: October 8, 2019Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
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Publication number: 20180258100Abstract: In various embodiments novel rapamycin analogs are provides that show improved mTORC1 specificity.Type: ApplicationFiled: August 26, 2016Publication date: September 13, 2018Inventors: Matthew Alan GREGORY, Steven MOSS, Michael VELARDE, Timothy POWERS, Stelios TZANNIS
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Publication number: 20180111121Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: ApplicationFiled: September 28, 2017Publication date: April 26, 2018Inventors: Joseph AMSHEY, Daniel BEZDEK, Espir KAHATT, Alexander KHORLIN, Lance PARSONS, Todd PETERSON, Timothy POWERS, Michael THACKER, Timothy UPDYKE, Kornelija ZGONC
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Patent number: 9808799Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: GrantFiled: August 19, 2014Date of Patent: November 7, 2017Assignee: Life Technologies CorporationInventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
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Patent number: 9296698Abstract: The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I wherein ring A, B1, B2, B3, L, R1, R4, R5 and m of Formula I are defined herein. The invention also includes use of these compounds in pharmaceutical compositions for treatment, prophylactic or therapeutic, of disorders and conditions related to the activity of beta-secretase protein. Such disorders include, for example, Alzheimer's Disease (AD), cognitive deficits, cognitive impairment, schizophrenia and other central nervous system conditions related to and/or caused by the formation and/or deposition of plaque on the brain. The invention also comprises further embodiments of Formula I, intermediates and processes useful for the preparation of compounds of Formula I.Type: GrantFiled: November 19, 2010Date of Patent: March 29, 2016Assignee: Amgen Inc.Inventors: Yuan Cheng, Timothy Powers, Kate Ashton, James Brown, Scott Harried, Stephen A. Hitchcock, Ted Judd, Patricia Lopez, Thomas Nixey, Nick A. Paras, Steve F. Poon, David J. St. Jean, Jr., Qiufen Xue, Wenge Zhong
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Patent number: 9012446Abstract: The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I wherein A1, A2, A3, A4, A5, A6, R2, R7, X, Y and Z of Formula I are defined herein. The invention also includes use of these compounds in pharmaceutical compositions for treatment, prophylactic or therapeutic, of disorders and conditions related to the activity of beta-secretase protein. Such disorders include, for example, Alzheimer's Disease, cognitive deficits, cognitive impairment, schizophrenia and other central nervous system conditions related to and/or caused by the formation and/or deposition of plaque on the brain. The invention also comprises further embodiments of Formula I, intermediates and processes useful for the preparation of compounds of Formula I.Type: GrantFiled: June 27, 2013Date of Patent: April 21, 2015Assignee: Amgen Inc.Inventors: Jian Chen, Wenge Zhong, Patricia Lopez, Ryan White, Matthew Weiss, Ted Judd, Timothy Powers, Yuan Cheng, Thomas Dineen, Jonathan D. Low, Isaac E. Marx, Ana Elena Minatti
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Publication number: 20150044758Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: ApplicationFiled: August 19, 2014Publication date: February 12, 2015Inventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
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Publication number: 20150023468Abstract: A portable x-ray system includes a light weight x-ray head including an x-ray tube and a high voltage (HV) tank, wherein the HV tank comprises a compact voltage multiplier configured to receive a low voltage signal and generate a high voltage signal based on the received low voltage signal. Also, the portable x-ray system includes a carrying case comprising low voltage power electronics coupled to the light weight x-ray head through a low voltage cable, and configured to send the low voltage signal to the light weight x-ray head. In addition, the low voltage power electronics is distributed in a predefined space in the carrying case in such a way that a weight of the light weight x-ray head is counter weighed by a weight of the low voltage power electronics to stabilize the portable x-ray system when the light weight x-ray head is rotated in one or more directions.Type: ApplicationFiled: July 17, 2013Publication date: January 22, 2015Inventors: Yun Zou, Scott Stephen Zelakiewicz, Fengfeng Tao, Xi Zhang, Timothy Powers, Thomas Edmund Sjoberg, Marc Weasler, Denis Perrillat-Amede
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Patent number: 8923484Abstract: A motion correction system and method for motion correction for an x-ray tube is presented. One embodiment of the motion correction system includes a sensing unit coupled to an x-ray tube to determine a distance with which an impingement location of an electron beam generated by the x-ray tube deviates from a determined location due to motion of the x-ray tube. The motion correction system further includes a control unit coupled to the sensing unit to generate a control signal corresponding to the distance with which the impingement location of the electron beam deviates. Also, the motion correction system includes a deflection unit coupled to the control unit to steer the electron beam to the determined location based on the generated control signal.Type: GrantFiled: August 31, 2012Date of Patent: December 30, 2014Assignee: General Electric CompanyInventors: Yun Zou, Scott Stephen Zelakiewicz, Floribertus P. M. Heukensfeldt Jansen, Jeffrey Wayne Eberhard, Fengfeng Tao, Timothy Powers, Thomas Edmund Sjoberg
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Patent number: 8845984Abstract: The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing.Type: GrantFiled: September 13, 2012Date of Patent: September 30, 2014Assignee: Life Technologies CorporationInventors: Joseph Amshey, Daniel Bezdek, Espir Kahatt, Alexander Khorlin, Lance Parsons, Todd Peterson, Timothy Powers, Michael Thacker, Timothy Updyke, Kornelija Zgonc
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Patent number: 8822485Abstract: The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I, wherein ring A, B1, B2, B3, L, R1, R4, ring Z, m and p of Formula I are defined herein. The invention also includes use of these compounds in pharmaceutical compositions for treatment, prophylactic or therapeutic, of disorders and conditions related to the activity of beta-secretase protein. Such disorders include, for example, Alzheimer's Disease (AD), cognitive deficits, cognitive impairment, schizophrenia and other central nervous system conditions related to and/or caused by the formation and/or deposition of plaque on the brain. The invention also comprises further embodiments of Formula I, intermediates and processes useful for the preparation of compounds of Formula I.Type: GrantFiled: November 19, 2010Date of Patent: September 2, 2014Assignee: Amgen Inc.Inventors: Nick A. Paras, Yuan Cheng, Timothy Powers, James Brown, Stephen A. Hitchcock, Ted Judd, Patricia Lopez, Qiufen Xue, Bryant Yang
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Patent number: 8807044Abstract: An apparatus and system whereby a first member can move along a cable track and then on a glide track to then move in another direction and back on a glide track. The first member has a secondary retention system disposed therein.Type: GrantFiled: September 15, 2011Date of Patent: August 19, 2014Inventors: James Liggett, Troy Lee Garland, Timothy Powers
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Patent number: 8735384Abstract: The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula (I); wherein ring A, B1, B2, B3, L, R1, R2, ring Z, m and n of Formula I are defined herein. The invention also includes use of these compounds in pharmaceutical compositions for treatment, prophylactic or therapeutic, of disorders and conditions related to the activity of beta-secretase protein. Such disorders include, for example, Alzheimer's Disease (AD), cognitive deficits, cognitive impairment, schizophrenia and other central nervous system conditions related to and/or caused by the formation and/or deposition of plaque on the brain. The invention also comprises further embodiments of Formula (I), intermediates and processes useful for the preparation of compounds of Formula (I).Type: GrantFiled: January 14, 2011Date of Patent: May 27, 2014Assignee: Amgen Inc.Inventors: Nick A. Paras, James Brown, Yuan Cheng, Stephen A. Hitchcock, Ted Judd, Patricia Lopez, Ana Elena Minatti, Thomas Nixey, Timothy Powers, Christopher M. Tegley, Qiufen Xue, Bryant Yang, Wenge Zhong
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Publication number: 20140064456Abstract: A motion correction system and method for motion correction for an x-ray tube is presented. One embodiment of the motion correction system includes a sensing unit coupled to an x-ray tube to determine a distance with which an impingement location of an electron beam generated by the x-ray tube deviates from a determined location due to motion of the x-ray tube. The motion correction system further includes a control unit coupled to the sensing unit to generate a control signal corresponding to the distance with which the impingement location of the electron beam deviates. Also, the motion correction system includes a deflection unit coupled to the control unit to steer the electron beam to the determined location based on the generated control signal.Type: ApplicationFiled: August 31, 2012Publication date: March 6, 2014Applicant: GENERAL ELECTRIC COMPANYInventors: Yun Zou, Scott Stephen Zelakiewicz, Floribertus P. M. Heukensfeldt Jansen, Jeffrey Wayne Eberhard, Fengfeng Tao, Timothy Powers, Thomas Edmund Sjoberg