Abstract: A medical image analysis system is for first and second anatomical image data of a same body area and subject to deformation. The medical image analysis system may include a processor cooperating with a memory to generate a deformation vector array between the first and second anatomical image data. The processor may also display, on a display, first and second anatomical images respectively based upon the first and second anatomical image data. A first cursor may be displayed on the first anatomical image, and a second cursor may be displayed on the second anatomical image based upon a mapping of the first cursor using the deformation vector array.

Abstract: A medical image analysis system is for first and second anatomical image data of a same body area and subject to deformation. The first and second anatomical image data includes respective first and second sets of voxels. The medical image analysis system includes a processor cooperating with a memory to generate a respective reach array for each voxel of the second anatomical image data, with each reach array being a subset of contiguous voxels. The processor also generates a cost array for each reach array, with each cost array based upon probabilities of voxels of the reach array matching voxels of the first anatomical image data. The processor may also solve each cost array using belief propagation to thereby generate a deformation vector array between the first and second anatomical image data.

Abstract: A medical image analysis system is for first and second anatomical image data of a same body area and subject to deformation, with the first and second anatomical image data including respective first and second sets of voxels. The medical image analysis system may include a processor cooperating with a memory and configured to generate a plurality of cost arrays, with each cost array based upon probabilities of a subset of voxels of the second anatomical image data matching voxels of the first anatomical image data. The processor may also solve each cost array using three-dimensional, N-way belief propagation to thereby generate a deformation vector array between the first and second anatomical image data, where N is an integer greater than or equal to six.

Abstract: A method for converting between source coordinates in a source coordinate system and target coordinates in a target coordinate system includes the step of defining a coordinate system conversion tree extending from a root coordinate system and branching to a plurality of other coordinate-systems including the source and target coordinate systems so that the source and target coordinate systems are connected to a common coordinate system other than the root coordinate system. Coordinate conversions are performed between the source and target coordinates along branches extending from the source coordinate system to the common coordinate system and to the target coordinate system without returning to the root coordinate system. Contextual data is associated with the coordinates to permit conversion to an adjacent coordinate system.