Patents by Inventor Timothy R. Machold

Timothy R. Machold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10398437
    Abstract: Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: September 3, 2019
    Assignee: MVRx, Inc.
    Inventors: Timothy R. Machold, Robert T. Chang, David A. Rahdert, David Scott, David R. Tholfsen
  • Patent number: 10369044
    Abstract: A method for treating acute coronary syndromes (i.e., unstable angina or non-Q-wave MI) or transient ischemic attacks in a human or animal patient by placing a heat exchange apparatus in the patient=s vasculature and using that heat exchange apparatus to cool the patient to a temperature (e.g. 30-36 degrees C.) at which platelet inhibition (i.e., inhibition of platelet activation and/or aggregation and/or adhesion) occurs. Anti-shivering drugs or anesthesia may be administered to patients whose body temperature is cooled below that patient=s shivering threshold (typically approximately 35.5 degrees C.). If it is determined that platelet inhibition is no longer desirable, such as when the patient is about to undergo a surgical or interventional procedure wherein bleeding could be problematic, the hypothermia-induced platelet inhibition may be rapidly reversed by using the intravascular heat exchange apparatus to re-warm the patient=s body to normothermia or near normothermia.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: August 6, 2019
    Assignee: ZOLL Circulation, Inc.
    Inventors: Michael W. Dae, Timothy R. Machold, Wade A. Keller
  • Publication number: 20190183645
    Abstract: Anchors for securing an implant within a body organ and/or reshaping a body organ are provided herein. Anchors are configured for deployment in a body lumen or vasculature of the patient that are curved or conformable to accommodate anatomy of the patient. Such anchors can include deformable or collapsible structures upon tensioning of a bridging element in a lateral direction, or segmented tubes that can be adjusted by tightening of one or more tethers extending therethrough. Such anchors can be used as a posterior anchor in a blood vessel in implant systems having a tensioned bridging element extending between the posterior anchor and an anterior anchor deployed at another location within or along the body organ. Methods of deploying such anchors, and use of multiple anchors or multiple bridging elements to a single anchor are also provided.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 20, 2019
    Applicant: MVRx, Inc.
    Inventors: Timothy R. Machold, David A. Rahdert, Robert T. Chang, Ganesh Manoharan
  • Publication number: 20190175343
    Abstract: Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the right atrium, which allow tricuspid valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant. The implants or systems of implants and methods may utilize a bridge stop to secure the implant.
    Type: Application
    Filed: December 5, 2018
    Publication date: June 13, 2019
    Inventors: Robert T. Chang, Timothy R. Machold, David A. Rahdert, Jason Rogers
  • Patent number: 10278818
    Abstract: Anchors for securing an implant within a body organ and/or reshaping a body organ are provided herein. Anchors are configured for deployment in a body lumen or vasculature of the patient that are curved or conformable to accommodate anatomy of the patient. Such anchors can include deformable or collapsible structures upon tensioning of a bridging element in a lateral direction, or segmented tubes that can be adjusted by tightening of one or more tethers extending therethrough. Such anchors can be used as a posterior anchor in a blood vessel in implant systems having a tensioned bridging element extending between the posterior anchor and an anterior anchor deployed at another location within or along the body organ. Methods of deploying such anchors, and use of multiple anchors or multiple bridging elements to a single anchor are also provided.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: May 7, 2019
    Assignee: MVRx, Inc.
    Inventors: Timothy R. Machold, David A. Rahdert, Robert T. Chang, Ganesh Manoharan
  • Publication number: 20190083300
    Abstract: Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette of any one of several disclosed variations is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within one of various described re-usable control units. The control units include a heater/cooler device, a user input device, and a processor connected to receive input from various sensors around the body and the system. The heater/cooler device may be thermoelectric to enable both heating and 15? cooling based on polarity. A temperature control scheme for ramping the body temperature up or down without overshoot is provided.
    Type: Application
    Filed: September 7, 2018
    Publication date: March 21, 2019
    Applicant: Zoll Circulation, Inc.
    Inventors: Timothy R. Machold, Wade A. Keller, Alex T. Roth, Nicole Denise Bloom
  • Patent number: 10219902
    Abstract: Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial adjustability and retrievability years after implant. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize an adjustable bridge stop to secure the implant, and the methods of implantation employ various tools.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: March 5, 2019
    Assignee: MVRx, Inc.
    Inventors: Timothy R. Machold, David J. Scott, David A. Rahdert, David R. Tholfsen, Robert T. Chang, John A. Macoviak
  • Patent number: 10219905
    Abstract: Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: March 5, 2019
    Assignee: MVRx, Inc.
    Inventors: Robert T. Chang, John A. Macoviak, David A. Rahdert, Timothy R. Machold
  • Patent number: 10201423
    Abstract: Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the right atrium, which allow tricuspid valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant. The implants or systems of implants and methods may utilize a bridge stop to secure the implant.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: February 12, 2019
    Assignee: MVRx, Inc.
    Inventors: Robert T. Chang, Timothy R. Machold, David A. Rahdert, Jason Rogers
  • Publication number: 20190038410
    Abstract: Delivery systems, methods and associated devices to facilitate delivery and deployment of a heart implant. Such delivery systems and methods of delivery include use of a pair of magnetic catheters, including an anchor delivery catheter carrying an anchor, which can be stacked with or can be axially offset from the magnetic head. Such systems further include use of a puncturing guidewire advanceable through the magnetic head of the anchor delivery catheter to establish access to a chamber of a heart and which is attached to a bridging element such that continued advancement of the guidewire draws a bridging element attached to the first anchor across the chamber of the heart while the bridging element remains covered by the magnetically coupled catheters. Methods and devices herein also allow for cutting and removal of a bridge element of a deployed heart implant.
    Type: Application
    Filed: August 6, 2018
    Publication date: February 7, 2019
    Inventors: Timothy R. Machold, David R. Tholfsen
  • Patent number: 10172621
    Abstract: Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: January 8, 2019
    Assignee: MVRx, Inc.
    Inventors: Timothy R. Machold, Robert T. Chang, David A. Rahdert, David Scott, David R. Tholfsen
  • Patent number: 10085880
    Abstract: Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette of any one of several disclosed variations is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within one of various described re-usable control units. The control units include a heater/cooler device, a user input device, and a processor connected to receive input from various sensors around the body and the system. The heater/cooler device may be thermoelectric to enable both heating and 15? cooling based on polarity. A temperature control scheme for ramping the body temperature up or down without overshoot is provided.
    Type: Grant
    Filed: June 20, 2011
    Date of Patent: October 2, 2018
    Assignee: Zell Circulation, Inc.
    Inventors: Timothy R. Machold, Wade A. Keller, Alex T. Roth, Nicole Denise Bloom
  • Publication number: 20180055687
    Abstract: Catheter devices and methods for intravascular heating and/or cooling of human or veterinary patients. The catheter devices generally comprise catheters having inflow and outflow lumens and at least one curvilinear balloon connected to the inflow and outflow lumens such that heat exchange fluid may be circulated through the balloon(s). The catheter is inserted into the vasculature and heated or cooled fluid is circulated through the balloon(s) to heat or cool blood flowing in heat-exchange proximity to the balloon(s), thereby effecting heating or cooling of all or a portion of the patient's body.
    Type: Application
    Filed: August 22, 2017
    Publication date: March 1, 2018
    Inventors: Wade A. Keller, Timothy R. Machold
  • Patent number: 9861475
    Abstract: Devices, systems, and methods employ an implant that is sized and configured to attach to the annulus of a dysfunctional heart valve annulus. In use, the implant extends across the major axis of the annulus above and/or along the valve annulus. The implant reshapes the major axis dimension and/or other surrounding anatomic structures. The implant restores to the heart valve annulus and leaflets a more functional anatomic shape and tension. The more functional anatomic shape and tension are conducive to coaptation of the leaflets during systole, which, in turn, reduces regurgitation. The implant improves function to the valve, without surgically cinching, resecting, and/or fixing in position large portions of a dilated annulus, or without the surgical fixation of ring-like structures.
    Type: Grant
    Filed: August 12, 2009
    Date of Patent: January 9, 2018
    Assignee: MVRX INC.
    Inventors: Timothy R. Machold, David A. Rahdert, John A. Macoviak, Robert T. Chang, Rick A. Soss
  • Publication number: 20170266359
    Abstract: Devices, systems and methods for treating disorders characterized by low cardiac output. The devices, systems and methods use intra-aortic balloon counterpulsation in combination with hypothermia of all or a portion of a human or veterinary patient's body to improve coronary perfusion and cardiac output. To effect the hypothermia, a heat exchange catheter may be positioned in the a patient's vasculature separately from the intra-aortic balloon counterpulsation catheter. Alternatively, a combination Intra-aortic balloon counterpulsation/heat exchange catheter may be utilized. Such combination catheter comprises a) a catheter sized for insertion into the aorta, b) a counterpulsation balloon and c) a heat exchanger. A drive/control system receives temperature and electrocardiograph signals and drives the inflation/deflation of the counterpulsation balloon as well as the heating/cooling of the heat exchanger.
    Type: Application
    Filed: January 3, 2017
    Publication date: September 21, 2017
    Inventors: Michael W. Dae, Timothy R. Machold
  • Publication number: 20170216031
    Abstract: Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial adjustability and retrievability years after implant. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilise an adjustable bridge stop to secure the implant, and the methods of implantation employ various tools.
    Type: Application
    Filed: February 13, 2017
    Publication date: August 3, 2017
    Applicant: MVRX, INC.
    Inventors: Timothy R. Machold, David J. Scott, David A. Rahdert, David R. Tholfsen, Robert T. Chang, John A. Macoviak
  • Patent number: 9713483
    Abstract: The inventions described in this patent application include i) a torqueable introducer sheath which is useable in conjunction with a transvascular passageway forming catheter to effect precise rotational control of the catheter; ii) an anchorable guide catheter which is useable in conjunction with an intravascular imaging catheter and a transvascular passageway-forming catheter to effect precise positioning and aiming of the passageway-forming catheter; iii) a passageway forming catheter having a torqueable proximal portion to facilitate precise rotational positioning of the distal portion of the catheter; iv) a deflectable-tipped passageway forming catheter, v) various markers and other apparatus useable in conjunction with any of the passageway-forming catheters to facilitate precise positioning and aiming of the catheter, and vi) an apparatus which may be formed within a catheter to prevent a member, apparatus of flow of material from being inadvertently advanced through a lumen of the catheter.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: July 25, 2017
    Assignee: Medtronic Vascular, Inc.
    Inventors: Joshua Makower, J. Christopher Flaherty, Timothy R. Machold, Jason B. Whitt, Philip Christopher Evard, Patrick Edward Macaulay, John Thomas Garibotto, Margaret W Tumas, Alan Robert Selfridge
  • Publication number: 20170165068
    Abstract: Anchors for securing an implant within a body organ and/or reshaping a body organ are provided herein. Anchors are configured for deployment in a body lumen or vasculature of the patient that are curved or conformable to accommodate anatomy of the patient. Such anchors can include deformable or collapsible structures upon tensioning of a bridging element in a lateral direction, or segmented tubes that can be adjusted by tightening of one or more tethers extending therethrough. Such anchors can be used as a posterior anchor in a blood vessel in implant systems having a tensioned bridging element extending between the posterior anchor and an anterior anchor deployed at another location within or along the body organ. Methods of deploying such anchors, and use of multiple anchors or multiple bridging elements to a single anchor are also provided.
    Type: Application
    Filed: December 12, 2016
    Publication date: June 15, 2017
    Applicant: MVRx, Inc.
    Inventors: Timothy R. Machold, David A. Rahdert, Robert T. Chang, Ganesh Manoharan
  • Publication number: 20170156864
    Abstract: Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.
    Type: Application
    Filed: October 21, 2016
    Publication date: June 8, 2017
    Applicant: MVRx, Inc.
    Inventors: Robert T. Chang, John A. Macoviak, David A. Rahdert, Timothy R. Machold
  • Patent number: 9610161
    Abstract: An implant for supplementing, repairing, or replacing a native heart valve leaflet or leaflets provides a scaffold, which defines a pseudo-annulus. The implant further has at least two struts in generally oppositely spaced apart positions on the scaffold. The scaffold can be placed in an elastically loaded condition in a heart with the struts engaging tissue at or near the leaflet commissures of a heart valve annulus, to reshape the annulus for leaflet coaptation. The implant further provides a neoleaflet element coupled to the scaffold within pseudo-annulus, to provide a one-way valve function.
    Type: Grant
    Filed: September 8, 2011
    Date of Patent: April 4, 2017
    Assignee: MVRX, INC.
    Inventors: John A. Macoviak, Robert T. Chang, David A. Rahdert, Timothy R. Machold, Rick A. Soss