Patents by Inventor Timothy R. Sampson

Timothy R. Sampson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROBIOTIC TREATMENTS FOR PARKINSON'S DISEASE
    Publication number: 20240066074
    Abstract: Some embodiments herein relate generally to compositions comprising microbial organisms and/or components thereof for improving a neurological disorder, or symptoms associated with a neurological disorder, such as Parkinson's disease, and methods of using the same.
    Type: Application
    Filed: September 7, 2021
    Publication date: February 29, 2024
    Inventors: Anastasiya O. MOISEYENKO, Timothy R. SAMPSON, Sarkis K. MAZMANIAN
  • REGULATE GUT MICROBIOTA TO TREAT NEURODEGENERATIVE DISORDERS
    Publication number: 20240000862
    Abstract: Disclosed herein are methods and compositions that can be used to improve motor deficits and neuroinflammation in subjects in need, for example subjects suffering from neurodegenerative disorders (e.g., Parkinson's disease). Also disclosed are methods and compositions that can be used to diagnose neurodegenerative disorders, such as Parkinson's disease.
    Type: Application
    Filed: June 15, 2023
    Publication date: January 4, 2024
    Inventors: Sarkis K. Mazmanian, Timothy R. Sampson
  • Regulate gut microbiota to treat neurodegenerative disorders
    Patent number: 11707493
    Abstract: Disclosed herein are methods and compositions that can be used to improve motor deficits and neuroinflammation in subjects in need, for example subjects suffering from neurodegenerative disorders (e.g., Parkinson's disease). Also disclosed are methods and compositions that can be used to diagnose neurodegenerative disorders, such as Parkinson's disease.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: July 25, 2023
    Assignee: California Institute of Technology
    Inventors: Sarkis K. Mazmanian, Timothy R. Sampson
  • CAS9-nucleic acid complexes and uses related thereto
    Patent number: 11312945
    Abstract: This disclosure relates to Cas9-nucleic acid complexes and uses related thereto. In certain embodiments, the disclosure contemplates transgenic plants and animals genetically engineered to express Cas9-nucleic acid complexes disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing, diseases, conditions, cancer, viral infections or other pathogenic infection using vectors configured to express a Cas9-nucleic acid complex disclosed herein.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: April 26, 2022
    Assignee: Emory University
    Inventors: David S. Weiss, Arash Grakoui, Timothy R. Sampson, Aryn Alaine Price
  • CAS9-NUCLEIC ACID COMPLEXES AND USES RELATED THERETO
    Publication number: 20200354700
    Abstract: This disclosure relates to Cas9-nucleic acid complexes and uses related thereto. In certain embodiments, the disclosure contemplates transgenic plants and animals genetically engineered to express Cas9-nucleic acid complexes disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing, diseases, conditions, cancer, viral infections or other pathogenic infection using vectors configured to express a Cas9-nucleic acid complex disclosed herein.
    Type: Application
    Filed: July 10, 2019
    Publication date: November 12, 2020
    Inventors: David S. Weiss, Arash Grakoui, Timothy R. Sampson, Aryn Alaine Price
  • Cas9-nucleic acid complexes and uses related thereto
    Patent number: 10544405
    Abstract: This disclosure relates to Cas9-nucleic acid complexes and uses related thereto. In certain embodiments, the disclosure contemplates transgenic plants and animals genetically engineered to express Cas9-nucleic acid complexes disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing, diseases, conditions, cancer, viral infections or other pathogenic infection using vectors configured to express a Cas9-nucleic acid complex disclosed herein.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: January 28, 2020
    Assignee: Emory University
    Inventors: David S. Weiss, Arash Grakoui, Timothy R. Sampson, Aryn Alaine Price
  • REGULATE GUT MICROBIOTA TO TREAT NEURODEGENERATIVE DISORDERS
    Publication number: 20190388481
    Abstract: Disclosed herein are methods and compositions that can be used to improve motor deficits and neuroinflammation in subjects in need, for example subjects suffering from neurodegenerative disorders (e.g., Parkinson's disease). Also disclosed are methods and compositions that can be used to diagnose neurodegenerative disorders, such as Parkinson's disease.
    Type: Application
    Filed: May 22, 2017
    Publication date: December 26, 2019
    Inventors: Sarkis K. Mazmanian, Timothy R. Sampson
  • USE OF GUT MICROBIOTA IN THE DIAGNOSIS AND THERAPEUTICS OF PARKINSON'S DISEASE
    Publication number: 20180196044
    Abstract: Disclosed herein are methods and compositions that can be used to treat and diagnose parkinsonism, for example Parkinson's disease, and uses for the same.
    Type: Application
    Filed: February 9, 2018
    Publication date: July 12, 2018
    Inventors: Sarkis K. Mazmanian, Timothy R. Sampson
  • CAS9-NUCLEIC ACID COMPLEXES AND USES RELATED THERETO
    Publication number: 20150353905
    Abstract: This disclosure relates to Cas9-nucleic acid complexes and uses related thereto. In certain embodiments, the disclosure contemplates transgenic plants and animals genetically engineered to express Cas9-nucleic acid complexes disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing, diseases, conditions, cancer, viral infections or other pathogenic infection using vectors configured to express a Cas9-nucleic acid complex disclosed herein.
    Type: Application
    Filed: January 15, 2014
    Publication date: December 10, 2015
    Inventors: David S. Weiss, Arash Grakoui, Timothy R. Sampson, Aryn Alaine Price