Abstract: The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2”). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

Abstract: The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2”). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

Abstract: A private multiplexing cellular network for facilitating cellular communication for private mobile stations (MS's), public MS's, and hybrid MS's. The private multiplexing cellular network includes a multiplexing circuit coupled to its radio subsystem. The multiplexing circuit is in turn coupled to two A-interfaces: a private A-interface for coupling the private radio subsystem with the private Mobile Switching Center (MSC), and a public A-interface for coupling the private radio subsystem with the public MSC. Intelligence is also provided with the multiplexing circuit to decide, based on a number of parameters, whether the public MSC or the private MSC should handle a given service request.

Abstract: An apparatus for cross-connecting an end-to-end connection between an origination mobile station and a destination mobile station in a network of cross-connect nodes, which includes a call control circuit. The call control circuit includes a first circuit portion for receiving call control information from the origination mobile station and the destination mobile station and a second circuit portion for determining, responsive to receiving the call control information from the origination mobile station and the destination mobile station, an optimum end-to-end connection for cross-connecting the end-to-end connection through the network of cross-connect nodes. The optimum end-to-end connection represents a computed shortest communication route between the origination mobile station and the destination mobile station that satisfies resource requirements for cross-connecting the end-to-end connection.

Abstract: Our lead screw driver comprises a drive head for engaging and driving a complementary driver head portion of a threaded fastener, and a manipulator for positioning the drive head and a fastener engaged therewith for alignment of the same for driving the fastener into a pilot hole at a given location in a workpiece. A motor rotates the drive head and a lead screw arrangement is operatively coupled with the drive head for advancing the same at a given rate corresponding to the thread pitch of the fastener to be driven thereby so as to minimize stresses upon the material of the workpiece during the driving of the fastener. Preferably, a brake is operatively coupled to the manipulator and this brake is selectively actuatable for holding the manipulator against movement of the manipulator means, to hold the fastener aligned with the pilot hole while driving the fastener.