Patents by Inventor Timothy R. Willis

Timothy R. Willis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120016275
    Abstract: An apparatus for treating meibomian gland dysfunction caused by meibomian gland obstruction in order to restore the natural flow of secretion from the meibomian gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Application
    Filed: September 23, 2011
    Publication date: January 19, 2012
    Applicant: TearScience, Inc.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely
  • Publication number: 20120016450
    Abstract: In one embodiment, an apparatus for treating mammalian meibomian glands involves clearing the meibomian glands. The apparatus comprises a heater configured to apply a regulated heat to an eyelid containing the meibomian glands to a temperature adequate to melt obstructions in the meibomian glands to put the obstructions in a fluid or suspension (melted) state, and a controller maintaining the heat for a time period adequate to melt the obstructions. The glands can then be mechanically treated by a mechanical treatment applicator to express fluid from the glands by using a compressive force, wherein the treating is carried out either during the time period or after the time period but while the obstruction remains in a fluid state. Subsequent pharmacological treatment of the glands by use a pharmacological agent (topical or systemic) can then be used to assist in maintaining proper flow of lipids from the glands.
    Type: Application
    Filed: July 15, 2011
    Publication date: January 19, 2012
    Applicant: TEARSCIENCE, INC.
    Inventors: Donald R. Korb, Timothy R. Willis, Stephen M. Grenon
  • Patent number: 8083787
    Abstract: A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: December 27, 2011
    Assignee: TearScience, Inc.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely
  • Patent number: 8025689
    Abstract: A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: September 27, 2011
    Assignee: TearScience, Inc.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely
  • Patent number: 8007524
    Abstract: A method of treating meibomian gland dysfunction. Heat is applied to the tissue proximate the patient's meibomian glands to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force may also be applied to the tissue proximate the patient's meibomian glands to improve conductive heat transfer and reduce blood flow in the tissue that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands while reducing the amount of time to reached desired temperature levels and/or aid in reducing discomfort to the patient during treatment.
    Type: Grant
    Filed: January 17, 2008
    Date of Patent: August 30, 2011
    Assignee: TearScience, Inc.
    Inventors: Donald R. Korb, Stephen M. Grenon, Timothy R. Willis, John Martin Jans
  • Patent number: 7981145
    Abstract: In one embodiment consistent with the present invention a method of treating mammalian meibomian glands involves clearing the glands by applying a regulated heat to an eyelid containing the meibomian glands to a temperature adequate to melt obstructions in the meibomian glands to put the obstructions in a fluid or suspension (melted) state and maintaining the heat for a time period adequate to melt the obstructions. The glands can then be mechanically treated to express fluid from the glands, wherein the treating is carried out either during the time period or after the time period but while the obstruction remains in a fluid state. Subsequent pharmacological treatment of the glands by use a pharmacological agent (topical or systemic) can then be used to assist in maintaining proper flow of lipids from the glands. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: July 19, 2011
    Assignee: TearScience Inc.
    Inventors: Donald R. Korb, Timothy R. Willis, Stephen M. Grenon
  • Patent number: 7981146
    Abstract: A method of treating meibomian gland dysfunction. Heat is applied to the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. A force may also be applied to the outside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.
    Type: Grant
    Filed: January 17, 2008
    Date of Patent: July 19, 2011
    Assignee: TearScience Inc.
    Inventors: Donald R. Korb, Stephen M. Grenon, Timothy R. Willis, Benjamin Tyson Gravely
  • Patent number: 7981147
    Abstract: A method of treating meibomian gland dysfunction. Heat is applied to the outside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force may also be applied to the outside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions or occlusions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands while reducing the amount of time to reach desired temperature levels and/or aid in reducing discomfort to the patient during treatment.
    Type: Grant
    Filed: January 17, 2008
    Date of Patent: July 19, 2011
    Inventors: Donald R. Korb, Stephen M. Grenon, Timothy R. Willis, Benjamin Tyson Gravely
  • Publication number: 20110137214
    Abstract: A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Application
    Filed: February 11, 2011
    Publication date: June 9, 2011
    Applicant: TEARSCIENCE, INC.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely, Stephen M. Grenon
  • Publication number: 20110130729
    Abstract: A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Application
    Filed: February 11, 2011
    Publication date: June 2, 2011
    Applicant: TEARSCIENCE, INC.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely, Stephen M. Grenon
  • Publication number: 20110029075
    Abstract: A refractive intraocular lens (104) and method of locating the lens within the eye and attaching the lens to the iris. The refractive intraocular lens (104) may be attached via a staple (230), a fastener (312), anchor (412) or by the tip of the haptic (118). The intraocular lens (104) works in combination with the human crystalline lens to treat conditions selected from the group consisting of myopia, hyperopia and astigmatism.
    Type: Application
    Filed: October 8, 2010
    Publication date: February 3, 2011
    Inventors: Timothy R. Willis, Lyle E. Paul, Joseph Collin
  • Publication number: 20100292789
    Abstract: A refractive intraocular lens (104) and method of locating the lens within the eye and attaching the lens to the iris. The refractive intraocular lens (104) may be attached via a staple (230), a fastener (312), anchor (412) or by the tip of the haptic (118). The intraocular lens (104) works in combination with the human crystalline lens to treat conditions selected from the group consisting of myopia, hyperopia and astigmatism.
    Type: Application
    Filed: July 22, 2010
    Publication date: November 18, 2010
    Inventors: Timothy R. Willis, Lyle E. Paul, Joseph Collin
  • Publication number: 20100256552
    Abstract: A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Application
    Filed: June 23, 2010
    Publication date: October 7, 2010
    Applicant: TEARSCIENCE, INC.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely
  • Publication number: 20090043365
    Abstract: Embodiments include methods, apparatuses, and systems for reducing elevated intraocular pressure (IOP) in a patient to either prevent or treat open-angle glaucoma. Heat is applied to the trabecular meshwork in the patient's eye without damaging proteins in the trabecular meshwork. The application of heat to the trabecular meshwork has the effect of relaxing or loosening protein clogs or other inhibitors in the trabecular meshwork, which are either reducing or obstructing of the outflow of aqueous humor, thereby increasing the patient's IOP and causing ocular hypertension (OHT). By loosening or relaxing clogs or other inhibitors in the trabecular meshwork, the outflow path for aqueous humor is increased or restored, which can lower IOP and either prevent or treat glaucoma. Force may also be applied to the patient's eye to apply pressure to the trabecular meshwork to further assist in the loosening or relaxing of clogs or other inhibitors in the trabecular meshwork.
    Type: Application
    Filed: October 6, 2008
    Publication date: February 12, 2009
    Applicant: KOLIS SCIENTIFIC, INC.
    Inventors: Beth Friedland, Donald R. Korb, Steve Grenon, John Jans, Keith Gausmann, Timothy R. Willis
  • Publication number: 20080132978
    Abstract: A method of treating meibomian gland dysfunction. Heat is applied to the outside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force may also be applied to the outside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions or occlusions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands while reducing the amount of time to reach desired temperature levels and/or aid in reducing discomfort to the patient during treatment.
    Type: Application
    Filed: January 17, 2008
    Publication date: June 5, 2008
    Inventors: Donald R. Korb, Stephen M. Grenon, Timothy R. Willis, Benjamin Tyson Gravely
  • Publication number: 20080081999
    Abstract: In an illustrative embodiment, an apparatus for imaging a portion of a mammalian eyelid has an eye contact lenspiece configured to direct the light through an eyelid from posterior to anterior surface to thereby trans-illuminate the eyelid, when the light source illuminates the contact lens. An imaging device receives an image of the eyelid as it is trans-illuminated. Other methods and apparatus are presented in various embodiments, hence this abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
    Type: Application
    Filed: August 17, 2007
    Publication date: April 3, 2008
    Inventors: Benjamin T. Gravely, Stephen M. Grenon, Timothy R. Willis, John M. Jans, Donald R. Korb
  • Publication number: 20080081996
    Abstract: A method of evaluating dry eye in humans wherein the flow of naturally occurring secretion to the eye is reduced or stopped due to the presence of an obstruction of a meibomian gland in the eyelid involves applying a pressure to the eyelid that mimics pressure applied during blinking; and simultaneously imaging the glands to diagnose the condition of the meibomian gland. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
    Type: Application
    Filed: September 29, 2006
    Publication date: April 3, 2008
    Inventors: Stephen M. Grenon, Timothy R. Willis, Benjamin T. Gravely, Donald R. Korb
  • Patent number: 7008449
    Abstract: A refractive intraocular lens (104) and method of locating the lens within the eye and attaching the lens to the iris. The refractive intraocular lens (104) may be attached via a staple (230), a fastener (312), anchor (412) or by the tip of the haptic (118).
    Type: Grant
    Filed: August 16, 2004
    Date of Patent: March 7, 2006
    Inventors: Timothy R. Willis, Lyle E. Paul, Joseph Collin
  • Patent number: 6827738
    Abstract: A refractive intraocular lens and method of locating the lens within the eye and attaching the lens to the iris. The refractive intraocular lens may be attached via staples, a fastener or by the tip of the haptics.
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: December 7, 2004
    Inventors: Timothy R. Willis, Lyle E. Paul, Joseph Collin
  • Publication number: 20020103537
    Abstract: A refractive intraocular lens and method of locating the lens within the eye and attaching the lens to the iris. The refractive intraocular lens may be attached via staples, a fastener or by the tip of the haptics.
    Type: Application
    Filed: January 30, 2001
    Publication date: August 1, 2002
    Inventors: Timothy R. Willis, Lyle E. Paul, Joseph Collin