Patents by Inventor Timothy R. Zuffi

Timothy R. Zuffi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing a lipoprotein-poor concentrate of coagulation factors VII and VIIa
    Patent number: 4473553
    Abstract: There is disclosed a process for producing coagulation factors VII and VIIa in relatively high purity by contacting an aqueous preparation containing factors VII and VIIa with a lipoprotein binding adsorbent and separating the coagulation factors and other proteins therefrom, contacting the resulting lipoprotein-poor solution with a divalent metal salt adsorbent having selective affinity for calcium-binding coagulation factors and eluting the coagulation factors therefrom, and contacting the eluate with an anionic exchange resin and selectively eluting coagulation factors VII and VIIa therefrom by step or gradient elution techniques to obtain factors VII and VIIa free of other coagulation factors and other proteins.
    Type: Grant
    Filed: December 2, 1983
    Date of Patent: September 25, 1984
    Assignee: Miles Laboratories, Inc.
    Inventors: Timothy R. Zuffi, Nazreen Pancham
  • Purified immune serum globulin
    Patent number: 4272521
    Abstract: Existing and potential prekallikrein activator (PKA) can be removed from an immune serum globulin (ISG) solution using an ion exchange material to remove both existing PKA and a kallikrein-activatable precursor to PKA (Factor XII) found to be present in ISG solutions.
    Type: Grant
    Filed: July 16, 1979
    Date of Patent: June 9, 1981
    Assignee: Cutter Laboratories, Inc.
    Inventor: Timothy R. Zuffi