Abstract: The present invention is directed to a new fluoro-pyridinone hydroxamic acid phosphates and boronates of Formulae I, II and III wherein Q is selected from the group consisting of —P(O)(OH)2, —P(O)(OH)(O?M+), —P(O)(O?M+)2 and —P(O)(O?)2M2+; M+ at each occurrence is a pharmaceutically acceptable monovalent cation; and M2+ is a pharmaceutically acceptable divalent cation and their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: The invention relates to compounds of formula (I): or a salt thereof, wherein R1, G, L1, L2, L3, and Y are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are inhibitors of one, or both of, ?v?1 integrin and ?v?6 integrin that are useful for treating fibrosis such as in nonalcoholic steatohepatitis (NASH), idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

Abstract: A method for determining a mechanical angle to a radar target utilizing a multiple antenna radar altimeter is described. The method comprises receiving radar return signals at the multiple antennas, populating an ambiguity resolution matrix with the electrical phase angle computations, selecting a mechanical angle from the ambiguity resolution matrix that results in a least amount of variance from the electrical phase angle computations, and using at least one other variance calculation to determine a quality associated with the selected mechanical angle.

Abstract: A method for controlling a detonation altitude of a radar equipped munition is described. The method includes calculating a velocity of the munition while the munition is at an altitude greater than the desired detonation altitude, determining when the munition is at a reference altitude, and calculating a time representing when the vehicle will reach the desired detonation altitude based on the calculated velocity and determined reference altitude. The method also includes generating a fusing signal to detonate the munition after the calculated time has passed.

Abstract: A unit is described that is configured to control detonation of a munition such that the munition is detonated at a desired altitude. The unit includes a radar transmitter, a radar receiver that includes a radar range gate, and a sequencer. The sequencer is configured to receive a detonation altitude and set the range gate based on the received detonation altitude. The unit is also configured to output a detonation signal when radar return pulses received by the receiver aligned with gate delay pulses from the range gate.