Abstract: A heat exchanger positioned within an annular duct of a gas turbine engine is provided. The heat exchanger extends substantially continuously along the circumferential direction and defining a heat exchanger height equal to at least 10% of a duct height. An effective transmission loss (ETL) for the heat exchanger positioned within the annular duct is between 5 decibels and 1 decibels for an operating condition of the gas turbine engine. The heat exchanger includes a heat transfer section defining an acoustic length (Li), and wherein an Operational Acoustic Reduction Ratio (OARR) is greater than or equal to 0.75 to achieve the ETL at the operating condition.

Abstract: An inlet duct for a nacelle of a ducted fan engine includes an inlet portion having an inlet lip and a hardwall portion, a highlight plane defined at an upstream end of the inlet portion, and an acoustic liner downstream of the inlet portion, a hardwall-acoustic liner interface defined at an interface of the hardwall portion and the acoustic liner. The inlet portion and the acoustic liner are coupled at an inlet-acoustic liner interface extending circumferentially about an inner circumferential surface of the inlet duct. The inlet lip varies circumferentially and axially with respect to the highlight plane and the inlet centerline axis, and includes a plurality of inlet lip crests arranged along the highlight plane, and a plurality of inlet lip troughs arranged downstream of the highlight plane. The hardwall-acoustic liner interface extends circumferentially about the inner circumferential surface and is arranged axially parallel to the highlight plane.

Abstract: The present invention features a compound of formula I: or a pharmaceutically acceptable salt thereof, where R1, R2, R3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.

Abstract: Compounds of Formula (I): pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.

Abstract: The disclosure provides processes for synthesizing Compound I, and pharmaceutically acceptable salts thereof.

Abstract: Methods, systems and apparatus are provided for facilitating financial transactions using an IC type financial card presented at a terminal. A requested transaction for monetary value is processed via a first transaction type. If the transaction is successful, monetary value (such as cash or a monetary value ticket or receipt) is dispensed to the user. If unsuccessful, the card is not ejected and the transaction is processed via a second transaction type. The first transaction type might be a PIN based ATM or ticket transaction and the second transaction type might be a signature based transaction.

Abstract: An inlet duct for a nacelle of a ducted fan engine includes an inlet portion at an upstream end of the inlet duct, an acoustic liner arranged downstream of the inlet portion, and a fan section arranged downstream of the acoustic liner. The inlet portion and the acoustic liner are coupled together at an inlet-acoustic liner interface extending circumferentially about the inner surface of the inlet duct, and the acoustic liner and the fan section are coupled together at a fan section hardwall-acoustic liner interface extending circumferentially about the inner surface of the inlet duct. At least one of the acoustic liner, the inlet-acoustic liner interface, and the fan section hardwall-acoustic liner interface having a structure that circumferentially alters a magnitude and a phase of an acoustic wave reflection of the inlet duct to attenuate flutter bite of a fan.

Abstract: A system configured to transfer an individual between an area and a toilet within a lavatory includes a base, one or more rollers coupled to the base, and a seating assembly coupled to the base. The seating assembly includes a backrest, a toilet overlay seat configured to be disposed over the toilet, and a seat cover that is movable between a covering position over the toilet overlay seat, and a lavatory use position in which the toilet overlay seat is exposed. A counterbalance is coupled to one or both of the base or the seating assembly. The counterbalance is moveable between a stowed position and a deployed position in relation to the toilet.

Abstract: An acoustic core may include an array of resonant cells configured as a plurality of resonant cell groups. The resonant cell groups may include a plurality of resonant cells configured as a partitioned resonant cell that include a converging resonant cell and a diverging resonant cell. The converging resonant cell and the diverging resonant cell may be defined by a plurality of cell walls integrally formed with one another and a partition integrally formed with the plurality of cell walls. The partition may at least partially delimit the converging resonant cell from the diverging resonant cell. The converging resonant cell may define an upper resonant space delimited by the partition and a top face of the array of resonant cells. The diverging resonant cell may define a lower resonant space delimited by the partition and a bottom face of the array of resonant cells.

Abstract: The present disclosure relates to cantilevered imaging modality wearable optical systems that provide for optimal ergonomics coupled with vision enhancement and vision magnification. Methods of use, devices, and kits are also contemplated.

Abstract: An improved financial terminal automatically reconfigures into different financial processing terminal types. In one embodiment, the terminal comprises a housing; a card reader configured to accept at least a portion of a card having an integrated circuit; at least one display; at least one processor; and at least one memory configured to store machine readable code, the machine readable code comprising a first kernel corresponding to a first transaction type and a second kernel corresponding to a second transaction type.

Abstract: A system configured to transfer an individual between an area and a toilet within a lavatory includes a base, one or more rollers coupled to the base, and a seating assembly coupled to the base. The seating assembly includes a backrest, a toilet overlay seat configured to be disposed over the toilet, and a seat cover that is movable between a covering position over the toilet overlay seat, and a lavatory use position in which the toilet overlay seat is exposed. A counterbalance is coupled to one or both of the base or the seating assembly. The counterbalance is moveable between a stowed position and a deployed position in relation to the toilet.

Abstract: A method for predicting progress of a code development project, comprising: monitoring behavior of a plurality of software developers through interaction with at least an integrated development environment; providing a predictive model of the code development project adapted to predict a future status of the code development project; and outputting a prediction dependent on a status of the code development project at a future time, the interaction comprising: exploration events comprising browsing source code for understanding or investigation; coding events comprising actively modifying source code; debugging events comprising interacting with a debugger stepping through code in a debugging phase; and testing events comprising coding or running unit tests and test automation.

Abstract: An agricultural implement includes a main frame, a first frame member assembly coupled to the main frame, and a first plurality of discs coupled to the first frame member assembly. The agricultural implement also includes a first linkage assembly coupled to the first frame member assembly. The agricultural implement further includes a first lateral adjustment mechanism coupled to the first frame member assembly and configured to actuate the first linkage assembly to change a first lateral position of the first plurality of discs relative to at least one other plurality of discs coupled to the main frame or relative to a center line of the main frame, the center line being parallel to a direction of travel of the agricultural implement.

Abstract: A gas turbine engine comprises a fan, a core turbine engine coupled to the fan, a fan case housing the fan and the core turbine engine, a plurality of outlet guide vanes extending between the core turbine engine and the fan case, and an acoustic spacing. The fan comprises a plurality of fan blades that define a fan diameter and a BEAL. The fan case comprises an inlet and an inlet length between the inlet and the fan. The acoustic spacing comprises a distance between the fan and the plurality of outlet guide vanes, and in combination with the BEAL determines an acoustic spacing ratio of the gas turbine engine.

Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) having core structure (I), pharmaceutical compositions containing at least one such modulator, methods of treatment of CFTR mediated diseases, including cystic fibrosis, using such modulators and pharmaceutical compositions, combination pharmaceutical compositions and combination therapies employing those modulators, and processes and intermediates for making such modulators.

Abstract: A gas turbine engine comprises a fan, a core turbine engine coupled to the fan, a fan case housing the fan and the core turbine engine, a plurality of outlet guide vanes extending between the core turbine engine and the fan case, and an acoustic spacing. The fan comprises a plurality of fan blades that define a fan diameter and a BEAL. The fan case comprises an inlet and an inlet length between the inlet and the fan. The acoustic spacing comprises a distance between the fan and the plurality of outlet guide vanes, and in combination with the BEAL determines an acoustic spacing ratio of the gas turbine engine.

Abstract: An acoustic core may include an array of resonant cells configured as a plurality of resonant cell groups. The resonant cell groups may include a plurality of resonant cells configured as a partitioned resonant cell that include a converging resonant cell and a diverging resonant cell. The converging resonant cell and the diverging resonant cell may be defined by a plurality of cell walls integrally formed with one another and a partition integrally formed with the plurality of cell walls. The partition may at least partially delimit the converging resonant cell from the diverging resonant cell. The converging resonant cell may define an upper resonant space delimited by the partition and a top face of the array of resonant cells. The diverging resonant cell may define a lower resonant space delimited by the partition and a bottom face of the array of resonant cells.

Abstract: A system for providing AC or DC power, for charging or powering electrical/electronic devices that are being used whilst the device is located at, around or within, an item of furniture which is defined as an item that has no local connection point to a mains AC wired power supply of an environment. The system is provided by a series of modules, at least some of which are based around a single mechanical fixation system, thereby allowing the furniture designer or manufacturer to implement a common mechanical fixing system and choose from a variety of modules to create the electrical system so desired. Modules within the system include a at least one battery module plus modules such as a Power Supply Unit (PSU), an AC or DC power in-feed connection point, DC power provision points, inverter, AC power provision points, switches, electrical protection devices and/or power control devices.

Abstract: Methods, systems and apparatus are provided for facilitating financial transactions using an IC type financial card presented at a terminal. A requested transaction for monetary value is processed via a first transaction type. If the transaction is successful, monetary value (such as cash or a monetary value ticket or receipt) is dispensed to the user. If unsuccessful, the card is not ejected and the transaction is processed via a second transaction type. The first transaction type might be a PIN based ATM or ticket transaction and the second transaction type might be a signature based transaction.