Patents by Inventor Timothy Robin JAMES

Timothy Robin JAMES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220226318
    Abstract: The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies, wherein the disease is facioscapulohumeral muscular dystrophy (FSHD). It also relates to use of such compounds, or to methods of use of such compounds.
    Type: Application
    Filed: January 13, 2022
    Publication date: July 21, 2022
    Applicant: Facio Intellectual Property B.V.
    Inventors: Joris De Maeyer, Marcus Geese, Martin Schneider, Sebastian Monecke, Alexander Kaever, Monika Ermann, Timothy Robin James
  • Publication number: 20210177847
    Abstract: The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies. It also relates to use of such compounds, or to methods of use of such compounds.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 17, 2021
    Applicant: Facio Intellectual Property B.V.
    Inventors: Joris De Maeyer, Marcus Geese, Martin Schneider, Sebastian Monecke, Alexander Kaever, Monika Ermann, Timothy Robin James
  • Patent number: 10973820
    Abstract: The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies, wherein the disease is facioscapulohumeral muscular dystrophy (FSHD). It also relates to use of such compounds, or to methods of use of such compounds.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: April 13, 2021
    Assignee: Facio Intellectual Property B.V.
    Inventors: Joris de Maeyer, Marcus Geese, Martin Schneider, Sebastian Monecke, Alexander Kaever, Monika Ermann, Timothy Robin James
  • Patent number: 10472341
    Abstract: The present invention relates to bicyclic tetrahydrothiazepine of formula (I), wherein R1 to R3, X1, X2 and R18 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising such compounds as well as their use as medicaments, especially in methods for the treatment or prevention of a neoplastic and/or infectious disease and in vitro methods.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: November 12, 2019
    Assignees: APEIRON BIOLOGICS AG, EVOTEC SE
    Inventors: Monika Ermann, Guenther Lametschwandtner, Patricia Leonie Amouzegh, Russell Stuart Craft, Thomas Hanke, Timothy Robin James, Severine Danielle Jones, Hans Loibner, Pui Leng Loke, Ina Sternberger, Anton Stuetz, Roland Wehr, Mark Whittaker
  • Publication number: 20190175596
    Abstract: The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies, wherein the disease is facioscapulohumeral muscular dystrophy (FSHD). It also relates to use of such compounds, or to methods of use of such compounds.
    Type: Application
    Filed: December 12, 2018
    Publication date: June 13, 2019
    Applicant: Facio Intellectual Property B.V.
    Inventors: Joris de Maeyer, Marcus Geese, Martin Schneider, Sebastian Monecke, Alexander Kaever, Monika Ermann, Timothy Robin James
  • Publication number: 20180170888
    Abstract: The present invention relates to bicyclic tetrahydrothiazepine of formula (I), wherein R1 to R3, X1, X2 and R18 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising such compounds as well as their use as medicaments, especially in methods for the treatment or prevention of a neoplastic and/or infectious disease and in vitro methods.
    Type: Application
    Filed: February 29, 2016
    Publication date: June 21, 2018
    Inventors: Monika ERMANN, Guenther LAMETSCHWANDTNER, Patricia Leonie AMOUZEGH, Russell Stuart CRAFT, Thomas HANKE, Timothy Robin JAMES, Severine Danielle JONES, Hans LOIBNER, Pui Leng LOKE, Ina STERNBERGER, Anton STUETZ, Roland WEHR, Mark WHITTAKER