Patents by Inventor Timothy Sampson

Timothy Sampson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11147792
    Abstract: The present disclosure provides methods and compositions for the prevention, amelioration, or alleviation of one or more neurological disorders associated with microbially-induced amyloid formation. Methods of inhibiting, ameliorating, reducing the likelihood, delaying the onset of, treating, or preventing an amyloid disorder are disclosed. Methods of identifying compounds capable of inhibiting the formation of microbially-induced amyloid fibrils are disclosed.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: October 19, 2021
    Assignees: AXIAL THERAPEUTICS, INC., CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Timothy Sampson, Sarkis Mazmanian, Anthony Stewart Campbell
  • Publication number: 20200163933
    Abstract: The present disclosure provides methods and compositions for the prevention, amelioration, or alleviation of one or more neurological disorders associated with microbially-induced amyloid formation. Methods of inhibiting, ameliorating, reducing the likelihood, delaying the onset of, treating, or preventing an amyloid disorder are disclosed. Methods of identifying compounds capable of inhibiting the formation of microbially-induced amyloid fibrils are disclosed.
    Type: Application
    Filed: May 14, 2018
    Publication date: May 28, 2020
    Inventors: Timothy Sampson, Sarkis Mazmanian, Anthony Stewart Campbell
  • Patent number: 10422204
    Abstract: A system and method for stimulating hydrocarbon production from a wellbore that perforates the formation around the wellbore in strategic locations so that fractures can be formed in the formation having specific orientations. The system includes deep penetration perforators that extend past a portion of the formation adjacent the wellbore having locally high internal stresses (a stress cage); and big hole perforators that form perforations with a larger entrance diameter. The perforators form perforations in the formation that are axially consolidated along the wellbore. After perforating, the wellbore is hydraulically fractured with high pressure fluid, which creates fractures in a formation surrounding the wellbore that extend radially outward from the perforations. Creating perforations that are axially consolidated reduces the chances of forming competing fractures in the formation during fracturing.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: September 24, 2019
    Assignee: BAKER HUGHES INCORPORATED
    Inventors: Timothy Sampson, Stephen Zuklic, Khaled Gasmi, Brent W. Naizer, Rajani Satti, Scott G. Nelson, Harold D. Brannon, Jason McCann, James N. Gilliat, Juan C. Flores
  • Publication number: 20170328134
    Abstract: A method and system for downhole operations that includes an energetic material with a reduced sensitivity to temperature, and a temperature rating that is higher than other energetic materials. Downhole tools that use energetic material thus can have a higher temperature rating with the reduced sensitivity energetic material. One embodiment of the energetic material includes an energetic heterocycle compound, such as 2,6-diamino-3,5-dinitropyrazine-1-oxide.
    Type: Application
    Filed: May 12, 2017
    Publication date: November 16, 2017
    Applicant: Baker Hughes Incorporated
    Inventors: Timothy Sampson, Gasmi Khaled, Stephen Zuklic, Jason McCann, William Harvey, David Betancourt, Charles McClean, Mark Sloan
  • Publication number: 20170167233
    Abstract: A system and method for stimulating hydrocarbon production from a wellbore that perforates the formation around the wellbore in strategic locations so that fractures can be formed in the formation having specific orientations. The system includes deep penetration perforators that extend past a portion of the formation adjacent the wellbore having locally high internal stresses (a stress cage); and big hole perforators that form perforations with a larger entrance diameter. The perforators form perforations in the formation that are axially consolidated along the wellbore. After perforating, the wellbore is hydraulically fractured with high pressure fluid, which creates fractures in a formation surrounding the wellbore that extend radially outward from the perforations. Creating perforations that are axially consolidated reduces the chances of forming competing fractures in the formation during fracturing.
    Type: Application
    Filed: December 14, 2015
    Publication date: June 15, 2017
    Inventors: Timothy Sampson, Stephen Zuklic, Khaled Gasmi, Brent W. Naizer, Rajani Satti, Scott G. Nelson, Harold D. Brannon, Jason McCann, James N. Gilliat, Juan C. Flores
  • Patent number: 9068441
    Abstract: A method and device for fracturing a subterranean formation by projecting a bullet assembly into the formation and then reacting energetic material within the bullet assembly. The bullet assembly can be part of a charge device that is in a perforating gun. A delay fuse can be included so the energetic material reaction begins after the bullet assembly reaches the end of its travel in the formation.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: June 30, 2015
    Assignee: Baker Hughes Incorporated
    Inventor: Timothy Sampson
  • Patent number: 9027378
    Abstract: A digital manufacturing system comprises a build chamber, a build platform disposed within the build chamber, at least one extrusion line configured to heat a metal-based alloy up to a temperature between solidus and liquidus temperatures of the metal-based alloy, a deposition head disposed within the build chamber and configured to deposit the heated metal-based alloy onto the build platform in a predetermined pattern, an umbilical having a first end located outside of the build chamber and a second end connected to the deposition head, and at least one gantry assembly configured to cause relative motion between the build platform and the deposition head within the build chamber, where the at least one gantry assembly comprises a motor disposed outside of the build chamber.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: May 12, 2015
    Assignee: Stratasys, Inc.
    Inventors: S. Scott Crump, J. Samuel Batchelder, Timothy Sampson, Robert Zinniel, John Barnett
  • Publication number: 20130056212
    Abstract: A method and device for fracturing a subterranean formation by projecting a bullet assembly into the formation and then reacting energetic material within the bullet assembly. The bullet assembly can be part of a charge device that is in a perforating gun. A delay fuse can be included so the energetic material reaction begins after the bullet assembly reaches the end of its travel in the formation.
    Type: Application
    Filed: September 2, 2011
    Publication date: March 7, 2013
    Applicant: BAKER HUGHES INCORPORATED
    Inventor: Timothy Sampson
  • Patent number: 8347962
    Abstract: A shaped charge assembly for use in a perforating gun that further comprises a charge carrier, and gun housing. The charge carrier substantially encapsulates the closed portion of the shaped charge and extends from the outer periphery of the shaped charge to the inner diameter of the associated gun housing. Encapsulating the shaped charge substantially reduces the introduction of debris into the wellbore resulting from detonation of the perforating gun shaped charges. The charge carrier can include a multiplicity of shaped charges therein.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: January 8, 2013
    Assignee: Baker Hughes Incorporated
    Inventors: Timothy Sampson, Anna Schwartz, Mark Sloan, Avigdor Hetz, Jason McCann, Meir Mayseless
  • Patent number: 8245757
    Abstract: A support material for use with a digital manufacturing system, the support material comprising at least one inorganic ionic compound and is configured to be deposited with the digital manufacturing system using a layer-based additive technique to form a support structure for supporting at least one overhanging region of a three-dimensional model built with the digital manufacturing system.
    Type: Grant
    Filed: February 2, 2010
    Date of Patent: August 21, 2012
    Assignee: Stratasys, Inc.
    Inventors: S. Scott Crump, J. Samuel Batchelder, Timothy Sampson, John Barnett
  • Publication number: 20120168162
    Abstract: A shaped charge assembly for use in a perforating gun that further comprises a charge carrier, and gun housing. The charge carrier substantially encapsulates the closed portion of the shaped charge and extends from the outer periphery of the shaped charge to the inner diameter of the associated gun housing. Encapsulating the shaped charge substantially reduces the introduction of debris into the wellbore resulting from detonation of the perforating gun shaped charges. The charge carrier can include a multiplicity of shaped charges therein.
    Type: Application
    Filed: July 13, 2006
    Publication date: July 5, 2012
    Inventors: Timothy Sampson, Anna Schwartz, Mark Sloan, Avigdor Hetz, Jason McCann
  • Publication number: 20110232855
    Abstract: A digital manufacturing system comprises a build chamber, a build platform disposed within the build chamber, at least one extrusion line configured to heat a metal-based alloy up to a temperature between solidus and liquidus temperatures of the metal-based alloy, a deposition head disposed within the build chamber and configured to deposit the heated metal-based alloy onto the build platform in a predetermined pattern, an umbilical having a first end located outside of the build chamber and a second end connected to the deposition head, and at least one gantry assembly configured to cause relative motion between the build platform and the deposition head within the build chamber, where the at least one gantry assembly comprises a motor disposed outside of the build chamber.
    Type: Application
    Filed: April 8, 2011
    Publication date: September 29, 2011
    Applicant: STRATASYS, INC.
    Inventors: S. Scott Crump, J. Samuel Batchelder, Timothy Sampson, Robert L. Zinniel, John Barnett
  • Patent number: 7942987
    Abstract: A digital manufacturing system comprises a build chamber, a build platform disposed within the build chamber, at least one extrusion line configured to heat a metal-based alloy up to a temperature between solidus and liquidus temperatures of the metal-based alloy, a deposition head disposed within the build chamber and configured to deposit the heated metal-based alloy onto the build platform in a predetermined pattern, an umbilical having a first end located outside of the build chamber and a second end connected to the deposition head, and at least one gantry assembly configured to cause relative motion between the build platform and the deposition head within the build chamber, where the at least one gantry assembly comprises a motor disposed outside of the build chamber.
    Type: Grant
    Filed: June 24, 2008
    Date of Patent: May 17, 2011
    Assignee: Stratasys, Inc.
    Inventors: S. Scott Crump, J. Samuel Batchelder, Timothy Sampson, Robert L. Zinniel, John Barnett
  • Patent number: 7770662
    Abstract: A shaped charge assembly for use in a perforating gun that comprises a shaped charge holder, two or more shaped charges, slots formed to receive the shaped charges, and an impedance barrier disposed between adjacent shaped charges. The impedance barrier can comprise a gap formed in the shaped charge holder, where the impedance barrier runs across the shaped charge holder. The impedance barrier can be a void formed on the surface of the shaped charge holder, or can include shock attenuating material therein, such as wood, cork, cotton, polymeric materials, and combinations thereof, to name a few.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: August 10, 2010
    Assignee: Baker Hughes Incorporated
    Inventors: William Harvey, Meir Mayseless, Anna Schwartz, Timothy Sampson, Mark Sloan, Jason McCann, Avigdor Hetz
  • Publication number: 20100193998
    Abstract: A support material for use with a digital manufacturing system, the support material comprising at least one inorganic ionic compound and is configured to be deposited with the digital manufacturing system using a layer-based additive technique to form a support structure for supporting at least one overhanging region of a three-dimensional model built with the digital manufacturing system.
    Type: Application
    Filed: February 2, 2010
    Publication date: August 5, 2010
    Applicant: STRATASYS, INC.
    Inventors: S. Scott Crump, J. Samuel Batchelder, Timothy Sampson, John Barnett
  • Publication number: 20090314391
    Abstract: A digital manufacturing system comprises a build chamber, a build platform disposed within the build chamber, at least one extrusion line configured to heat a metal-based alloy up to a temperature between solidus and liquidus temperatures of the metal-based alloy, a deposition head disposed within the build chamber and configured to deposit the heated metal-based alloy onto the build platform in a predetermined pattern, an umbilical having a first end located outside of the build chamber and a second end connected to the deposition head, and at least one gantry assembly configured to cause relative motion between the build platform and the deposition head within the build chamber, where the at least one gantry assembly comprises a motor disposed outside of the build chamber.
    Type: Application
    Filed: June 24, 2008
    Publication date: December 24, 2009
    Applicant: Stratasys, Inc.
    Inventors: S. Scott Crump, J. Samuel Batchelder, Timothy Sampson, Robert L. Zinniel, John Barnett
  • Patent number: 7599735
    Abstract: The invention relates to a method for positioning electrodes in an electrode array comprising a plurality of electrodes for central nervous system (CNS) monitoring from the forehead of a subject. In order to enable efficient detection of eye movement artifacts with a minimum number of electrodes, first and second electrodes are positioned so that eye movement in one of the horizontal or vertical directions causes a negligible overall voltage change between the first and second electrodes and at least a third electrode is positioned so that eye movement in the other of said horizontal and vertical directions causes a high potential difference between the third electrode and an auxiliary electrode, wherein the auxiliary electrode is one of the electrodes in a set comprising one of the first and second electrodes and a fourth electrode.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: October 6, 2009
    Assignee: General Electric Company
    Inventors: Hanna E. Viertiƶ-Oja, Timothy Sampson
  • Publication number: 20070255164
    Abstract: The invention relates to a method for positioning electrodes in an electrode array comprising a plurality of electrodes for central nervous system (CNS) monitoring from the forehead of a subject. In order to enable efficient detection of eye movement artifacts with a minimum number of electrodes, first and second electrodes are positioned so that eye movement in one of the horizontal or vertical directions causes a negligible overall voltage change between the first and second electrodes and at least a third electrode is positioned so that eye movement in the other of said horizontal and vertical directions causes a high potential difference between the third electrode and an auxiliary electrode, wherein the auxiliary electrode is one of the electrodes in a set comprising one of the first and second electrodes and a fourth electrode.
    Type: Application
    Filed: December 22, 2005
    Publication date: November 1, 2007
    Inventors: Hanna Viertio-Oja, Timothy Sampson
  • Patent number: 7237486
    Abstract: Disclosed herein is a shaped charge assembly for use in a perforating gun. The shaped charge assembly includes a shaped charge combined with a longitudinal spine extending along a portion of a perforating gun barrel. The shaped charge can be secured to the spine with a retaining shell. A bushing is included between the outer radius of the casing the retaining shell. The bushing serves to absorb shock during detonation of the shaped charge and to help in orienting the shaped charges.
    Type: Grant
    Filed: April 8, 2004
    Date of Patent: July 3, 2007
    Assignee: Baker Hughes Incorporated
    Inventors: William Myers, Jr., Timothy Sampson, James W. Reese, Avigdor Hetz
  • Patent number: 7237487
    Abstract: Disclosed herein is a reinforcing system for a shaped charge assembly for use in a perforating gun. The shaped charge assembly includes a shaped charge combined with a longitudinal reinforcing system extending along a portion of a perforating gun barrel. The reinforcing system comprises a spine with a recess formed to receive the shaped charge of a perforating gun. The reinforcing system further comprises a compression zone coaxially disposed around a portion of the shaped charge. The compression zone is formed between a bushing and a retaining shell that also coaxially circumscribe a portion of the shaped charge and on one of their respective ends connect to the spine.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: July 3, 2007
    Assignee: Baker Hughes Incorporated
    Inventors: William Myers, Jr., Timothy Sampson, Avigdor Hetz