Abstract: The present invention is directed to a personal composition comprising a) a strobilurin; b) a 2-pyridinol-N-oxide material wherein the ratio of a:b is from about 10:1 to about 1:20; wherein there is a synergistic anti-inflammatory/cellular stress activity.

Abstract: Monitoring the brake performance of a brake system of a machine (vehicle 11) by determining a brake delay between input of a request for a brake engagement of the brake system and brake system effectuating the brake engagement. The brake delay determination provides for capturing delay produced by communication of the input from a brake input, actuation of an input to brake system performance, processing of operation of the brake system, and operation of the brake/retardation components of the brake system with respect to the machine's wheels. For autonomous machines, brake delay may be measured periodically and used in monitoring brake system performance.

Abstract: A control system is used to monitor the brake performance of a machine by detecting a brake engagement for decelerating the machine. If a wheel lock of at least one wheel of the machine is detected during the brake engagement and resulting from the brake engagement whilst the machine is moving, the data collected by the control system for brake engagement is rejected or the generation of brake performance data associated with the brake engagement is prevented. The machine may be an autonomous machine and the brake engagement may be routinely scheduled to provide for brake system monitoring while the machine is in operation.

Abstract: Monitoring the brake performance of a brake system of a machine and a control systems for performing such monitoring. The machine's brake system is monitored by detecting a brake engagement for decelerating the machine. When a brake engagement is detected, a parasitic loss decelerating the machine during the brake engagement is determined. The parasitic loss is used to predict deceleration of the machine during the brake engagement Brake performance of the brake system of the machine is processed from the predicted deceleration.

Abstract: A machine includes: an axle having wheels mounted to it; a brake system configured to provide service braking to the wheels; a brake pedal operatively connected to the brake system to provide a braking power to the wheels in proportion to the position of the brake pedal; a pedal sensor operatively connected to the brake pedal to sense the position of the brake pedal; a retarder system configured to selectively slow the wheels down; a speed sensor operatively connected to the machine to detect a speed associated with the machine; a controller operatively connected to the speed sensor, brake pedal position sensor, and retarder system wherein the controller is configured to operate the retarder system based on signals received from the speed sensor and brake pedal position sensor. A method for providing an indication to an operator may also be included.

Abstract: A rollover prevention system for a machine is disclosed. The rollover prevention system may include an inertial measurement unit (IMU) configured to detect a discharge event of a payload material from the machine and measure a body angle of the machine. The rollover prevention system may further include a controller in communication with the IMU. The controller may be configured to determine an angle of repose of the machine based on the detected discharge event and the measured body angle.

Abstract: A method for implementing and canceling an automatic operation of a body of a machine includes receiving a selection of an automatic setting according to a first operation of a hoist mode actuator, determining an activation state of the automatic setting, causing an automatic operation of an engine of the machine to adjust an idle level of the engine and an automatic operation of a hoist system to move the body in a first direction to a first position. The method includes canceling the automatic operation of the engine and the automatic operation of the hoist system and controlling the idle level of the engine according to operations of a throttle, the hoist system to move the body according to the idle level of the engine and respective directions of the second operation the hoist mode actuator and subsequent operations of the hoist mode actuator.

Abstract: A method for implementing an operation of a body of a machine includes receiving data indicating an operation of a positioning mode actuator to facilitate movement of the body from a first position, determining activation state of a multi-auto mode to actuate a first auto lower mode to operate a hoist system to lower the body automatically and a first auto raise mode to operate the hoist system to raise the body automatically. The method includes determining the first auto lower mode is selected according to the data indicating the operation of the positioning mode actuator, and causing a hoist system to actively lower the body from the first position to a second position and passively lower the body from the second position to a third position, independent of the activation state of the multi-auto mode.

Abstract: A method for implementing an operation of a body of a machine includes receiving data indicating an operation of a positioning mode actuator to facilitate movement of the body from a first position, determining activation state of a multi-auto mode to actuate a first auto lower mode to operate a hoist system to lower the body automatically and a first auto raise mode to operate the hoist system to raise the body automatically. The method includes determining the first auto lower mode is selected according to the data indicating the operation of the positioning mode actuator, and causing a hoist system to actively lower the body from the first position to a second position and passively lower the body from the second position to a third position, independent of the activation state of the multi-auto mode.

Abstract: A rollover prevention system for a machine is disclosed. The rollover prevention system may include an inertial measurement unit (IMU) configured to detect a discharge event of a payload material from the machine and measure a body angle of the machine. The rollover prevention system may further include a controller in communication with the IMU. The controller may be configured to determine an angle of repose of the machine based on the detected discharge event and the measured body angle.

Abstract: A method for implementing and canceling an automatic operation of a body of a machine includes receiving a selection of an automatic setting according to a first operation of a hoist mode actuator, determining an activation state of the automatic setting, causing an automatic operation of an engine of the machine to adjust an idle level of the engine and an automatic operation of a hoist system to move the body in a first direction to a first position. The method includes canceling the automatic operation of the engine and the automatic operation of the hoist system and controlling the idle level of the engine according to operations of a throttle, the hoist system to move the body according to the idle level of the engine and respective directions of the second operation the hoist mode actuator and subsequent operations of the hoist mode actuator.

Abstract: A machine includes: an axle having wheels mounted to it; a brake system configured to provide service braking to the wheels; a brake pedal operatively connected to the brake system to provide a braking power to the wheels in proportion to the position of the brake pedal; a pedal sensor operatively connected to the brake pedal to sense the position of the brake pedal; a retarder system configured to selectively slow the wheels down; a speed sensor operatively connected to the machine to detect a speed associated with the machine; a controller operatively connected to the speed sensor, brake pedal position sensor, and retarder system wherein the controller is configured to operate the retarder system based on signals received from the speed sensor and brake pedal position sensor. A method for providing an indication to an operator may also be included.

Abstract: Presently described is a guanosine-rich polynucleotide molecule with therapeutic utility for treating or preventing the growth of cancerous cells. In addition, a method of retarding cell cycle progression and inducing apoptosis in tumor cells using synthetic oligonucleotides is also described.

Abstract: A household laundry appliance is provided for washing and drying individual pieces of laundry. The appliance includes a bin for holding laundry, wash and dry stations, and a robotic feeder mechanism to automatically convey laundry from the bin to the processing stations. The wash stations include a spray station for spraying the garments with a cleaning solution, and an ultrasonic station for applying ultrasonic vibrations to the garments. Rinse and extraction stations are provided upstream from the drying station to rinse the garments and then extract water from the garments. The garments are continuously transported through the appliance by a series of mesh conveyor belts between which the garments are sandwiched. The drying station includes fans for blowing heated air past the clothing to drive moisture out of the clothing. The temperature and velocity of the air may be adjusted to accommodate different garment materials and dampness.