Patents by Inventor Timothy Stone
Timothy Stone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12462942Abstract: A container includes a two-piece lid, a base, and an O-ring. The two-piece lid includes a plate and a connector including a first leg with internal threads and a second leg. The base defines a cavity with an open end and a closed end and includes a collar with external threads. The O-ring is configured to form a seal between the two-piece lid and the base. The internal threads on the first leg of the connector engage the external threads of the collar responsive to rotation of the two-piece lid relative to the base. The second leg of the connector drives the plate towards the base responsive to the internal threads on the first leg of the connector engaging the external threads of the collar. The O-ring forms the seal as the internal threads on the first leg of the connector engage the external threads of the collar.Type: GrantFiled: February 14, 2023Date of Patent: November 4, 2025Assignee: Triad National Security, LLCInventors: Timothy Stone, Oka Jude
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Publication number: 20240274309Abstract: A container includes a two-piece lid, a base, and an O-ring. The two-piece lid includes a plate and a connector including a first leg with internal threads and a second leg. The base defines a cavity with an open end and a closed end and includes a collar with external threads. The O-ring is configured to form a seal between the two-piece lid and the base. The internal threads on the first leg of the connector engage the external threads of the collar responsive to rotation of the two-piece lid relative to the base. The second leg of the connector drives the plate towards the base responsive to the internal threads on the first leg of the connector engaging the external threads of the collar.Type: ApplicationFiled: February 14, 2023Publication date: August 15, 2024Inventors: Timothy Stone, Oka Jude
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Patent number: 7511155Abstract: A matched set of fluorescent dyes is provided, wherein each dye of the set is capable of covalent attachment to a protein and wherein each of the dyes has a molecular structure and a charge that is matched one with the other, such that relative electrophoretic mobility of a protein labeled with one dye of the set is the same as the electrophoretic mobility of the protein labeled with a different dye of the set. The matched set comprises at least two different fluorescent dyes of formula: wherein n is 1, 2, or 3; Z1 and Z2 independently represent the carbon atoms necessary to complete a phenyl or naphthyl ring system; one of groups R1 and R2 is a target bonding group; remaining group R1 or R2 is selected from —(CH2)4—W or —(CH2)r—H; group R3 is hydrogen, except when either R1 or R2 is —(CH2)r—H, in which case R3 is W; and W is selected from sulphonic acid and sulphonate.Type: GrantFiled: July 8, 2002Date of Patent: March 31, 2009Assignee: GE Healthcare UK LimitedInventors: Karen Williams, Timothy Stone, Adrian Christopher Simmonds, Alison Claire Sweet, Susan Janet Fowler
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Publication number: 20050233462Abstract: A matched set of fluorescent dyes is provided, wherein each dye of the set is capable of covalent attachment to a protein and wherein each of the dyes has a molecular structure and a charge that is matched one with the other, such that relative electrophoretic mobility of a protein labelled with one dye of the set is the same as the electrophoretic mobility of the protein labelled with a different dye of the set. The matched set comprises at least two different fluorescent dyes of formula: wherein n is 1, 2, or 3; Z1 and Z2 independently represent the carbon atoms necessary to complete a phenyl or naphthyl ring system; one of groups R1 and R2 is a target bonding group; remaining group R1 or R2 is selected from —(CH2)4—W or —(CH2)r—H; group R3 is hydrogen, except when either R1 or R2 is —(CH2)r—H, in which case R3 is W; and W is selected from sulphonic acid and sulphonate.Type: ApplicationFiled: July 8, 2002Publication date: October 20, 2005Inventors: Karen Williams, Timothy Stone, Adrian Simmonds, Alison Sweet, Susan Fowler
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Patent number: 6132698Abstract: Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilizers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xylene Cyanol, Azocarmine B and New Coccine. Preferred compositions contain both stabilizer and dye.Type: GrantFiled: June 10, 1998Date of Patent: October 17, 2000Assignee: Nycomed Amersham PLCInventors: Roger Malcolm Price, Christopher Charles May, Elizabeth Margaret Buckley, Timothy Stone
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Patent number: 5922301Abstract: Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilisers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xylene Cyanol, Azocarmine B and New Coccine. Preferred compositions contain both stabiliser and dye.Type: GrantFiled: June 10, 1997Date of Patent: July 13, 1999Assignee: Nycomed Amersham plcInventors: Roger Malcolm Price, Christopher Charles May, Elizabeth Margaret Buckley, Timothy Stone
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Patent number: 5811072Abstract: Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilisers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xylene Cyanol, Azocarmine B and New Coccine. Preferred compositions contain both stabiliser and dye.Type: GrantFiled: May 6, 1997Date of Patent: September 22, 1998Assignee: Amersham Pharmacia Biotech UK LimitedInventors: Roger Malcolm Price, Christopher Charles May, Elizabeth Margaret Buckley, Timothy Stone
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Patent number: 5686058Abstract: Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilizers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xylene Cyanol, Azocarmine B and New Coccine. Preferred compositions contain both stabilizer and dye.Type: GrantFiled: June 6, 1995Date of Patent: November 11, 1997Assignee: Amersham International plcInventors: Roger Malcolm Price, Christopher Charles May, Elizabeth Margaret Buckley, Timothy Stone
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Patent number: 5667763Abstract: Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilizers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xylene Cyanol, Azocarmine B and New Coccine. Preferred compositions contain both stabilizer and dye.Type: GrantFiled: June 19, 1996Date of Patent: September 16, 1997Assignee: Amersham International plcInventors: Roger Malcolm Price, Christopher Charles May, Elizabeth Margaret Buckley, Timothy Stone
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Patent number: 5512436Abstract: Hybridization buffers, for hybridizing complementary polynucleotides, contain polyvinyl alcohol (MW 1000-20000) and/or polystyrene sulphonic acid (e.g. MW 60000-80000) as a rate enhancer, generally at a concentration of 1-10%. Dextran sulphate, polyethylene glycol and cationic detergents may be additionally present. The method is useful when one of the two complementary polynucleotides is immobilised, or is in in situ hybridizations.Type: GrantFiled: September 2, 1993Date of Patent: April 30, 1996Assignee: Amersham International plcInventor: Timothy Stone
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Patent number: 5494654Abstract: Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilisers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xylene Cyanol, Azocarmine B and New Coccine. Preferred compositions contain both stabiliser and dye.Type: GrantFiled: August 23, 1993Date of Patent: February 27, 1996Assignee: Amersham International plcInventors: Roger M. Price, Christopher C. May, Elizabeth M. Buckley, Timothy Stone