Patents by Inventor Timothy T. Curran

Timothy T. Curran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of derivatives of halo-[2,3-F] quinoline
    Patent number: 7439364
    Abstract: Methods of preparing compounds of Formula I are provided.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: October 21, 2008
    Assignee: Wyeth
    Inventors: Anita W. Chan, Timothy T. Curran, Silvio Iera, Warren Chew, John H. Sellstedt, Galina Vid, Greg Feigelson, Zhixian Ding
  • Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino-[2,3-f] quinoline
    Patent number: 7166723
    Abstract: Methods of preparing compounds of Formula I are provided.
    Type: Grant
    Filed: November 18, 2005
    Date of Patent: January 23, 2007
    Assignee: Wyeth
    Inventors: Anita Wai-Yin Chan, Timothy T. Curran, Silvio Iera, Warren Chew, John Hamilton Sellstedt, Galina Vid, Gregg Feigelson, Zhixian Ding
  • Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline
    Patent number: 7038052
    Abstract: Methods of preparing compounds of Formula I are provided.
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: May 2, 2006
    Assignee: Wyeth
    Inventors: Anita W. Chan, Timothy T. Curran, Silvio Iera, Warren Chew, John H. Sellstedt, Galina Vid, Gregg Feigelson, Zhixian Ding
  • Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline
    Publication number: 20040186123
    Abstract: Methods of preparing compounds of Formula I 1
    Type: Application
    Filed: December 12, 2003
    Publication date: September 23, 2004
    Applicant: Wyeth
    Inventors: Anita W. Chan, Timothy T. Curran, Silvio Iera, Warren Chew, John H. Sellstedt, Galina Vid, Gregg Feigelson, Zhixian Ding
  • Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino- [2,3-f] quinoline
    Patent number: 6693197
    Abstract: Methods of preparing compounds of Formula I are provided.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: February 17, 2004
    Assignee: Wyeth
    Inventors: Anita W. Chan, Timothy T. Curran, Silvio Iera, Warren Chew, John H. Sellstedt, Galina Vid, Gregg Feigelson, Zhixian Ding
  • Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline
    Publication number: 20020187983
    Abstract: Methods of preparing compounds of Formula I 1
    Type: Application
    Filed: May 14, 2002
    Publication date: December 12, 2002
    Applicant: Wyeth
    Inventors: Anita W. Chan, Timothy T. Curran, Silvio Iera, Warren Chew, John H. Sellstedt, Galina Vid, Gregg Feigelson, Zhixian Ding
  • Perfluoroalkyl ketone inhibitors of elastase and processes for making the same
    Patent number: 6008196
    Abstract: This invention relates to compounds which are inhibitors of elastase, particularly human neutrophil elastase, and to novel processes for making the same. As inhibitors of human neutrophil elastase, the compounds are useful in the treatment of a patient afflicted with a neutrophil associated inflammatory disease.
    Type: Grant
    Filed: November 22, 1996
    Date of Patent: December 28, 1999
    Assignee: Hoechst Marion Roussel, Inc.
    Inventors: Timothy T. Curran, Joseph P. Burkhart, Michael R. Angelastro, Norton P. Peet, William A. Metz, Jr.
  • Preparation of cis-4-O-protected-2-cyclopentenol derivatives
    Patent number: 5808112
    Abstract: The present invention relates to a novel process for preparing cis-4-O-protected-substituted-2-cyclopentenol derivatives comprising, a) dissolving a 4-O-protected-2-cyclopentenone in a suitable organic solvent; and b) treating the solution with a suitable Lewis acid and a suitable reducing agent at a temperature of from about -100.degree. C. to about 20.degree. C. The cis-4-O-protected-substituted-2-cyclopentenol derivatives are useful intermediates in the preparation of various cyclopentanyl and cyclopentenyl purine analogs which are useful as immunosuppressants and in the preparation of various prostaglandins.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: September 15, 1998
    Assignee: Hoechst Marion Roussel Inc.
    Inventors: Timothy T. Curran, David A. Hay, Jonathan C. Evans
  • Preparation of cis-4-O-protected-2-cyclopentenol derivatives
    Patent number: 5728899
    Abstract: The present invention relates to a novel process for preparing cis-4-O-protected-substituted-2-cyclopentenol derivatives comprising, a) dissolving a 4-O-protected-2-cyclopentenone in a suitable organic solvent; and b) treating the solution with a suitable Lewis acid and a suitable reducing agent at a temperature of from about -100.degree. C. to about 20.degree. C. The cis-4-O-protected-substituted-2-cyclopentenol derivatives are useful intermediates in the preparation of various cyclopentanyl and cyclopentenyl purine analogs which are useful as immunosuppressants and in the preparation of various prostaglandins.
    Type: Grant
    Filed: February 1, 1996
    Date of Patent: March 17, 1998
    Assignee: Hoechst Marion Roussel Inc.
    Inventors: Timothy T. Curran, David A. Hay, Jonathan C. Evans
  • 4-amino-17.beta.-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17.beta.-(cyclopropylamino)androst-4-en-3-one and related compounds as C.sub.17-20 lyase and 5.alpha.-reductase
    Patent number: 5486511
    Abstract: This invention is directed to 4-amino-17.beta.-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17.beta.-(cyclopropylylamino)androst-4-en-3-one and related compounds, a process for their synthesis, a pharmaceutical composition having C.sub.17-20 lyase and 5.alpha.-reductase inhibitory activity, the use of the present compounds as C.sub.17-20 lyase and 5.alpha.-reductase inhibitors and also to a method for using such compounds in the treatment of androgen and/or estrogen dependent disorders, including bengin prostatic hyperplasia, breast cancer and prostatic cancer. The 4-amino compounds are prepared by the reaction of the appropriate 4,5-epoxide with sodium azide in an inert solvent in the presence of a catalytic amount of strong acid under appropriate reaction conditions. Alternatively, the 4-amino compounds are prepared by first nitration and then reduction of the appropriate steroid under appropriate reaction conditions.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: January 23, 1996
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Philip M. Weintraub, Cynthia A. Gates, Michael R. Angelastro, Timothy T. Curran, J. O'Neal Johnston