Abstract: A purification module is provided comprising a plurality of purification cartridges, a support for the cartridges, a manifold and a bowl. In one embodiment the support for the cartridges has two pitched partial screw threads on opposing surfaces which mate with pitched screw flights on the manifold when the partial screw threads are rotated into the screw flights. The support includes fluid passageways for directing filtered fluid from the filtration cartridges, through the support and into the manifold. In another embodiment, a purification module is provided comprising a purification cartridge, a manifold and a bowl. The purification cartridge has two pitched partial screw threads on opposing surfaces of the cartridge outlet which mate with screw flights on the manifold when the partial screw threads are rotated into the mating screw flights.

Abstract: Systems and methods of route-specific searching are provided. Information about a first location and second location may be processed. The information about the second location may be from a user and may indicate a destination. A first route from the first location to the second location may be identified. A search query may be processed. Search results may be identified, and, a third location corresponding to the search result may be identified. A route from the first location to the third location to the second location may be determined. A deviation of the route with respect to the first route may be determined. A search result may be selected based on the deviation. A map may depict an area including the first location, the second location, and the third location. The route from the first location to the third location to the second location may be indicated.

Abstract: A method of presenting fuel prices and corresponding fuel providers in a geographical area of interest to a user of a mobile computing device is provided. A mobile application is provided. A first set of fuel pricing information stored in a repository, information about a first location, and a subset of fuel pricing information are processed. The subset of fuel pricing information corresponds to a second set of fuel prices offered within an area proximal to the first location. The subset of fuel pricing information is categorized according to price, identifying each of the second set as corresponding to one of two or more price categories. Indication of fuel prices corresponding to the first price category is caused. Indication of locations corresponding to the first price category is caused.

Abstract: A purification module is provided comprising a plurality of purification cartridges, a support for the cartridges, a manifold and a bowl. In one embodiment the support for the cartridges has two pitched partial screw threads on opposing surfaces which mate with pitched screw flights on the manifold when the partial screw threads are rotated into the screw flights. The support includes fluid passageways for directing filtered fluid from the filtration cartridges, through the support and into the manifold. In another embodiment, a purification module is provided comprising a purification cartridge, a manifold and a bowl. The purification cartridge has two pitched partial screw threads on opposing surfaces of the cartridge outlet which mate with screw flights on the manifold when the partial screw threads are rotated into the mating screw flights.

Abstract: A clamshell fabrication process wherein an ultrafiltration (UF) vessel (or a strip or array of filter vessels) is formed using half cells joined along a central plane to form each vessel. A filter membrane covers a port of the cell, and an outer body is overmolded to form the completed vessel. Two filter membranes are crushed together skin to skin. When applied to strips of half cells, a multi-well strip or array is formed, with sample-holding reservoirs formed by the space created between two strips of half-cells for each row of filter cells. The membrane thus covers the entire wetted interior of each cell, and may extend from near the opening at the top of an open cell to a conical bottom of the cell. A number of strip assemblies can be formed together to create larger arrays of filter cells. The overmolding process creates a crush seal with edges of the filter membrane.

Abstract: An ultrafiltration device has a ported reservoir body, and a filter membrane sealed to the body along a closed contour surrounding the port(s) to provide a large area filtered outflow path. A frusto-conical end provides hydrostatic deadstopping with little or no wicking, greatly enhancing recovery time and efficiency. Methods of using the device rapidly isolate a predetermined amount of a desired retentate in the distal portion of the tube, and are also useful for quantitative transfer of smaller molecules and for multi-step processing of sample arrays Linear array strips of such chambers may be formed by bonding together mating halves with filter areas over the chamber ports. The vessel may include a rib to guide and orient filter during assembly, and/or a ledge or recess to engage and align the filter, assuring that the filter is precisely positioned and does not wander during manufacture and bonding.

Abstract: An ultrafiltration device has a filter membrane sealed inside a reservoir body, such as a tube. The tube has one or more ports and a closed portion distal to the port(s), and the filter membrane is sealed to the body along a closed contour widely surrounding the port(s) to provide a large area filtered outflow path. The method is effective to rapidly isolate a predetermined amount of a desired retentate in the distal portion of the tube. The method and device are also useful for quantitative transfer of smaller molecules and for multi-step processing of sample arrays. A frusto-conical peripheral filter provides high ratio of effective filter area, and may be configured for hydrostatic deadstopping and little or no wicking, greatly enhancing recovery time and efficiency. Linear array strips of such chambers may be formed by bonding together mating halves with filter areas over the chamber ports.

Abstract: An ultrafiltration device has a filter membrane sealed inside a reservoir body that has one or more ports and a closed portion distal to the port(s), and the filter membrane is sealed to the body along a closed contour widely surrounding the port(s) to provide a large area filtered outflow path. The method is effective to rapidly isolate a predetermined amount of a desired retentate in the distal portion and is also useful for quantitative transfer of smaller molecules and for multi-step processing of sample arrays. A frusto-conical peripheral filter provides high ratio of effective filter area, and may be configured for hydrostatic deadstopping and little or no wicking, greatly enhancing recovery time and efficiency. Novel constructions and methods of manufacture enhance filtration or separation vessels of various sizes.