Abstract: The current invention includes systems, methods and compositions for the generation of sRNA molecules using select RNase III mutants. In one preferred embodiment, invention includes systems, methods and compositions for the generation of sRNA molecules using RNase III mutants to control a host pathogen through the production and diffusion of sRNA molecules that may initiate an RNAi pathway response directed to a host pathogen. Additional embodiments of the current invention include systems, methods and compositions for the DICER-independent generation of sRNA molecules using select RNase III mutants.

Abstract: The present invention relates generally to the identification novel UDP-glucosyltransferases enzymes having specific activity towards cannabinoid compounds. The present invention further relates generally to the use of novel UGT enzymes having specific activity towards cannabinoid compounds to generate water-soluble cannabinoid glycoside compounds.

Abstract: The present invention relates generally to the use of novel UDP-glucosyltransferases enzymes having specific activity towards cannabinoid compounds. The present invention further relates generally to the use of novel UGT enzymes having specific activity towards cannabinoid compounds to generate water-soluble cannabinoid glycoside compounds.

Abstract: The inventive technology includes novel systems, methods, and compositions for the generation of water-soluble short-chain fatty acid phenolic compounds, preferably cannabinoids, terpenes, and other volatile compounds produced in Cannabis. In particular, the inventive technology includes novel systems, methods, and compositions to solubilize short-chain fatty acid phenolic coin-pounds, such as cannabinoids, via binding to a water soluble and readily digested carrier protein such as: lipocalins, lipocalin-like, odorant-binding proteins, and odorant-binding-like proteins.

Abstract: The inventive technology includes novel systems, methods, and compositions for the generation of water-soluble short-chain fatty acid phenolic compounds, preferably cannabinoids, terpenes, and other volatile compounds produced in Cannabis and other cannabinoid producing plants. In particular, the inventive technology includes novel systems and methods to solubilize short-chain fatty acid phenolic compounds, such as cannabinoids, via binding to a water soluble and readily digested carrier protein.

Abstract: To reduce cost and improve accuracy, the inventors devised systems, methods, and software to aid classification of text, such as headnotes and other documents, to target classes in a target classification system. For example, one system computes composite scores based on: similarity of input text to text assigned to each of the target classes; similarity of non-target classes assigned to the input text and target classes; probability of a target class given a set of one or more non-target classes assigned to the input text; and/or probability of the input text given text assigned to the target classes. The exemplary system then evaluates the composite scores using class-specific decision criteria, such as thresholds, ultimately assigning or recommending assignment of the input text to one or more of the target classes. The exemplary system is particularly suitable for classification systems having thousands of classes.

Abstract: To reduce cost and improve accuracy, the inventors devised systems, methods, and software to aid classification of text, such as headnotes and other documents, to target classes in a target classification system. For example, one system computes composite scores based on: similarity of input text to text assigned to each of the target classes; similarity of non-target classes assigned to the input text and target classes; probability of a target class given a set of one or more non-target classes assigned to the input text; and/or probability of the input text given text assigned to the target classes. The exemplary system then evaluates the composite scores using class-specific decision criteria, such as thresholds, ultimately assigning or recommending assignment of the input text to one or more of the target classes. The exemplary system is particularly suitable for classification systems having thousands of classes.