Patents by Inventor Timothy W. Behrens

Timothy W. Behrens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systemic lupus erythematosus
    Patent number: 7571055
    Abstract: This document relates to methods and materials involved in diagnosing SLE. For example, this document relates to methods and materials involved in diagnosing SLE, diagnosing severe SLE, and assessing a mammal's susceptibility to develop severe SLE. For example, this document provides nucleic acid arrays that can be used to diagnose SLE in a mammal. Such arrays can allow clinicians to diagnose SLE based on a simultaneous determination of the expression levels of many genes that are differentially expressed in SLE patients as compared to healthy controls. In addition, methods and materials for assessing SLE activity, determining the likelihood of experiencing active SLE, and detecting SLE treatment effectiveness are provided herein.
    Type: Grant
    Filed: October 13, 2005
    Date of Patent: August 4, 2009
    Assignees: Regents of the University of Minnesota, The Feinstein Institute for Medical Research
    Inventors: Timothy W. Behrens, Emily C. Gillespie, Peter K. Gregersen
  • BIOLOGICAL MARKERS PREDICTIVE OF RHEUMATOID ARTHRITIS RESPONSE TO B-CELL ANTAGONISTS
    Publication number: 20090004189
    Abstract: Methods and assays examining expression of one or more biomarkers in a sample are provided for predicting or indicating the effectiveness of treatment of a rheumatoid arthritis patient with a B-cell antagonist. Methods are provided for identifying patients whose rheumatoid arthritis is likely to be responsive to B-cell-antagonist, anti-rheumatoid arthritis therapy. Methods for treating such patients with B-cell antagonists that incorporate the above methodology are also provided. Further provided are kits and articles of manufacture useful for such methods.
    Type: Application
    Filed: June 13, 2008
    Publication date: January 1, 2009
    Applicant: Genentech, Inc.
    Inventors: TIMOTHY W. BEHRENS, Michael J. Townsend
  • METHODS FOR DIAGNOSING SYSTEMIC LUPUS ERYTHEMATOSUS
    Publication number: 20080108058
    Abstract: The invention relates to methods and materials involved in diagnosing SLE. More particularly, the invention relates to methods and materials involved in diagnosing SLE, diagnosing severe SLE, and assessing a mammal's susceptibility to develop severe SLE. For example, the invention provides nucleic acid arrays that can be used to diagnose SLE in a mammal. Such arrays can allow clinicians to diagnose SLE based on a simultaneous determination of the expression levels of many genes that are differentially expressed in SLE patients as compared to healthy controls.
    Type: Application
    Filed: October 3, 2006
    Publication date: May 8, 2008
    Applicants: REGENTS OF THE UNIVERSITY OF MINNESOTA, Feinstein Institute for Medical Research
    Inventors: Timothy W. Behrens, Emily C. Baechler, Peter K. Gregersen
  • Methods for diagnosing severe systemic lupus erythematosus
    Patent number: 7118865
    Abstract: The invention relates to methods and materials involved in diagnosing SLE. More particularly, the invention relates to methods and materials involved in diagnosing SLE, diagnosing severe SLE, and assessing a mammal's susceptibility to develop severe SLE. For example, the invention provides nucleic acid arrays that can be used to diagnose SLE in a mammal. Such arrays can allow clinicians to diagnose SLE based on a simultaneous determination of the expression levels of many genes that are differentially expressed in SLE patients as compared to healthy controls.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: October 10, 2006
    Assignees: Regents of the University of Minnesota, The Feinstein Institute for Medical Research
    Inventors: Timothy W. Behrens, Emily C. Baechler, Peter K. Gregersen
  • Systemic lupus erythematosus
    Publication number: 20040033498
    Abstract: The invention relates to methods and materials involved in diagnosing SLE. More particularly, the invention relates to methods and materials involved in diagnosing SLE, diagnosing severe SLE, and assessing a mammal's susceptibility to develop severe SLE. For example, the invention provides nucleic acid arrays that can be used to diagnose SLE in a mammal. Such arrays can allow clinicians to diagnose SLE based on a simultaneous determination of the expression levels of many genes that are differentially expressed in SLE patients as compared to healthy controls.
    Type: Application
    Filed: August 16, 2002
    Publication date: February 19, 2004
    Inventors: Timothy W. Behrens, Emily C. Baechler, Peter K. Gregersen