Patents by Inventor Timothy W. Graul

Timothy W. Graul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8685219
    Abstract: An apparatus for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica and the polyelectrolyte multilayer positioned within the passage. The polyelectrolyte multilayer comprises layers with alternating charge. The apparatus includes a power supply having a positive electrode and a negative electrode for generating an electric field therebetween and a sensor positioned adjacent the passage for sensing macromolecules.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: April 1, 2014
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Joseph B. Schlenoff, Timothy W. Graul
  • Patent number: 7594986
    Abstract: An apparatus and method for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica. The polyelectrolyte multilayer is positioned within the passage adjacent the walls, and comprises an organic polyelectrolyte. The passage may further comprise nonporous silica particles coated with a multilayer including a plurality of polyelectrolyte layers. An apparatus includes a power supply having a positive electrode and a negative electrode for generating an electric field therebetween. The apparatus includes a capillary having a passage formed by passage walls and comprising therein a polyelectrolyte multilayer positioned substantially within the passage.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: September 29, 2009
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Joseph B. Schlenoff, Timothy W. Graul
  • Patent number: 7285421
    Abstract: An apparatus and method for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica. The polyelectrolyte multilayer is positioned within the passage adjacent the walls, and comprises an organic polyelectrolyte. The passage may further comprise nonporous silica particles coated with a multilayer including a plurality of polyelectrolyte layers. An apparatus includes a power supply having a positive electrode and a negative electrode for generating an electric field therebetween. The apparatus includes a capillary having a passage formed by passage walls and comprising therein a polyelectrolyte multilayer positioned substantially within the passage.
    Type: Grant
    Filed: September 2, 2004
    Date of Patent: October 23, 2007
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Joseph B. Schlenoff, Timothy W. Graul
  • Patent number: 6841054
    Abstract: An apparatus and method for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica. The polyelectrolyte multilayer is positioned within the passage adjacent the walls, and comprises an organic polyelectrolyte. The passage may further comprise nonporous silica particles coated with a multilayer including a plurality of polyelectrolyte layers. An apparatus includes a power supply having a positive electrode and a negative electrode for generating an electric field therebetween. The apparatus includes a capillary having a passage formed by passage walls and comprising therein a polyelectrolyte multilayer positioned substantially within the passage.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: January 11, 2005
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Joseph B. Schlenoff, Timothy W. Graul
  • Publication number: 20020130045
    Abstract: An apparatus and method for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica. The polyelectrolyte multilayer is positioned within the passage adjacent the walls, and comprises an organic polyelectrolyte. The passage may further comprise nonporous silica particles coated with a multilayer including a plurality of polyelectrolyte layers. An apparatus includes a power supply having a positive electrode and a negative electrode for generating an electric field therebetween. The apparatus includes a capillary having a passage formed by passage walls and comprising therein a polyelectrolyte multilayer positioned substantially within the passage.
    Type: Application
    Filed: May 14, 2002
    Publication date: September 19, 2002
    Inventors: Joseph B. Schlenoff, Timothy W. Graul
  • Patent number: 6402918
    Abstract: An apparatus and method for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica. The polyelectrolyte multilayer is positioned within the passage adjacent the walls, and comprises an organic polyelectrolyte. The passage may further comprise nonporous silica particles coated with a multilayer including a plurality of polyelectrolyte layers. An apparatus includes a power supply having a positive electrode and a negative electrode for generating an electric field therebetween. The apparatus includes a capillary having a passage formed by passage walls and comprising therein a polyelectrolyte multilayer positioned substantially within the passage.
    Type: Grant
    Filed: November 16, 1999
    Date of Patent: June 11, 2002
    Inventors: Joseph B. Schlenoff, Timothy W. Graul