Patents by Inventor Tina Holm Johansen

Tina Holm Johansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Pyrimidine-2,4-Diamine Derivatives and their Use as Modulators of Small-Conductance Calcium-Activated Potassium Channels
    Publication number: 20090124645
    Abstract: This invention relates to novel pyrimidine-2,4-diamine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: October 13, 2006
    Publication date: May 14, 2009
    Applicant: NeuroSearch A/S
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen
  • NOVEL GUANIDINE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20090099208
    Abstract: This invention relates to novel guanidine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: March 22, 2007
    Publication date: April 16, 2009
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen
  • 2-(Phenylamino) Benzimidazole Derivatives and Their Use as Modulators of Small- Conductance Calcuim-Activated Potassium Channels
    Publication number: 20090076106
    Abstract: This invention relates to novel 2-(phenylamino)benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 21, 2006
    Publication date: March 19, 2009
    Applicant: NEUROSEARCH A/S
    Inventors: Ulrik Svane Sorensen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • Novel Quinazoline-2,4-Diamine Derivatives and Their Use as Modulators of Small-Conductance Calcium-Activated Potassium Channels
    Publication number: 20090048278
    Abstract: This invention relates to novel quinazoline-2,4-diamine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: December 6, 2006
    Publication date: February 19, 2009
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen
  • Novel 2-Amino Benzimidazole Derivatives and Their Use As Modulators Of Small-Conductance Calcium-Activated Potassium Channels
    Publication number: 20080200529
    Abstract: This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: January 10, 2006
    Publication date: August 21, 2008
    Applicant: NEURO SEARCH A/S
    Inventors: Ulrik Svane Sorensen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • Compounds and their use as positive AMPA receptor modulators
    Patent number: 7235548
    Abstract: The invention provides novel compounds represented by the general formula compound represented by the formula: wherein the bond represented by the broken line may be a single, a double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R2; X represents SO2 or C?O or CH2; Y represents —CH(R4)—, —N(R4)— or —N(R4)—CH2—, O; and the meaning of R2, R3, R4, R5, R6, R7, and R8 are as defined in the application The compounds are useful as positive modulators of the AMPA-receptor.
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: June 26, 2007
    Assignee: NeuroSearch A/S
    Inventors: Alex Haaht Gouliaev, Mogens Larsen, Thomas Varming, Claus Mathiesen, Tina Holm Johansen, Jorgen Scheel-Kruger, Gunnar M. Olsen, Elsesbet Ostergaard Nielsen
  • Benzothiazine derivatives, their preparation and use
    Patent number: 7199118
    Abstract: This invention relates to novel benzothiazine derivatives of Formula I useful as modulators of the AMPA sensitive glutamate receptors, pharmaceutical compositions comprising such compounds and their use in therapy.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: April 3, 2007
    Assignee: NeuroSearch A/S
    Inventors: Alex Haahr Gouliaev, Morgens Larsen, Thomas Varming, Claus Mathiesen, Tina Holm Johansen, Karin Sandager Nielsen, Barbara Hartz, Jorgen Scheel-Kruger
  • Compounds and their use as positive AMPA receptor modulators
    Patent number: 6943159
    Abstract: The invention provides novel compounds represented by general formula (I) wherein the bond represented by the broken line may be a single, double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R2; X represents SO2 or C?O of CH2; Y represents —CH(R4)—, —N(R4)—CH2—, O; and the meaning of R2, R3, R4, R5, R6, R7, and R8 are as defined in the application. The compounds are useful as positive modulators of the AMPA-receptor.
    Type: Grant
    Filed: August 18, 2000
    Date of Patent: September 13, 2005
    Assignee: Neurosearch A/S
    Inventors: Alex Haahr Gouliaev, Mogens Larsen, Thomas Varming, Claus Mathiesen, Tina Holm Johansen, Jørgen Scheel-Krüger, Gunnar M. Olsen, Elsebet Østergaard Nielsen
  • Novel benzothiazine derivatives, their preparation and use
    Publication number: 20040242571
    Abstract: This invention relates to novel benzothiazine derivatives of Formula I useful as modulators of the AMPA sensitive glutamate receptors, pharmaceutical compositions comprising such compounds and their use in therapy.
    Type: Application
    Filed: March 15, 2004
    Publication date: December 2, 2004
    Inventors: Alex Haahr Gouliaev, Morgens Larsen, Thomas Varming, Claus Mathiesen, Tina Holm Johansen, Karin Sandager Nielsen, Barbara Hartz, Jorgen Scheel-Kruger
  • Novel compounds and their use as positive AMPA receptor modulators
    Publication number: 20040043987
    Abstract: The invention provides novel compounds represented by the general formula 5 compound represented by the formula: 1
    Type: Application
    Filed: August 18, 2003
    Publication date: March 4, 2004
    Applicant: Neurosearch A/S.
    Inventors: Alex Haaht Gouliaev, Mogens Larsen, Thomas Varming, Claus Mathiesen, Tina Holm Johansen, Jorgen Scheel-Kruger, Gunnar M. Olsen, Elsesbet Ostergaard Nielsen