Patents by Inventor Tina Morwick

Tina Morwick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
    Patent number: 7405225
    Abstract: Disclosed are compounds of formula (I): wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the I?B kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: July 29, 2008
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Zhidong Chen, Jonathan Emeigh, Roman Wolfgang Fleck, Ming-Hong Hao, Eugene Hickey, Weimin Liu, Daniel Richard Marshall, Tina Morwick, Peter Nemoto, Ronald John Sorcek, Sanxing Sun, Jiang-Ping Wu
  • Substituted Tricyclic Heterocycles and their Uses
    Publication number: 20080008720
    Abstract: Disclosed are substituted tricyclic heterocycle compounds of the formulas (I), (II) and (III) shown below, wherein R1, R2, R3 and R4 are described herein, which are active as anti-inflammatory agents. Also disclosed are methods of using and making such compounds.
    Type: Application
    Filed: August 9, 2007
    Publication date: January 10, 2008
    Inventors: Charles Cywin, Roman Fleck, Eugene Hickey, Weimin Liu, Tina Morwick, John Proudfoot, Denice Spero
  • Anti-Cytokine Heterocyclic Compounds
    Publication number: 20060276496
    Abstract: Heterocyclic compounds and analogues thereof and their use as inhibitors of Mitogen-Activated Protein Kinase-Activated Protein kinase-2 (MAPKAP-k2), and also to a method for preventing or treating a disease or disorder that can be treated or prevented by modulating the activity of MAPKAP-K2 in a subject and to pharmaceutical compositions and kits that include these MAPKAP-K2 inhibitors.
    Type: Application
    Filed: March 17, 2006
    Publication date: December 7, 2006
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Daniel Goldberg, Asitha Abeywardane, Craig Miller, Tina Morwick, Matthew Netherton, Roger Snow, Ji Wang, Jiang-Ping Wu, Zhaoming Xiong
  • Anti-Cytokine Heterocyclic Compounds
    Publication number: 20060276453
    Abstract: Heterocyclic compounds and analogues thereof and their use as inhibitors of Mitogen-Activated Protein Kinase-Activated Protein kinase-2 (MAPKAP-k2), and also to a method for preventing or treating a disease or disorder that can be treated or prevented by modulating the activity of MAPKAP-K2 in a subject and to pharmaceutical compositions and kits that include these MAPKAP-K2 inhibitors.
    Type: Application
    Filed: March 17, 2006
    Publication date: December 7, 2006
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Daniel Goldberg, Asitha Abeywardane, Craig Miller, Tina Morwick, Matthew Netherton, Roger Snow, Ji Wang, Jiang-Ping Wu, Zhaoming Xiong
  • Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
    Publication number: 20050288285
    Abstract: Disclosed are compounds of formula (I): wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the I?B kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
    Type: Application
    Filed: August 18, 2005
    Publication date: December 29, 2005
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles Cywin, Zhidong Chen, Roman Fleck, Ming-Hong Hao, Eugene Hickey, Weimin Liu, Daniel Marshall, Peter Nemoto, Ronald Sorcek, Sanxing Sun, Jiang-Ping Wu, Tina Morwick, Jonathan Emeigh
  • Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
    Patent number: 6974870
    Abstract: Disclosed are compounds of formula (I): wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the I?B kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
    Type: Grant
    Filed: December 6, 2003
    Date of Patent: December 13, 2005
    Assignee: Boehringer Ingelheim Phamaceuticals, Inc.
    Inventors: Charles L. Cywin, Can Mao, Jonathan Emeigh, Roman Wolfgang Fleck, Ming-Hong Hao, Eugene Hickey, Weimin Liu, Daniel Richard Marshall, Tina Morwick, Peter Nemoto, Ronald John Sorcek, Sanxing Sun, Jiang-Ping Wu, Erick Young, Darren DiSalvo, John Ginn, Pier Cirillo
  • Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
    Patent number: 6964956
    Abstract: Disclosed are compounds of formula (I): wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the I?B kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
    Type: Grant
    Filed: June 3, 2003
    Date of Patent: November 15, 2005
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Zhidong Chen, Roman Wolfgang Fleck, Ming-Hong Hao, Eugene Hickey, Weimin Liu, Daniel Richard Marshall, Peter Nemoto, Ronald John Sorcek, Sanxing Sun, Jiang-Ping Wu, Tina Morwick, Jonathan Emeigh
  • Substituted tricyclic heterocycles and their uses
    Publication number: 20050101601
    Abstract: Disclosed are substituted tricyclic heterocycle compounds of the formulas (I), (II) and (III) shown below, wherein R1, R2, R3 and R4 are described herein, which are active as anti-inflammatory agents. Also disclosed are methods of using and making such compounds.
    Type: Application
    Filed: October 7, 2004
    Publication date: May 12, 2005
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles Cywin, Roman Fleck, Eugene Hickey, Weimin Liu, Tina Morwick, John Proudfoot, Denice Spero
  • Substitute benzothiophene compounds
    Publication number: 20050038104
    Abstract: Disclosed are compounds of the formula I shown below, wherein R1, R2, R3 and R4 are described herein, which are active as anti-inflammatory agents. Also disclosed are methods of using and making such compounds.
    Type: Application
    Filed: July 29, 2004
    Publication date: February 17, 2005
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Zhidong Chen, John Ginn, Eugene Hickey, Weimin Liu, Can Mao, Tina Morwick, Peter Nemoto, Denice Spero, Sanxing Sun
  • Compounds useful as reversible inhibitors of cysteine proteases
    Publication number: 20050032772
    Abstract: Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formulas (I), (II), (Ia) and (Ib) further defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes for making such novel compounds.
    Type: Application
    Filed: September 9, 2004
    Publication date: February 10, 2005
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Michel Emmanuel, Leah Frye, Eugene Hickey, Weimin Liu, Tina Morwick, Denice Spero, Sanxing Sun, David Thomson, Yancey Ward, Erick Young
  • Compounds useful as reversible inhibitors of cysteine proteases
    Publication number: 20050032792
    Abstract: Disclosed are cathepsin S ,K, F, L and B reversible inhibitory compounds of the formulas (I), (II), (Ia) and (Ib) further defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes for making such novel compounds.
    Type: Application
    Filed: September 9, 2004
    Publication date: February 10, 2005
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Michel Emmanuel, Leah Frye, Eugene Hickey, Weimin Liu, Tina Morwick, Denice Spero, David Thomson, Yancey Ward, Erick Young
  • Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
    Publication number: 20040180922
    Abstract: Disclosed are compounds of formula (I): 1
    Type: Application
    Filed: December 6, 2003
    Publication date: September 16, 2004
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Can Mao, Jonathan Emeigh, Roman Wolfgang Fleck, Ming-Hong Hao, Eugene Hickey, Weimin Liu, Daniel Richard Marshall, Tina Morwick, Peter Nemoto, Ronald John Sorcek, Sanxing Sun, Jiang-Ping Wu, Erick Young, Darren DiSalvo, John Ginn, Pier Cirillo
  • Heterocyclic compounds useful as inhibitors of tyrosine kinases
    Patent number: 6770639
    Abstract: Disclosed are novel compounds of formula (I): wherein Ar1, Ra, R4, R5, X and Y are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases associated with such kinases, for example, diseases resulting from inappropriate cell proliferation, which include autoimmune diseases, chronic inflammatory diseases, allergic diseases, transplant rejection and cancer, as well as conditions resulting from cerebral ischemia, such as stroke. Also disclosed are processes for preparing these compounds, novel intermediates useful in these processes and compositions comprising compounds of the formula (I).
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: August 3, 2004
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Roger John Snow, Mario Cardozo, Daniel Goldberg, Abdelhakim Hammach, Tina Morwick, Neil Moss, Usha R. Patel, Anthony S. Prokopowicz, III, Hidenori Takahashi, Matt Aaron Tschantz, Xiao-Jun Wang
  • Compounds useful as reversible inhibitors of cathespin S
    Patent number: 6730671
    Abstract: Disclosed are cathepsin S reversible inhibitory compounds of the formulas (I),(Ia) and (II),(IIa) as defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes, for making such novel compounds.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: May 4, 2004
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Michel J. Emmanuel, Tina Morwick, Denice M. Spero, David S. Thomson, Yancey D. Ward
  • Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
    Publication number: 20040053957
    Abstract: Disclosed are compounds of formula (I): 1
    Type: Application
    Filed: June 3, 2003
    Publication date: March 18, 2004
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Zhidong Chen, Roman Wolfgang Fleck, Ming-Hong Hao, Eugene Hickey, Weimin Liu, Daniel Richard Marshall, Peter Nemoto, Ronald John Sorcek, Sanxing Sun, Jiang-Ping Wu, Tina Morwick, Jonathan Emeigh
  • Compounds useful as reversible inhibitors of cathepsin S
    Publication number: 20030158406
    Abstract: Disclosed are cathepsin S reversible inhibitory compounds of the formulas (I), (Ia) and (II), (IIa) as defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes for making such novel compounds.
    Type: Application
    Filed: February 13, 2003
    Publication date: August 21, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Michel J. Emmanuel, Tina Morwick, Denice M. Spero, David S. Thomson, Yancey D. Ward
  • Compounds useful as reversible inhibitors of cathepsin S
    Patent number: 6608057
    Abstract: Disclosed are cathepsin S reversible inhibitory compounds of the formulas (I),(Ia) and (II),(IIa) as defined herein. The compounds are useful for treating autoimmune diseases.
    Type: Grant
    Filed: October 24, 2001
    Date of Patent: August 19, 2003
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles L. Cywin, Michel J. Emmanuel, Tina Morwick, Denice M. Spero, David S. Thomson, Yancey D. Ward
  • Heterocyclic compounds useful as inhibitors of tyrosine kinases
    Patent number: 6506769
    Abstract: Disclosed are novel compounds of formula (I): wherein Ar1, Ra, R4, R5, X and Y are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases associated with such kinases, for example, diseases resulting from inappropriate cell proliferation, which include autoimmune diseases, chronic inflammatory diseases, allergic diseases, transplant rejection and cancer, as well as conditions resulting from cerebral ischemia, such as stroke. Also disclosed are processes for preparing these compounds, novel intermediates useful in these processes and compositions comprising compounds of the formula (I).
    Type: Grant
    Filed: August 2, 2001
    Date of Patent: January 14, 2003
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Roger John Snow, Mario Cardozo, Daniel Goldberg, Abdelhakim Hammach, Tina Morwick, Neil Moss, Usha R. Patel, Anthony S. Prokopowicz, III, Hidenori Takahashi, Matt Aaron Tschantz, Xiao-Jun Wang
  • Compounds useful as reversible inhibitors of cathepsin S
    Publication number: 20020091259
    Abstract: Disclosed are cathepsin S reversible inhibitory compounds of the formulas (I),(Ia) and (II),(IIa) as defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes for making such novel compounds.
    Type: Application
    Filed: February 24, 2002
    Publication date: July 11, 2002
    Inventors: Charles L. Cywin, Michel J. Emmanuel, Tina Morwick, Denice M. Spero, David S. Thomson, Yancey D. Ward
  • Heterocyclic compounds useful as inhibitors of tyrosine kinases
    Publication number: 20020016460
    Abstract: Disclosed are novel compounds of formula (I): 1
    Type: Application
    Filed: August 2, 2001
    Publication date: February 7, 2002
    Inventors: Roger John Snow, Mario Cardozo, Daniel Goldberg, Abdelhakim Hammach, Tina Morwick, Neil Moss, Usha R. Patel, Anthony S. Prokopowicz, Hidenori Takahashi, Matt Aaron Tschantz, Xiao-Jun Wang