Patents by Inventor Tina R. Ivanov

Tina R. Ivanov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA encoding a human imidazoline receptor and ligand binding assay employing same
    Patent number: 7384752
    Abstract: A cDNA encoding a human imidazoline receptor is described. The amino acid sequence of the entire imidazoline receptor protein is identified, as well as a C-terminal fragment believed to contain the imidazoline binding site of the receptor. The protein is highly unique in its sequence and may represent the first in a novel family of receptor proteins. Methods of cloning the cDNA and expressing the imidazoline receptor in a host cell are described. Also, a screening method for identifying drugs that interact with the imidazoline receptor is described.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: June 10, 2008
    Assignee: University of Mississippi Medical Center
    Inventors: John E. Piletz, Tina R. Ivanov
  • Imidazoline receptive polypeptides
    Patent number: 6881826
    Abstract: A genomic DNA encoding a human imidazoline receptor is described. cDNAs encoding the receptor and fragments thereof are also provided. An amino acid sequence predicted to be 120,000 MW for nearly the entire protein is identified, as well as a middle fragment believed to contain the imidazoline binding site of the receptor. The protein is highly unique in its sequence and may represent the first in a novel family of receptor proteins. Methods of cloning the cDNA and expressing the imidazoline receptor in a host cell are described. Methods of preparing antibodies against the transfected protein are also described. Also, a screening method for identifying additional subtypes of this receptor are identified. Also, screening methods for identifying drugs that interact with the imidazoline receptor are described.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: April 19, 2005
    Assignee: The University of Mississippi Medical Center
    Inventors: John E. Piletz, Tina R. Ivanov
  • DNA sequence encoding a human imidazoline receptor and method for cloning the same
    Publication number: 20030224429
    Abstract: A cDNA encoding a human imidazoline receptor is described. The amino acid sequence of the entire imidazoline receptor protein is identified, as well as a C-terminal fragment believed to contain the imidazoline binding site of the receptor. The protein is highly unique in its sequence and may represent the first in a novel family of receptor proteins. Methods of cloning the cDNA and expressing the imidazoline receptor in a host cell are described. Also, a screening method for identifying drugs that interact with the imidazoline receptor is described.
    Type: Application
    Filed: April 24, 2003
    Publication date: December 4, 2003
    Applicant: The University of Mississippi Medical Center
    Inventors: John E. Piletz, Tina R. Ivanov
  • DNA molecules encoding imidazoline receptive polypeptides and polypeptides encoded thereby
    Publication number: 20030180885
    Abstract: A genomic DNA encoding a human imidazoline receptor is described. cDNAs encoding the receptor and fragments thereof are also provided. An amino acid sequence predicted to be 120,000 MW for nearly the entire protein is identified, as well as a middle fragment believed to contain the imidazoline binding site of the receptor. The protein is highly unique in its sequence and may represent the first in a novel family of receptor proteins. Methods of cloning the cDNA and expressing the imidazoline receptor in a host cell are described. Methods of preparing antibodies against the transfected protein are also described. Also, a screening method for identifying additional subtypes of this receptor are identified. Also, screening methods for identifying drugs that interact with the imidazoline receptor are described.
    Type: Application
    Filed: April 23, 2003
    Publication date: September 25, 2003
    Applicant: The University of Mississippi Medical Center
    Inventors: John E. Piletz, Tina R. Ivanov
  • DNA sequence encoding a human imidazoline receptor and method for cloning the same
    Patent number: 6576742
    Abstract: A cDNA encoding a human imidazoline receptor is described. The amino acid sequence of the entire imidazoline receptor protein is identified, as well as a C-terminal fragment believed to contain the imidazoline binding site of the receptor. The protein is highly unique in its sequence and may represent the first in a novel family of receptor proteins. Methods of cloning the cDNA and expressing the imidazoline receptor in a host cell are described. Also, a screening method for identifying drugs that interact with the imidazoline receptor is described.
    Type: Grant
    Filed: September 3, 1999
    Date of Patent: June 10, 2003
    Assignee: The University of Mississippi Medical Center
    Inventors: John E. Piletz, Tina R. Ivanov
  • DNA molecules encoding imidazoline receptive polypeptides and polypeptides encoded thereby
    Patent number: 6033871
    Abstract: A genomic DNA encoding a human imidazoline receptor is described. cDNAs encoding the receptor and fragments thereof are also provided. An amino acid sequence predicted to be 120,000 MW for nearly the entire protein is identified, as well as a middle fragment believed to contain the imidazoline binding site of the receptor. The protein is highly unique in its sequence and may represent the first in a novel family of receptor proteins. Methods of cloning the cDNA and expressing the imidazoline receptor in a host cell are described. Methods of preparing antibodies against the transfected protein are also described. Also, a screening method for identifying additional subtypes of this receptor are identified. Also, screening methods for identifying drugs that interact with the imidazoline receptor are described.
    Type: Grant
    Filed: September 3, 1997
    Date of Patent: March 7, 2000
    Assignee: The University of Mississppi Medical Center
    Inventors: John E. Piletz, Tina R. Ivanov
  • DNA sequence encoding a human imidazoline receptor and method for cloning the same
    Patent number: 6015690
    Abstract: A cDNA encoding a human imidazoline receptor is described. The amino acid sequence of the entire imidazoline receptor protein is identified, as well as a C-terminal fragment believed to contain the imidazoline binding site of the receptor. The protein is highly unique in its sequence and may represent the first in a novel family of receptor proteins. Methods of cloning the cDNA and pressing the imidazoline receptor in a host cell are described. Also, a screening method for identifying drugs that interact with the imidazoline receptor is described.
    Type: Grant
    Filed: May 20, 1996
    Date of Patent: January 18, 2000
    Assignee: The University of Mississippi Medical Center
    Inventors: John E. Piletz, Tina R. Ivanov