Patents by Inventor Tindy Li

Tindy Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nrf2 REGULATORS
    Publication number: 20230047296
    Abstract: The present invention relates to aryl analogs, pharmaceutical compositions containing them and their use as NRF2 regulators.
    Type: Application
    Filed: October 6, 2021
    Publication date: February 16, 2023
    Inventors: Jeffrey K. KERNS, James Callahan, Hongxing Yan, Thomas Daniel Heightman, Charlotte Mary Griffiths-Jones, Alison Jo-Anne Woolford, Tindy Li, Ami Lakdawala Shah, Roderick S. Davis, David Norton, Jeffrey Charles Boehm, Paris L. Hamilton, Nicole Cathleen Goodwin, Yun Jin
  • BISARYL LACTAMS AS NRF2 ACTIVATORS
    Publication number: 20220002272
    Abstract: The present invention relates to bisaryl lactam compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators.
    Type: Application
    Filed: December 11, 2017
    Publication date: January 6, 2022
    Inventors: Jeffrey Charles BOEHM, Roderick S. DAVIS, Nicole Cathleen GOODWIN, Jeffrey K. KERNS, Tindy LI, Hongxing YAN
  • Nrf2 REGULATORS
    Publication number: 20200079759
    Abstract: The present invention relates to aryl analogs, pharmaceutical compositions containing them and their use as NRF2 regulators.
    Type: Application
    Filed: November 6, 2019
    Publication date: March 12, 2020
    Inventors: Jeffrey K. KERNS, James Callahan, Hongxing Yan, Thomas Daniel Heightman, Charlotte Mary Griffiths-Jones, Alison Jo-Anne Woolford, Tindy Li, Ami Lakdawala Shah, Roderick S. Davis, David Norton, Jeffrey Charles Boehm, Paris L. Hamilton, Nicole Cathleen Goodwin, Yun Jin
  • Biaryl pyrazoles as NRF2 regulators
    Patent number: 10364256
    Abstract: The present invention relates to biaryl pyrazole compounds of Formula (I) methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: July 30, 2019
    Assignees: GlaxoSmithKline Intellectual Property Development Limited, Astex Therapeutics Limited
    Inventors: James Callahan, Jeffrey K. Kerns, Peng Li, Tindy Li, Brent W. McCleland, Hong Nie, Joseph E. Pero, Thomas Glanmor Davies, Maria Grazia Carr, Charlotte Mary Griffiths-Jones, Thomas Daniel Heightman, David Norton, Marinus Leendert Verdonk, Alison Jo-Anne Woolford, Hendrika Maria Gerarda Willems
  • Arylcyclohexyl pyrazoles as NRF2 regulators
    Patent number: 10351530
    Abstract: The present invention relates to arylcyclohexyl pyrazole compounds of Formula (I) methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: July 16, 2019
    Assignees: GlaxoSmithKline Intellectual Property Development Limited, Astex Therapeutics Limited
    Inventors: James Callahan, Jeffrey K. Kerns, Tindy Li, Brent W. McCleland, Hong Nie, Joseph E. Pero, Thomas Glanmor Davies, Charlotte Mary Griffiths-Jones, Thomas Daniel Heightman, Steven Howard, David Norton, Marinus Leendert Verdonk, Alison Jo-Anne Woolford
  • NRF2 Regulators
    Publication number: 20190002454
    Abstract: The present invention relates to bis aryl analogs, pharmaceutical compositions containing them and their use as Nrf2 regulators.
    Type: Application
    Filed: September 6, 2018
    Publication date: January 3, 2019
    Inventors: Jeffrey Charles BOEHM, Thomas Glanmor DAVIES, Alison Jo-Anne WOOLFORD, Charlotte Mary GRIFFITHS-JONES, Hendrika Maria Gerarda WILLEMS, David NORTON, Gordon SAXTY, Thomas Daniel HEIGHTMAN, Tindy LI, Jeffrey K. KERNS, Roderick S. DAVIS, Hongxing YAN
  • ARYLCYCLOHEXYL PYRAZOLES AS NRF2 REGULATORS
    Publication number: 20180282283
    Abstract: The present invention relates to arylcyclohexyl pyrazole compounds of Formula (I) methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators.
    Type: Application
    Filed: October 6, 2016
    Publication date: October 4, 2018
    Inventors: James CALLAHAN, Jeffrey K. KERNS, Tindy LI, Brent W. McCLELAND, Hong NIE, Joseph E. PERO, Thomas Glanmor DAVIES, Charlotte Mary GRIFFITHS-JONES, Thomas Daniel HEIGHTMAN, Steven HOWARD, David NORTON, Marinus Leendert VERDONK, Alison Jo-Anne WOOLFORD
  • BIARYL PYRAZOLES AS NRF2 REGULATORS
    Publication number: 20180282349
    Abstract: The present invention relates to biaryl pyrazole compounds of Formula (I) methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators.
    Type: Application
    Filed: October 6, 2016
    Publication date: October 4, 2018
    Inventors: James CALLAHAN, Jeffrey K. KERNS, Peng LI, Tindy LI, Brent W. McCLELAND, Hong NIE, Joseph E. PERO, Thomas Glanmor DAVIES, Maria GRAZIA CARR, Charlotte Mary GRIFFITHS-JONES, Thomas Daniel HEIGHTMAN, David NORTON, Marinus Leedert VERDONK, Alison Jo-Anne WOOLFORD, Hendrika Maria Gerarda WILLEMS
  • Nrf2 REGULATORS
    Publication number: 20180179187
    Abstract: Provided are aryl analogs, pharmaceutical compositions containing them and their use as NRF2 regulators.
    Type: Application
    Filed: June 15, 2016
    Publication date: June 28, 2018
    Inventors: Jeffrey K. KERNS, James CALLAHAN, Hongxing YAN, Thomas Daniel HEIGHTMAN, Charlotte Mary GRIFFITHS-JONES, Alison Jo-Anne WOOLFORD, Tindy LI, Ami Lakdawala SHAH, Roderick S. DAVIS, David NORTON, Jeffrey Charles BOEHM, Paris L. HAMILTON
  • Nrf2 REGULATORS
    Publication number: 20180179167
    Abstract: The present invention relates to aryl analogs Formula (I), pharmaceutical compositions containing them and their use as Nrf2 regulators.
    Type: Application
    Filed: June 15, 2016
    Publication date: June 28, 2018
    Inventors: Jeffrey K. KERNS, Tindy LI, Hongxing YAN, Thomas Daniel HEIGHTMAN, Alison Jo-Anne WOOLFORD, Charlotte Mary GRIFFITHS-JONES, Hendrika Maria Gerarda WILLEMS
  • NRF2 REGULATORS
    Publication number: 20160318917
    Abstract: The present invention relates to bis aryl analogs, pharmaceutical compositions containing them and their use as Nrf2 regulators.
    Type: Application
    Filed: December 17, 2014
    Publication date: November 3, 2016
    Inventors: Jeffrey Charles Boehm, Thomas Glanmor Davies, Alison Jo-anne Woolford, Charlotte Mary Griffiths-Jones, Hendrika Maria Gerarda Willems, David Norton, Gordon Saxity, Thomas Daniel Heightman, Tindy Li, Jeffrey K. Kerns, Roderick S. Davis, Hongxing Yan
  • Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
    Patent number: 8829185
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: September 9, 2014
    Assignee: Bayer HealthCare LLC
    Inventors: Julie A. Dixon, Steven Magnuson, Barton Phillips, Yamin Wang, Tindy Li, Kyle Parcella, Jason Newcom, Harold C. E. Kluender, Zhenqiu Hong, Brent Chandler, Zhonghua Zhang, Kristen M. Allegue, Zhen Liu
  • SUBSTITUTED 4-AMINO-PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS
    Publication number: 20120165314
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Application
    Filed: March 7, 2012
    Publication date: June 28, 2012
    Applicant: Bayer HealthCare LLC
    Inventors: Julie Dixon, Barton Phillips, Yamin Wang, Tindy Li, Kyle Parcella, Jason Newcom, Harold C.E. Kluender, Zhenqiu Hong, Brent Chandler, Zhonghua Zhang, Steven Magnuson, Kristen M. Allegue, Zheng Liu
  • Indane amides
    Publication number: 20090247590
    Abstract: The invention relates to novel compounds and processes for their preparation and their use for preparing medicaments for the treatment of disorders, especially hyper-proliferative disorders.
    Type: Application
    Filed: October 14, 2005
    Publication date: October 1, 2009
    Applicant: Bayer Pharmaceuticlas Corporation
    Inventors: Yamin Wang, Tindy Li, Eric Mull
  • 1,8 Naphthyridine derivatives and their use to treat diabetes and related disorders
    Patent number: 7109196
    Abstract: The invention relates generally to naphthyridine derivatives of the formula wherein one of U, X, Y and Z is nitrogen and the others are C—R, where R is hydrogen or a substituent. More specifically, the invention relates to 1,8-naphthyridine derivatives and pharmaceutical compositions containing such derivatives. Methods of the invention comprise administration of a naphthyridine derivative of the invention for the treatment of diabetes and related disorders.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: September 19, 2006
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Yamin Wang, William H. Bullock, David E. Gunn, Qingjie Liu, Sidney X. Liang, Donglei Liu, Steven R. Magnuson, Tindy Li, Eric S. Mull, Jill E. Wood, Ning Qi
  • 1, 8-Naphthyridine derivatives and their use to treat diabetes and related disorders
    Publication number: 20060189609
    Abstract: The invention relates generally to naphthyridine derivatives of the formula wherein one of U, X, Y and Z is nitrogen and the others are C—R, where R is hydrogen or a substituent. More specifically, the invention relates to 1,8-naphthyridine derivatives and pharmaceutical compositions containing such derivatives. Methods of the invention comprise administration of a naphthyridine derivative of the invention for the treatment of diabetes and related disorders.
    Type: Application
    Filed: April 21, 2006
    Publication date: August 24, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Yamin Wang, William Bullock, David Gunn, Qingjie Liu, Sidney Liang, Donglei Liu, Steven Magnuson, Tindy Li, Eric Mull, Jill Wood, Ning Qi
  • Hydroxamic acids useful in the treatment of hyper-proliferative disorders
    Publication number: 20060063760
    Abstract: This invention relates to a compound of Formula (I) and its use in treating hyper-proliferative disorders.
    Type: Application
    Filed: April 16, 2004
    Publication date: March 23, 2006
    Applicant: BAYER PHARMACEUTICALS CORPORATION
    Inventors: Yamin Wang, Maio Dai, Holia Hatoum-Mokdad, Zhengqiu Hong, Harold Kluender, Gaetan Ladouceur, Tindy Li, Derek Lowe, Eric Mull, Tatiana Shelekhin, Roger Smith, Wai Wong
  • 1,8-Naphthyridine derivatives and their use to treat diabetes and related disorders
    Patent number: 6900205
    Abstract: The invention relates generally to naphthyridine derivatives of the formula wherein one of U, X, Y and Z is nitrogen and the others are C—R, where R is hydrogen or a substituent. More specifically, the invention relates to 1,8-naphthyridine derivatives and pharmaceutical compositions containing such derivatives. Methods of the invention comprise administration of a naphthyridine derivative of the invention for the treatment of diabetes and related disorders.
    Type: Grant
    Filed: September 23, 2002
    Date of Patent: May 31, 2005
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Yamin Wang, William H. Bullock, David E. Gunn, Qingjie Liu, Sidney X. Liang, Donglei Liu, Steven R. Magnuson, Tindy Li, Eric S. Mull, Jill E. Wood, Ning Qi
  • 1,8 Naphthyridine derivatives and their use to treat diabetes and related disorders
    Publication number: 20040209866
    Abstract: The invention relates generally to naphthyridine derivatives of the formula 1
    Type: Application
    Filed: April 28, 2004
    Publication date: October 21, 2004
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Yamin Wang, William H. Bullock, David E. Gunn, Qingjie Liu, Sideny X. Liang, Donglei Liu, Steven R. Magnuson, Tindy Li, Eric S. Mull, Jill E. Wood, Ning Qi
  • 1,8-Naphthyridine derivatives and their use to treat diabetes and related disorders
    Publication number: 20040014751
    Abstract: The invention relates generally to naphthyridine derivatives of the formula 1
    Type: Application
    Filed: September 23, 2002
    Publication date: January 22, 2004
    Inventors: Yamin Wang, William H. Bullock, David E. Gunn, Qingjie Liu, Sidney X. Liang, Donglei Liu, Steven R. Magnuson, Tindy Li, Eric S. Mull, Jill E. Wood, Ning Qi