Patents by Inventor Tine Nygaard Vinther

Tine Nygaard Vinther has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Insulins with polar recombinant extensions
    Patent number: 11208452
    Abstract: The present invention relates to novel insulins or insulins analogues that are extended with predominantly sequences of polar amino acid residues in order to improve the half-life and stability of the drug substance. The invention also provides pharmaceutical compositions comprising such drug substances, and relates to the use of such drug substances for the treatment or prevention of medical conditions relating to diabetes.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: December 28, 2021
    Assignee: Novo Nordisk A/S
    Inventors: Thomas Boerglum Kjeldsen, Thomas Hoeg-Jensen, Tine Nygaard Vinther, Frantisek Hubalek, Ingrid Pettersson
  • INSULINS WITH POLAR RECOMBINANT EXTENSIONS
    Publication number: 20180291076
    Abstract: The present invention relates to novel insulins or insulins analogues that are extended with predominantly sequences of polar amino acid residues in order to improve the half-life and stability of the drug substance. The invention also provides pharmaceutical compositions comprising such drug substances, and relates to the use of such drug substances for the treatment or prevention of medical conditions relating to diabetes.
    Type: Application
    Filed: June 2, 2016
    Publication date: October 11, 2018
    Inventors: Thomas Boerglum Kjeldsen, Thomas Hoeg-Jensen, Tine Nygaard Vinther, Frantisek Hubalek, Ingrid Pettersson
  • Human insulin analogues and derivatives comprising cysteine substitutions
    Patent number: 9187547
    Abstract: The present invention relates to human insulin analogues containing a substituting cysteine, to human insulin derivatives containing a PEGylated substituting cysteine and methods of making such. The compounds of the invention may be useful for the treatment of diabetes.
    Type: Grant
    Filed: March 15, 2012
    Date of Patent: November 17, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Tine Nygaard Vinther, Thomas Boerglum Kjeldsen, Frantisek Hubalek, Knud J. Jensen
  • Human insulin containing additional disulfide bonds
    Patent number: 8883722
    Abstract: The present invention is related to human insulin containing additional disulfide bonds and methods of making such.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: November 11, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Frantisek Hubalek, Tine Nygaard Vinther, Thomas Boerglum Kjeldsen, Svend Ludvigsen
  • Human Insulin Analogues and Derivatives Comprising Cysteine Substitutions
    Publication number: 20140031279
    Abstract: The present invention relates to human insulin analogues containing a substituting cysteine, to human insulin derivatives containing a PEGylated substituting cysteine and methods of making such. The compounds of the invention may be useful for the treatment of diabetes.
    Type: Application
    Filed: March 15, 2012
    Publication date: January 30, 2014
    Applicants: UNIVERSITY OF COPENHAGEN, NOVO NORDISK A/S
    Inventors: Tine Nygaard Vinther, Thomas Boerglum Kjeldsen, Frantisek Hubalek, Knud J. Jensen
  • Human Insulin Containing Additional Disulfide Bonds
    Publication number: 20130178414
    Abstract: The present invention is related to human insulin containing additional disulfide bonds and methods of making such.
    Type: Application
    Filed: June 21, 2011
    Publication date: July 11, 2013
    Applicant: NOVO NORDISK A/S
    Inventors: Frantisek Hubalek, Tine Nygaard Vinther, Thomas Boerglum Kjeldsen, Svend Ludvigsen