Abstract: A semiconductor device includes a fin structure. A source/drain region is formed on the fin structure. A first gate structure is disposed over the fin structure. A source/drain contact is disposed over the source/drain region. The source/drain contact has a protruding segment that protrudes at least partially over the first gate structure. The source/drain contact electrically couples together the source/drain region and the first gate structure.

Abstract: The present invention relates to a technology to provide segmental aneuploidy progeny strains of Trichoderma reesei. In particular, the present invention relates to a method to produce segmental aneuploidy progeny strains of Trichoderma reesei via sexual crossing of two parent haploid strains with chromosome heterozygosity (e.g. one having scaffold M and scaffold 33, the other having scaffold F and scaffold X), preferably at least one of which includes a non-homologous end joining (NHEJ) gene. The present invention also relates to stable, segmental aneuploidy progeny strains of richoderma reesei thus produced which particularly exhibit enhanced gene expression or activities of carbohydrate-active enzymes (CAZymes) and more particularly prevent returning to euploidy for an extended period of time.

Abstract: The present invention relates to a female fertile variant strain of filamentous fungus derived from a female sterile parental strain which comprises at least one of the six female fertility specific gene alleles or derivatives thereof comprising the functional characteristics of these alleles (FS_4-9).

Abstract: The present invention relates to a technology to provide segmental aneuploidy progeny strains of Trichoderma reesei. In particular, the present invention relates to a method to produce segmental aneuploidy progeny strains of Trichoderma reesei via sexual crossing of two parent haploid strains with chromosome heterozygosity (e.g. one having scaffold M and scaffold 33, the other having scaffold F and scaffold X), preferably at least one of which includes a non-homologous end joining (NHEJ) gene. The present invention also relates to stable, segmental aneuploidy progeny strains of richoderma reesei thus produced which particularly exhibit enhanced gene expression or activities of carbohydrate-active enzymes (CAZymes) and more particularly prevent returning to euploidy for an extended period of time.

Abstract: A method for producing picornaviral capsid protein complexes (e.g., picornavirus like particles) in E. coli using a small-ubiquitin-related fusion protein expression system and an E. coli strain used in practicing this method. Also disclosed is use of the picornaviral capsid protein complexes like thus prepared for eliciting immune responses.

Abstract: A method for producing picornaviral capsid protein complexes (e.g., picornavirus like particles) in E. coli using a small-ubiquitin-related fusion protein expression system and an E. coli strain used in practicing this method. Also disclosed is use of the picornaviral capsid protein complexes like thus prepared for eliciting immune responses.

Abstract: A simple and efficient SUMO fusion protein expression system for producing native proteins.

Abstract: A method for producing picornaviral capsid protein complexes (e.g., picornavirus like particles) in E. coli using a small-ubiquitin-related fusion protein expression system and an E. coli strain used in practicing this method. Also disclosed is use of the picornaviral capsid protein complexes like thus prepared for eliciting immune responses.

Abstract: A cis-TEVP fusion protein including a TEVP protease, a TEVP cleavage site and a target protein provide a platform for expression of the target protein. A trans-TEVP fusion protein including a TEVP cleavage site and a target protein, the amino-terminal portion of the target protein adjacent to the C-terminal portion of the TEVP cleavage site, the amino acidic residue in position P2 of the TEVP cleavage site being a Valine also produces the target protein by the same process. A cis-TEVP fusion protein system comprising the first fusion protein and a suitable host cell; a trans-TEVP fusion protein system comprising the second fusion protein and a suitable host cell; associated methods to produce target proteins, and kits of parts are also disclosed herein.

Abstract: A simple and efficient SUMO fusion protein expression system for producing native proteins.

Abstract: A method of producing a soluble capsid protein of a picornavirus using a novel and efficient SUMO fusion protein expression system.

Abstract: A method of making a vehicle wheel rim includes the steps of: deep drawing a metal plate to form a substantially cylindrical blank having two axially opposite first and second open end portions; roll-bending a ring portion of the cylindrical blank between the open end portions so that the ring portion is bent inwardly and substantially radially; placing into a mold the cylindrical blank that has been bent; forcing upper and lower press members respectively into the open end portions of the cylindrical blank; and forming the open end portions by pressing the open end portions against a cavity wall of the mold using lateral faces of the press members, and pressing two opposite sides of the bent ring portion to form a folded annular protrusion using end faces of the press members which are transverse to the lateral faces thereof, thereby providing a wheel rim body.

Abstract: A method for manufacturing a seamless wheel rim includes the steps of deeply drawing a pre-cut circular aluminum alloy plate into a cup-shaped embryo body, punching out the bottom surface thereof to form a hollow cylinder, then putting it into an expanding-pressing female die with an expanding die cavity at both ends thereof respectively, and finally pressing and expanding both ends of the embryo body by two sets of expanding-pressing male dies to form a seamless aluminum wheel rim in sequence.

Abstract: A vehicle wheel rim includes a wheel rim body having a tubular wall formed by deep drawing and having two opposite ends, and an annular protrusion formed as one piece with and projecting radially and inwardly from the tubular wall between the two ends. The annular protrusion has a first bent part which is bent inwardly from the tubular wall, and a second bent part which is bent outwardly from the first bent part. The first and second bent parts are flattened to abut each other. The annular protrusion further has a plurality of angularly spaced-apart through holes that extend through the first and second bent parts.

Abstract: A method for manufacturing a seamless wheel rim includes the steps: firstly, to deeply draw a pre-cut circular aluminum alloy plate into a cup-shaped embryo body, punch out the bottom surface thereof to form a hollow cylinder, then put it into an expanding-pressing female die with an expanding die cavity at both ends thereof respectively, and finally press and expand the both ends of the embryo body by two sets of expanding-pressing male dies to form a seamless aluminum wheel rim in sequence.