Abstract: The present disclosure provides for multi-specific antibodies and antigen-binding fragments thereof that bind to human MUC1 and CD16A, pharmaceutical compositions comprising said antibodies, and use of the antibodies or the compositions for treating a disease, such as cancer.

Abstract: The present disclosure provides for multi-specific antibodies and antigen-binding fragments thereof that bind to human CLDN6 and CD3, a pharmaceutical composition comprising said antibody or antigen-binding fragments thereof, and use of the multi-specific antibody or antigen-binding fragments thereof or the composition for treating a disease, such as cancer.

Abstract: The present disclosure provides for antibodies and antigen-binding fragments thereof that bind to human CLDN6, a pharmaceutical composition comprising said antibody or antigen-binding fragments thereof, and use of the antibody or antigen-binding fragments thereof or the composition for treating a disease, such as cancer.

Abstract: Provided are a point cloud attribute prediction method and prediction device based on a filter. The method comprises a coding method and a decoding method, and the device comprises a coding device and a decoding device. The method comprises: determining K nearest neighbor points of the current point; determining a filter matrix; and determining an attribute prediction value of the current point according to the filter matrix. Therefore, the compression performance of a point cloud attribute can be improved by means of selecting an appropriate filter.

Abstract: A semiconductor structure includes a substrate, and an active device and a passive device over the substrate. The active device is disposed in a first region of the substrate, and the passive device is disposed in a second region of the substrate. The semiconductor structure further includes a shielding structure and a passivation layer. The shielding structure includes a barrier layer and a ceiling layer. The barrier layer is on the passive device and the active device, and the ceiling layer is on the barrier layer. The passivation layer is under the barrier layer and covers a top surface of the passive device. An air cavity is defined by sidewalls of the barrier layer, a bottom surface of the ceiling layer, and the substrate.

Abstract: Provided are an intermediate (connexon and load combination) for preparing an antibody-drug conjugate (ADC), a preparation method therefor, and the use thereof. The connexon and load combination has a structure as represented by formula I. Formula I can be used for coupling highly hydrophobic compound loads, such as paclitaxel (PTX’), and a prepared ADC molecule has good hydrophilicity and thermal stability and can achieve a higher drug-to-antibody ratio.

Abstract: A semiconductor structure includes a substrate, and an active device and a passive device over the substrate. The active device is disposed in a first region of the substrate, and the passive device is disposed in a second region of the substrate. The semiconductor structure further includes a shielding structure and a passivation layer. The shielding structure includes a barrier layer and a ceiling layer. The barrier layer is on the passive device and the active device, and the ceiling layer is on the barrier layer. The passivation layer is under the barrier layer and covers a top surface of the passive device. An air cavity is defined by sidewalls of the barrier layer, a bottom surface of the ceiling layer, and the substrate.

Abstract: A semiconductor structure includes a substrate, a passive device and an active device over the substrate. The active device is formed in the first region of the substrate, and the passive device is formed in the second region of the substrate. The semiconductor structure further includes a passivation layer that covers the top surface of the passive device. The passivation layer has an opening that exposes the active device.

Abstract: Provided are a point cloud attribute prediction method and prediction device based on a filter. The method comprises a coding method and a decoding method, and the device comprises a coding device and a decoding device. The method comprises: determining K nearest neighbor points of the current point; determining a filter matrix; and determining an attribute prediction value of the current point according to the filter matrix. Therefore, the compression performance of a point cloud attribute can be improved by means of selecting an appropriate filter.

Abstract: A semiconductor structure includes a substrate, a passive device and an active device over the substrate. The active device is formed in the first region of the substrate, and the passive device is formed in the second region of the substrate. The semiconductor structure further includes a passivation layer that covers the top surface of the passive device. The passivation layer has an opening that exposes the active device.

Abstract: Disclosed is a hierarchical division-based point cloud attribute compression method. For point cloud attribute information, a new hierarchical division based coding scheme is proposed, wherein a frame of point cloud is adaptively divided into a “stripe-macroblock-block” hierarchical structure according to the spatial position and color distribution of the point cloud, and stripes are coded independently from one another, increasing the coding efficiency, enhancing the fault tolerance of a system and improving the performance of point cloud attribute compression. The method comprises: (1) inputting a point cloud; (2) division of a k-dimension (KD) tree structure of the point cloud; (3) continuity analysis of point cloud attribute information; (4) stripe division of the point cloud; (5) division of macroblocks and coding blocks of the point cloud; and (6) intra-frame prediction, transformation, quantification and entropy coding based on a block structure.

Abstract: Disclosed is a multi-angle adaptive intra-frame prediction-based point cloud attribute compression method. A novel block structure-based intra-frame prediction scheme is provided for point cloud attribute information, where six prediction modes are provided to reduce information redundancy among different coding blocks and improve the point cloud attribute compression performance. The method comprises: (1) inputting a point cloud; (2) performing point cloud attribute color space conversion; (3) dividing a point cloud by using a K-dimensional (KD) tree to obtain coding blocks; (4) performing block structure-based multi-angle adaptive intra-frame prediction; (5) performing intra-frame prediction mode decision; and (6) performing conversion, uniform quantization, and entropy encoding.

Abstract: Disclosed is a hierarchical division-based point cloud attribute compression method. For point cloud attribute information, a new hierarchical division based coding scheme is proposed, wherein a frame of point cloud is adaptively divided into a “stripe-macroblock-block” hierarchical structure according to the spatial position and color distribution of the point cloud, and stripes are coded independently from one another, increasing the coding efficiency, enhancing the fault tolerance of a system and improving the performance of point cloud attribute compression. The method comprises: (1) inputting a point cloud; (2) division of a k-dimension (KD) tree structure of the point cloud; (3) continuity analysis of point cloud attribute information; (4) stripe division of the point cloud; (5) division of macroblocks and coding blocks of the point cloud; and (6) intra-frame prediction, transformation, quantification and entropy coding based on a block structure.

Abstract: Disclosed is a multi-angle adaptive intra-frame prediction-based point cloud attribute compression method. A novel block structure-based intra-frame prediction scheme is provided for point cloud attribute information, where six prediction modes are provided to reduce information redundancy among different coding blocks and improve the point cloud attribute compression performance. The method comprises: (1) inputting a point cloud; (2) performing point cloud attribute color space conversion; (3) dividing a point cloud by using a K-dimensional (KD) tree to obtain coding blocks; (4) performing block structure-based multi-angle adaptive intra-frame prediction; (5) performing intra-frame prediction mode decision; and (6) performing conversion, uniform quantization, and entropy encoding.

Abstract: A headrest assembly for a chair includes a headrest unit, two spaced-apart grip frame members respectively connected to two opposite ends of the headrest unit, and two spaced-apart connection frame members respectively connected to the grip frame members. The grip frame members gradually extend away from each other from the headrest unit to the connection frame members, respectively. Each of the grip frame members extends obliquely, rearwardly and downwardly from the headrest unit in a manner of being oblique to a first vertical plane that has opposite front and rear surfaces respectively facing front and rear sides of the chair.

Abstract: The present invention uses a double exposure and double etching method to improve critical dimension uniformity. A coating layer is formed on a wafer that includes a first area and a second area. The first area and the second area are separately patterned with different processing conditions. By means of this two-stage patterning, the CD uniformity between wafer center and wafer edge is successfully improved over the conventional single-stage patterning process. The fabrication yield is thus enhanced.

Abstract: A method of manufacturing a contact is disclosed. A substrate is provided, and a first dielectric layer and a metal layer are formed thereon in sequence. A second dielectric layer is formed on the metal layer and the first dielectric layer. A bottom contact is formed in the second dielectric layer to electrically connect to the metal layer. A node contact is formed in the first and second dielectric layers. A capacitor is formed on the dielectric layer to electrically connect to the node contact, and a middle contact is formed on the second dielectric layer to electrically connect to the bottom contact. A third dielectric layer is formed on the capacitor, the middle contact and the second dielectric layer. A top contact is formed in the third dielectric layer to electrically connect to the middle contact.

Abstract: A method of manufacturing a contact is disclosed. A substrate is provided, and a first dielectric layer and a metal layer are formed thereon in sequence. A second dielectric layer is formed on the metal layer and the first dielectric layer. A bottom contact is formed in the second dielectric layer to electrically connect to the metal layer. A node contact is formed in the first and second dielectric layers. A capacitor is formed on the dielectric layer to electrically connect to the node contact, and a middle contact is formed on the second dielectric layer to electrically connect to the bottom contact. A third dielectric layer is formed on the capacitor, the middle contact and the second dielectric layer. A top contact is formed in the third dielectric layer to electrically connect to the middle contact.

Abstract: The present invention is a <CD sticker stand structure> in the purpose of providing a structure able to put a sticker on a CD quickly and accurately; in particular an alternative positioning ring that can be used for square type or larger opening stickers.

Abstract: The present invention uses a double exposure and double etching method to improve critical dimension uniformity. A coating layer is formed on a wafer that includes a first area and a second area. The first area and the second area are separately patterned with different processing conditions. By means of this two-stage patterning, the CD uniformity between wafer center and wafer edge is successfully improved over the conventional single-stage patterning process. The fabrication yield is thus enhanced.