Abstract: An automated system and method for assisting in decision making for the treatment of stroke patients is provided, and specifically for assisting a physician whether the patient should be administered a drug or transferred to another hospital to undergo an endovascular thrombectomy procedure. A variety of factors are input into the system with limited human intervention and a tool automatically determines the probability of whether the patient will have a better outcome if transferred or not. The factors include clinical factors, imaging factors and time to transfer factors. The tool includes processes for automatically determining several imaging factors, including the determination of clot length, collateral blood flow, the presence of forward blood flow within and around the clot, and the clot permeability. The tool has capability to continuously update the treatment protocol and other output results using current clinical, health system or other relevant information or feedback.

Abstract: A computer implemented method for blood flow imaging including: obtaining image data including a plurality of corresponding images capturing at least a portion of both an increase phase and a decline phase of a contrast agent in a cardiovasculature of interest; selecting a target voxel in the image data; generating a time-enhancement curve of the contrast agent based on the image data; selecting first and second time points from the time-enhancement curve; determining a rate of change of enhancement by subtraction of image data at the selected first and second time points; determining a blood flow characteristic of the target voxel based on the rate of change of enhancement. Systems and non-transitory computer-readable media for executing the method are also provided.

Abstract: A computer implemented method for dynamic angiographic imaging including: obtaining image data comprising a plurality of corresponding images capturing at least a portion of both an increase phase and a decline phase of a contrast agent in a blood vessel of interest; generating at least one time-enhancement curve of the contrast agent based on the image data; determining a blood flow characteristic in the blood vessel of interest based on the time-enhancement curve. Systems for implementing the method and computer readable media incorporating the method are also described.

Abstract: An automated system and method for assisting in decision making for the treatment of stroke patients is provided, and specifically for assisting a physician whether the patient should be administered a drug or transferred to another hospital to undergo an endovascular thrombectomy procedure. A variety of factors are input into the system with limited human intervention and a tool automatically determines the probability of whether the patient will have a better outcome if transferred or not. The factors include clinical factors, imaging factors and time to transfer factors. The tool includes processes for automatically determining several imaging factors, including the determination of clot length, collateral blood flow, the presence of forward blood flow within and around the clot, and the clot permeability. The tool has capability to continuously update the treatment protocol and other output results using current clinical, health system or other relevant information or feedback.

Abstract: An automated system and method for assisting in decision making for the treatment of stroke patients is provided, and specifically for assisting a physician whether the patient should be administered a drug or transferred to another hospital to undergo an endovascular thrombectomy procedure. A variety of factors are input into the system with limited human intervention and a tool automatically determines the probability of whether the patient will have a better outcome if transferred or not. The factors include clinical factors, imaging factors and time to transfer factors. The tool includes processes for automatically determining several imaging factors, including the determination of clot length, collateral blood flow, the presence of forward blood flow within and around the clot, and the clot permeability. The tool has capability to continuously update the treatment protocol and other output results using current clinical, health system or other relevant information or feedback.

Abstract: An automated system and method for assisting in decision making for the treatment of stroke patients is provided, and specifically for assisting a physician whether the patient should be administered a drug or transferred to another hospital to undergo an endovascular thrombectomy procedure. A variety of factors are input into the system with limited human intervention and a tool automatically determines the probability of whether the patient will have a better outcome if transferred or not. The factors include clinical factors, imaging factors and time to transfer factors. The tool includes processes for automatically determining several imaging factors, including the determination of clot length, collateral blood flow, the presence of forward blood flow within and around the clot, and the clot permeability. The tool has capability to continuously update the treatment protocol and other output results using current clinical, health system or other relevant information or feedback.

Abstract: An automated system and method for assisting in decision making for the treatment of stroke patients is provided, and specifically for assisting a physician whether the patient should be administered a drug or transferred to another hospital to undergo an endovascular thrombectomy procedure. A variety of factors are input into the system with limited human intervention and a tool automatically determines the probability of whether the patient will have a better outcome if transferred or not. The factors include clinical factors, imaging factors and time to transfer factors. The tool includes processes for automatically determining several imaging factors, including the determination of clot length, collateral blood flow, the presence of forward blood flow within and around the clot, and the clot permeability. The tool has capability to continuously update the treatment protocol and other output results using current clinical, health system or other relevant information or feedback.

Abstract: Described herein is a head cooling system comprising: a source of compressed breathable gas; a vortex tube comprising an inlet, a hot gas outlet and a cold gas outlet, the inlet operably connected to the source of compressed breathable gas; and an interface for delivering cooled gas to a nasopharyngeal cavity in fluid communication with the cold gas outlet. The head cooling system may be used in a method to reduce neurodegeneration in a subject, for example neurodegeneration from ischemia, anoxia, cardiac arrest, trauma or neurodegenerative disease. The head cooling system may also be used in a method to prophylactically protect a subject at risk of neurodegeneration, for example neurodegeneration from ischemia, anoxia, cardiac arrest, trauma or neurodegenerative disease.

Abstract: Described herein is a head cooling system comprising: a source of compressed breathable gas; a vortex tube comprising an inlet, a hot gas outlet and a cold gas outlet, the inlet operably connected to the source of compressed breathable gas; and an interface for delivering cooled gas to a nasopharyngeal cavity in fluid communication with the cold gas outlet. The head cooling system may be used in a method to reduce neurodegeneration in a subject, for example neurodegeneration from ischemia, anoxia, cardiac arrest, trauma or neurodegenerative disease. The head cooling system may also be used in a method to prophylactically protect a subject at risk of neurodegeneration, for example neurodegeneration from ischemia, anoxia, cardiac arrest, trauma or neurodegenerative disease.

Abstract: A method of processing a plurality of time separated images comprises selecting a plurality of imaging units in each image; measuring a temporal difference in each imaging unit; and selecting temporal differences above a threshold limit.

Abstract: An automated system and method for assisting in decision making for the treatment of stroke patients is provided, and specifically for assisting a physician whether the patient should be administered a drug or transferred to another hospital to undergo an endovascular thrombectomy procedure. A variety of factors are input into the system with limited human intervention and a tool automatically determines the probability of whether the patient will have a better outcome if transferred or not. The factors include clinical factors, imaging factors and time to transfer factors. The tool includes processes for automatically determining several imaging factors, including the determination of clot length, collateral blood flow, the presence of forward blood flow within and around the clot, and the clot permeability. The tool has capability to continuously update the treatment protocol and other output results using current clinical, health system or other relevant information or feedback.

Abstract: A method of processing a plurality of time separated images comprises selecting a plurality of imaging units in each image; measuring a temporal difference in each imaging unit; and selecting temporal differences above a threshold limit.

Abstract: A method of determining dynamic parameters for a plurality of sub-regions within an interrogation region comprises processing optical image data and measurements of a concentration of contrast agent entering each of the sub-regions to determine a flow-scaled impulse residue function for each of the sub-regions, and calculating dynamic parameters for each sub-region from a respective flow-scaled impulse residue function.

Abstract: A method of processing a plurality of time separated images comprises selecting a plurality of imaging units in each image; measuring a temporal difference in each imaging unit; and selecting temporal differences above a threshold limit.

Abstract: A method of processing a plurality of time separated images comprises selecting; a plurality of imaging units in each image; measuring a temporal difference in each imaging unit; and selecting temporal differences above a threshold limit.

Abstract: A method of processing a plurality of time separated images comprises selecting a plurality of imaging units in each image; measuring a temporal difference in each imaging unit; and selecting temporal differences above a threshold limit.

Abstract: A system and method of acquiring x-ray data, comprising: acquiring a series of x-ray data for generating at least one x-ray image using an x-ray detector to receive x-ray beams from an x-ray source, wherein an object being imaged is displaced along an axis, the axis extending perpendicularly through a plane defined by the x-ray beams, wherein the displacement occurs at, at least one of a constant, accelerating, and decelerating rates; varying the rate of displacement thus enabling the x-ray detector to acquire data for at least one x-ray image during accelerating or decelerating displacement; and employing current modulation.

Abstract: A system and method of acquiring x-ray data, comprising: acquiring a series of x-ray data for generating at least one x-ray image using an x-ray detector to receive x-ray beams from an x-ray source, wherein an object being imaged is displaced along an axis, the axis extending perpendicularly through a plane defined by the x-ray beams, wherein the displacement occurs at, at least one of a constant, accelerating, and decelerating rates; varying the rate of displacement thus enabling the x-ray detector to acquire data for at least one x-ray image during accelerating or decelerating displacement; and employing current modulation.