Patents by Inventor Tingting GUO
Tingting GUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12293239Abstract: Apparatus and corresponding methods for distributing tasks across various processing devices, such as servers, of a distributed computing environment are disclosed. The embodiments can batch workloads and distribute the tasks to the various processing devices for processing such as to reduce an overall processing time and costs. The embodiments may, additionally or alternatively, monitor actual processing times, and reassign tasks that fail to complete within an expected time frame.Type: GrantFiled: December 19, 2024Date of Patent: May 6, 2025Assignee: Morgan Stanley Services Group Inc.Inventors: Tingting Guo, Tushar Kaistha, Wing Yan Ip
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Publication number: 20240374738Abstract: The present disclosure belongs to the field of biomedicine, in particular to a bifunctional compound capable of degrading receptor tyrosine kinase or pharmaceutically acceptable salt, stereoisomer, solvate or polymorph thereof. This type of compound regulates downstream key proteins by degrading the receptor tyrosine kinase, especially discoidin domain receptors (DDRs), further plays a role in treating related diseases, and shows a prominent capability of inhibiting proliferation of tumor cells. A PROTAC compound developed by the present disclosure has a novel structure, excellent biological activity, and can safely and effectively inhibit or degrade a DDR1. The compound can effectively degrade or inhibit the receptor tyrosine kinase, especially the DDR1 and/or a DDR2, and can be used for treating diseases related to the DDR1 and other RTK homeostasis imbalances.Type: ApplicationFiled: June 21, 2024Publication date: November 14, 2024Inventors: Xiangdong SU, Jinxu WANG, Fei QI, Chao XIN, Yakun GAO, Tianle WEN, Tingting GUO
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Publication number: 20240082306Abstract: Provided is a chimeric antigen receptor, comprising an antigen binding region, a transmembrane domain and an intracellular signaling region. The antigen binding region comprises an antibody specifically targeting CD7, and the intracellular signaling region consists of a co-stimulatory domain, a primary signal transduction domain, and a ?C chain or intracellular region thereof. Also provided are an engineered immune cell comprising the chimeric antigen receptor and a pharmaceutical composition thereof, and use of the engineered immune cell/pharmaceutical composition for treating cancers.Type: ApplicationFiled: December 7, 2021Publication date: March 14, 2024Applicant: BIOHENG THERAPEUTICS LIMITEDInventors: Yali ZHOU, Gong CHEN, Tingting GUO, Xiaoyan JIANG, Jiangtao REN, Xiaohong HE, Yanbin WANG, Lu HAN
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Publication number: 20240052029Abstract: Provided are an ROR1-targeting antibody, and a multispecific antibody, a chimeric antigen receptor, an antibody conjugate, a pharmaceutical composition and a kit which comprise same, and the use thereof in the diagnosis/treatment/prevention of diseases associated with ROR1 expression.Type: ApplicationFiled: January 12, 2022Publication date: February 15, 2024Applicant: BIOHENG THERAPEUTICS LIMITEDInventors: Yali ZHOU, Gong CHEN, Tingting GUO, Xiaoyan JIANG, Jiangtao REN, Xiaohong HE, Yanbin WANG, Lu HAN, Guokun LI, Jing ZHANG, Huifang SUN
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Publication number: 20240043532Abstract: Provided are an NKG2A-targeting antibody, and a multispecific antibody, a chimeric receptor, an antibody conjugate, a pharmaceutical composition and a kit which comprise same, and the use thereof in the diagnosis/treatment/prevention of diseases associated with NKG2A expression.Type: ApplicationFiled: November 18, 2021Publication date: February 8, 2024Applicant: BIOHENG THERAPEUTICS LIMITEDInventors: Yali ZHOU, Gong CHEN, Xiaoyan JIANG, Tingting GUO, Jiangtao REN, Xiaohong HE, Yanbin WANG, Lu HAN
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Publication number: 20240024465Abstract: An application of collagen peptide in the preparation of an allergen preparation auxiliary material. For an allergen preparation, the auxiliary material thereof does not contain biological macromolecules, but contains the collagen peptide, avoiding the risk of potential allergies caused by the introduction of an inactive substance protein. The allergen preparation containing no biological macromolecule auxiliary materials can be stored stably for three years at room temperature. For allergic patients, the allergen preparation is a highly effective, stable and safe drug.Type: ApplicationFiled: May 28, 2021Publication date: January 25, 2024Applicant: GLALLERGEN CO., LTD.Inventors: Caiming BAI, Yan ZHOU, Liping JIAN, Tingting GUO, Min JIANG, Lixia JIA, Yonggang WEI
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Patent number: 11805783Abstract: A growth-promoting bacterial agent capable of improving content of soybean oil, preparation method, and use thereof are provided. The growth-promoting bacterial agent is fermented by a DW1 strain, the classification name of the DW1 strain is Bacillus sp., the DW1 strain is deposited in the China Center for Type Culture Collection on Jul. 16, 2021, and the deposit number is CCTCC NO: M 2021889. The growth-promoting bacterial agent of the present disclosure has the ability to dissolve insoluble phosphorus and insoluble potassium and can increase content of readily available phosphorus and readily available potassium in the soil, which has an obvious promoting effect on the growth of soybean and improves soybean yield. The growth-promoting bacterial agent of the present disclosure promotes bacteria and can significantly improve the content of soybean oil. At the same time, it has an affinity of soybean agglutinin and can agglutinate with the soybean agglutinin.Type: GrantFiled: August 26, 2022Date of Patent: November 7, 2023Assignee: ANHUI AGRICULTURAL UNIVERSITYInventors: Yuanyuan Cao, Wenfeng Al, Quande Li, Tingting Guo, Kangmiao Ou, Ke Cai, Lijuan Qiu, Xiaobo Wang, Jia Liu, Yunyu Li, Xin Ruan, Yuanyuan Xue, Yubei Huo, Ruining Deng
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Publication number: 20230080419Abstract: A growth-promoting bacterial agent capable of improving content of soybean oil, preparation method, and use thereof are provided. The growth-promoting bacterial agent is fermented by a DW1 strain, the classification name of the DW1 strain is Bacillus sp., the DW1 strain is deposited in the China Center for Type Culture Collection on Jul. 16, 2021, and the deposit number is CCTCC NO: M 2021889. The growth-promoting bacterial agent of the present disclosure has the ability to dissolve insoluble phosphorus and insoluble potassium and can increase content of readily available phosphorus and readily available potassium in the soil, which has an obvious promoting effect on the growth of soybean and improves soybean yield. The growth-promoting bacterial agent of the present disclosure promotes bacteria and can significantly improve the content of soybean oil. At the same time, it has an affinity of soybean agglutinin and can agglutinate with the soybean agglutinin.Type: ApplicationFiled: August 26, 2022Publication date: March 16, 2023Applicant: ANHUI AGRICULTURAL UNIVERSITYInventors: Yuanyuan CAO, Wenfeng AI, Quande LI, Tingting GUO, Kangmiao OU, Ke CAI, Lijuan QIU, Xiaobo WANG, Jia LIU, Yunyu LI, Xin RUAN, Yuanyuan XUE, Yubei HUO, Ruining DENG
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Patent number: 11427271Abstract: The present disclosure provides a suspension system with damping and buffering properties, comprising a suspension assembly, a wheel train assembly and a track assembly, the suspension assembly comprises a suspension lateral plate, an approach plate, a first elastic element, a tensioning assembly, a second elastic element, an oscillating arm plate and a damping element; the wheel train assembly comprises a first approach wheel, a second approach wheel, a first load-bearing wheel, a second load-bearing wheel, a track supporting wheel and an actuation wheel. A high stability of a mobile platform moving through obstacles can be realized by assembling the approach plate, the first elastic plate and the damping element into a loading and shock absorbing module in the present disclosure.Type: GrantFiled: October 22, 2021Date of Patent: August 30, 2022Inventors: Terry Bao, Tingting Guo, Hongxiu Sun
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Publication number: 20220041229Abstract: The present disclosure provides a suspension system with damping and buffering property, comprising a suspension assembly, a wheel train assembly and a track assembly, the suspension assembly comprises a suspension lateral plate, an approach plate, a first elastic element, a tensioning assembly, a second elastic element, an oscillating arm plate and a damping element; the wheel train assembly comprises a first approach wheel, a second approach wheel, a first load-bearing wheel, a second load-bearing wheel, a track supporting wheel and an actuation wheel. A high stability of a mobile platform moving through obstacles can be realized by assembling the approach plate, the first elastic plate and the damping element into a loading and shock absorbing module in the present disclosure.Type: ApplicationFiled: October 22, 2021Publication date: February 10, 2022Inventors: Terry BAO, Tingting GUO, Hongxiu SUN
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Patent number: 11155313Abstract: The present invention discloses a high-load explosion-proof driving device, including a servo motor, a reduction box, and a power take-off assembly. The power take-off assembly includes a step sleeve, a coupling, a wheel support sleeve, and a driving wheel. The step sleeve is connected to a robot body, the coupling is disposed through the step sleeve, and a bearing structure and a sealing structure are provided between the coupling and the step sleeve. The coupling is provided with a driving wheel key and a driving wheel sleeve on the left, the driving wheel key is connected to the driving wheel sleeve, and the driving wheel sleeve is connected to the driving wheel. The present invention has the following advantages: the driving device has a high protection capability, and at the same time, power transmitted from the reduction box is distributed, thereby improving loading capability of a mobile chassis.Type: GrantFiled: March 12, 2021Date of Patent: October 26, 2021Inventors: Terry Bao, Hongxiu Sun, Xibin Li, Wentao Liu, Tingting Guo, An Zheng, Lifu Duan, Linping Zhao
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Publication number: 20210245823Abstract: The present invention discloses a high-load explosion-proof driving device, including a servo motor, a reduction box, and a power take-off assembly. The power take-off assembly includes a step sleeve, a coupling, a wheel support sleeve, and a driving wheel. The step sleeve is connected to a robot body, the coupling is disposed through the step sleeve, and a bearing structure and a sealing structure are provided between the coupling and the step sleeve. The coupling is provided with a driving wheel key and a driving wheel sleeve on the left, the driving wheel key is connected to the driving wheel sleeve, and the driving wheel sleeve is connected to the driving wheel. The present invention has the following advantages: the driving device has a high protection capability, and at the same time, power transmitted from the reduction box is distributed, thereby improving loading capability of a mobile chassis.Type: ApplicationFiled: March 12, 2021Publication date: August 12, 2021Inventors: Terry BAO, Hongxiu SUN, Xibin LI, Wentao LIU, Tingting GUO, An ZHENG, Lifu DUAN, Linping ZHAO