Abstract: Method and apparatus for recommending at least one of a makeup palette or a hair coloration scheme are provided. The method comprises extracting a color set of at least one region of a digital image associated with a user (201); generating color recommendation information for at least one of a makeup palette or a hair coloration scheme for at least two other regions of the digital image associated with the user based on one or more inputs indicative of the extracted color set (202); and generating one or more instances of a virtual representation of a makeup palette recommendation or a hair coloration scheme recommendation based on the color recommendation information (203).

Abstract: The present invention provides a method for determining a quantitative measure indicative of the number of nucleic acids in a sample that map to a specific genomic region. The method involves: (a) providing a sample containing parent nucleic acids; (b) amplifying these parent nucleic acids to generate progeny nucleic acids; (c) sequencing the progeny nucleic acids to produce sequence reads; (d) grouping the sequence reads into families, where each family corresponds to sequence reads derived from the same parent nucleic acid; and (e) utilizing both the number of families mapping to the genomic region and the family size distribution of these families to calculate a quantitative measure indicative of the number of nucleic acids in the sample that map to the genomic region. This method enhances the accuracy of quantifying nucleic acids within a genomic region, particularly in complex or low-abundance samples.

Abstract: In implementations described herein, methylation information is determined with respect to classification regions of a reference genome that are related to the presence of a tumor in a subject. The methylation information can be analyzed using a number of computational techniques to provide metrics related to the presence or absence of a tumor in a given subject, including a determination of tumor fraction.

Abstract: A diffuser, an air supply device and a vacuum cleaning equipment are provided. The diffuser has a base ring member and multiple rows of stationary blades. Each row of stationary blades is disposed on an outer ring wall of the base ring member along an axial direction of the base ring member, and is arranged along a circumferential direction of the base ring member. Opposite sides of the base ring member are respectively an air-inlet side and an air-outlet side. A chord length of each stationary blade in one row is greater than or equal to the chord length of each stationary blade in a next adjacent row. The installation angle of each stationary blade in one row is smaller than or equal to the installation angle of each stationary blade in the next adjacent row.

Abstract: The present application provides a chassis, a vehicle, a device for manufacturing a vehicle and a method for manufacturing a vehicle. The chassis includes at least two movable bodies that are continuously arranged along a first preset direction, and by adjusting a position of at least one movable body in the first preset direction, a length of the chassis in the first preset direction can be changed so as to enable the chassis to adapt to the vehicle body of a different length. Since each movable body is provided at an adjacent movable body thereof with a position adjustable in a preset direction, the chassis is made into a telescopic structure that is adjustable in length. The length of the chassis can be adjusted according to the requirements to enable the chassis to adapt to the vehicle body of a different length.

Abstract: An energy storage system and a thermal management method therefor are provided. The method includes: loading a multi-agent reinforcement learning model pre-trained and optimized through a simulation environment; receiving state observation data at a current time instant; inputting the state observation data into the multi-agent reinforcement learning model for reinforcement learning and reasoning to output multi-control action information; and generating a control action information instruction based on the multi-control action information, transmitting the control action information instruction to a cooling system in the energy storage system, and performing by the cooling system, thermal management on the energy storage system in response to the control action information instruction.

Abstract: Methods and systems are provided for determining a variant of interest by analyzing sizes and sequences of cfDNA fragments obtained from a test sample. The methods and systems provided herein implement processes that synergistically combine size and sequence information, thereby improving specificity and sensitivity of assays over conventional methods.

Abstract: Disclosed are an imidazothiazole derivative, a preparation method therefor, and an application thereof. The imidazothiazole derivative has a structure represented by formula (I): R1 and R3 are each independently selected from optionally substituted five-membered to six-membered heterocyclyl containing one to two nitrogen atoms, and R2 and R4 are each independently selected from optionally substituted aryl or heteroaryl. The imidazothiazole derivative has good MNK inhibitory activity, excellent selectivity, and an excellent in vivo hypoglycemic effect, and has a wide medicinal background.

Abstract: Methods and systems are provided for differentiating between cancer variants and somatic variants originating from hematopoietic cells in a cell free DNA sample. In some embodiments, the cancer variants can be distinguished from somatic variants originating from hematopoietic cells based on fragment size distribution.

Abstract: Presented herein are techniques for identifying and/or validating sequence variants in genomic sequence data. The techniques include generating an error rate reflective of sequence errors present in the genomic sequence data. The error rate may be used to validate potential sequence variants. The error rate may be based on errors identified during consensus sequence confirmation for sequence reads associated with individual unique molecular identifiers.

Abstract: Methods and systems are provided for determining a variant of interest by analyzing sizes and sequences of cfDNA fragments obtained from a test sample. The methods and systems provided herein implement processes that synergistically combine size and sequence information, thereby improving specificity and sensitivity of assays over conventional methods.

Abstract: Methods and systems are provided for differentiating between cancer variants and somatic variants originating from hematopoietic cells in a cell free DNA sample. In some embodiments, the cancer variants can be distinguished from somatic variants originating from hematopoietic cells based on fragment size distribution.

Abstract: This disclosure provides a method, apparatus and electronic device for information processing. A specific implementation of the method includes: receiving a first setting operation performed by a first user on a first session message in a target session, wherein the first user is a member of the target session, and the first session message comprises one or more session messages in the target session; in response to the first setting operation, changing a first operation permission of at least part of members of the target session on the first session message to a second operation permission; wherein a permission scope of the second operation permission is less than a permission scope of the first operation permission.

Abstract: Presented herein are techniques for identifying and/or validating sequence variants in genomic sequence data. The techniques include generating an error rate reflective of sequence errors present in the genomic sequence data. The error rate may be used to validate potential sequence variants. The error rate may be based on errors identified during consensus sequence confirmation for sequence reads associated with individual unique molecular identifiers.

Abstract: A single winding hybrid excitation magnetic field modulation motor includes a stator, a rotor, a winding and a permanent magnet. The stator includes a stator iron core, a permanent magnet and a winding. The stator iron core includes stator teeth and stator yoke. Each stator tooth is split into an equal number of split teeth facing the air gap side. All permanent magnets are embedded in the grooves between the split teeth on the same stator tooth, the polarity of all permanent magnets located on the same stator tooth is the same, and the polarity of the permanent magnets on the adjacent stator teeth is opposite. A single non-overlapping concentrated winding is wound on all stator teeth, and DC current and AC current are simultaneously passed into each set of windings, in which field winding and permanent magnet are excited together to form hybrid excitation.

Abstract: The present application provides a splicing-screen display device which includes a display module, a processing module, a distribution module, and a driving module. The display module includes basic display modules and at least one supplementary display module arranged at joints between the basic display modules. The processing module is electrically connected to the display module. The distribution module is electrically connected to the processing module, and sends image signals to the basic display module and the supplementary display module. The driving module is arranged corresponding to the supplementary display module and electrically connected to the supplementary display module.

Abstract: Genomic insertions, duplications, and insertion/deletion (indels) account for ˜14% of human pathogenic mutations. Current gene editing methods cannot accurately or efficiently correct these abnormal genomic rearrangements, especially larger alterations (>100 bp). The presently disclosed compositions and methods accurately delete insertions/duplications and repair the deletion junction to improve the scope of gene therapies. For example, a Cas9 prime editor (PECas9) is combined with two prime editing guide RNAs (pegRNAs) targeting complementary DNA strands. PECas9 can replace an ˜1-kb genomic fragment with a desired sequence at the target site without requiring an exogenous DNA template.

Abstract: A splicing screen image display method, a related apparatus and a storage medium are provided. The method includes: obtaining a source image and resolution information of the splicing screen device, wherein the resolution information includes pixel widths of supplementary display modules, and the pixel widths are pixel sizes of the supplementary display modules in a width direction of a seam; adding frame display areas to outer edges of the source image, to form a target image corresponding to a resolution of the splicing screen device. The frame display areas are parallel to the seam, and a sum of pixel widths of the frame display areas that are parallel to each other is equal to a sum of the pixel widths of the supplementary display modules that are parallel to each other; and sending the target image to basic display modules and supplementary display modules, to display the target image.

Abstract: The present application provides a screen touch point positioning method, a device, and an electronic apparatus. The screen touch point positioning method includes: sequentially scanning each of the point positions on a screen to obtain each of the touch feature value of the point position, determining an end point coordinate; then aggregating adjacent sensed point positions of each row to touch line segments; further determining the line segment coordinates of the touch line segments; aggregating each of the touch line segments to obtain an aggregation touch region; finally determining a coordinate of a screen touch point. The embodiment of the present application solves an issue of a conventional screen touch point positioning method being complicated and time consuming.

Abstract: Provided is a dynamic projection system suitable for an automobile. The system includes a light source, a collimating lens, a first microlens array, an LCD projection source and a second microlens array, wherein the dynamic projection system further comprises a polarization grating used for separating P-polarized light and S-polarized light, and a wave plate array. The wave plate array includes a plurality of ½ wave plates arranged at intervals. The polarization grating is arranged in front of the first microlens array and the second microlens array, the ½ wave plates and the LCD projection source are arranged between the first microlens array and the second microlens array, and the ½ wave plates are arranged in front of the LCD projection source to play a role in converting one of the P-polarized light and the S-polarized light into the other one of the P-polarized light and the S-polarized light.