Abstract: Disclosed is a 5-methylchromone and the preparation method and application thereof, the 5-methylchromone has the following structure: wherein R1 and R2 are alkyl groups. The substituted chromone has the biological activity of inhibiting tyrosinase. The preparation method uses 3,5-dihydroxytoluene as a raw material, and synthesis of chromones substituted with different groups at 2-C through acylation, esterification, rearrangement and cyclization reactions, etc. The 5-methylchromone is a completely new compound in condition that R1 is —CH2CH2CH3, and R2 is —CH2CH3, or that R1 is —C(CH3)3, and R2 is H. All the compounds have obvious inhibitory activity against tyrosinase, and can be used to prepare tyrosinase inhibitors or whitening agents.

Abstract: A computer-implemented method for drilling a wellbore in a subsurface formation. The method comprises obtaining measurement data including a first measurement from a first sensor and a second measurement from a second sensor of a drilling assembly in the wellbore. The method comprises generating, based on the first measurement, a first control point indicating a geological feature and having a first confidence interval. The method comprises generating, based on the second measurement, a second control point indicating the geological feature and having a second confidence interval. The method comprises generating a curve indicating a formation bed boundary of the subsurface formation based on the first and second control points and the first and second confidence intervals. The method comprises performing a drilling operation in the wellbore based on the formation bed boundary.

Abstract: A method for forming a model of a bottom hole assembly (BHA) in a borehole, wherein the BHA is connected to a drill string. The method may further comprise segmenting the model into one or more segments and solving a multipoint boundary value problem (BVP) based at least in part on the one or more segments.

Abstract: A method for forming a model of a bottom hole assembly (BHA) in a borehole, wherein the BHA is connected to a drill string. The method may further comprise segmenting the model into one or more segments and solving a multipoint boundary value problem (BVP) based at least in part on the one or more segments.

Abstract: In the technical field of plant medicines, disclosed is the application of aloesin in the preparation of products for preventing or treating obesity. Research has found that aloesin can inhibit lipid accumulation, increase the expression of browning genes UCP1 and PRDM16 and transcription factor C-EBPa, increase the expression and release of specific factor adiponectin, and inhibit the release of non-specific factor IL-1?, indicating that aloesin can mediate the browning of 3T3-L1 adipocytes, and aloesin can be used to prepare products for preventing or treating obesity.

Abstract: A method for downhole measurement operations. The method may include taking one or more measurements with a sensor disposed in a bottom hole assembly, converting the one or more measurements into one or more revolutions-per-minute (RPM) measurements, identifying one or more frequency components of the one or more RPM measurements using a Fast Fourier Transform, identifying one or more peaks of the one or more frequency components, and identifying torsional oscillation based at least in part on the one or more peaks. The method may be performed on a non-transitory computer-readable tangible medium comprising executable instructions that cause a computer device to take one or more signal measurements, identify one or more frequency components of the one or more signal measurements using a Fast Fourier Transform, and identify one or more peaks of the one or more frequency components.

Abstract: Disclosed is a 5-methylchromone and the preparation method and application thereof, the 5-methylchromone has the following structure: wherein R1 and R2 are alkyl groups. The substituted chromone has the biological activity of inhibiting tyrosinase. The preparation method uses 3,5-dihydroxytoluene as a raw material, and synthesis of chromones substituted with different groups at 2-C through acylation, esterification, rearrangement and cyclization reactions, etc. The 5-methylchromone is a completely new compound in condition that R1 is —CH2CH2CH3, and R2 is —CH2CH3, or that R1 is —C(CH3)3, and R2 is H. All the compounds have obvious inhibitory activity against tyrosinase, and can be used to prepare tyrosinase inhibitors or whitening agents.

Abstract: The present invention discloses a primer combination for detecting 9 NA subtype AIVs and an application thereof. The present invention protects a primer combination comprising 10 primer pairs (20 primers), and the 20 primers are set forth in SEQ ID NO: 1 to SEQ ID NO: 20 of the Sequence Listing in sequence. When used for identifying 9 NA subtypes, a GeXP detection method in combination with the primer combination provided by the present invention has the advantages of high throughput, fast, time-saving and labor-saving. The present invention provides an effective method for rapid identification of 9 different NA subtype AIVs and has a broad application prospect.

Abstract: The present invention provides a method and system for urban impervious surface extraction based on remote sensing. The method includes: acquiring Landsat data; preprocessing the Landsat data to obtain preprocessed remotely sensed data; separately calculating an NDUI, an MNDWI, and a SAVI based on the remotely sensed data; stretching the NDUI, the MNDWI, and the SAVI to obtain a stretched NDUI, MNDWI, and SAVI; calculating an NDUII based on the stretched NDUI, MNDWI, and SAVI; and extracting impervious surface information by using a thresholding method based on the NDUII. The present invention can improve impervious surface extraction accuracy.

Abstract: The present invention discloses a primer combination for detecting 9 NA subtype AIVs and an application thereof. The present invention protects a primer combination comprising 10 primer pairs (20 primers), and the 20 primers are set forth in SEQ ID NO: 1 to SEQ ID NO: 20 of the Sequence Listing in sequence. When used for identifying 9 NA subtypes, a GeXP detection method in combination with the primer combination provided by the present invention has the advantages of high throughput, fast, time-saving and labor-saving. The present invention provides an effective method for rapid identification of 9 different NA subtype AIVs and has a broad application prospect.

Abstract: Provided herein are a GeXP rapid detection primer set for simultaneously identifying gene HA of eight different human-infected subtypes of avian influenza virus, a kit, and use thereof. Disclosed are 9 pairs of specific primer and 1 pair of universal primer, for a GeXP rapid detection primer kit for simultaneously identifying gene HA of eight different human-infected subtypes of avian influenza virus. Eight different human-infected subtypes HA of avian influenza virus from the nine genes of M, H1, H2, H3, H5, H6, H7, H9 and H10 can be identified simultaneously with a sensitivity of 102 copies/?L.

Abstract: The present disclosure discloses a primer combination and GeXP detection method for simultaneously identifying eight kinds of bovine pathogens. The primer combination of the present disclosure consists of primer pair I, primer pair II, primer pair III, primer pair IV, primer pair, primer pair VI, primer pair VII and primer pair VIII. The present disclosure also discloses a GeXP detection method that can simultaneously identify bovine infectious diseases of foot-and-mouth disease virus, bluetongue virus, vesicular stomatitis virus, bovine viral diarrhea virus, bovine rotavirus, enterotoxigenic E. coli, infectious bovine rhinotracheitis virus and peste des petits ruminants virus. The GeXP detection method established can simultaneously identify the eight pathogens of bovine infectious diseases.

Abstract: Provided herein are a GeXP rapid detection primer set for simultaneously identifying gene HA of eight different human-infected subtypes of avian influenza virus, a kit, and use thereof. Disclosed are 9 pairs of specific primer and 1 pair of universal primer, for a GeXP rapid detection primer kit for simultaneously identifying gene HA of eight different human-infected subtypes of avian influenza virus. Eight different human-infected subtypes HA of avian influenza virus from the nine genes of M, H1, H2, H3, H5, H6, H7, H9 and H10 can be identified simultaneously with a sensitivity of 102 copies/?L.