Abstract: The present disclosure relates to a chimeric influenza virus hemagglutinin (HA) polypeptide, comprising one or more stem domain sequence, each having at least 60% homology with a stem domain consensus sequence of H1 subtype HA (H1 HA) and/or H5 subtype HA (H5 HA), fused with one or more globular head domain sequence, each having at least 60% homology with a globular head domain consensus sequence of H1 subtype HA (H1 HA) or H5 subtype HA (H5 HA).

Abstract: The present disclosure relates to a chimeric influenza virus hemagglutinin (HA) polypeptide, comprising one or more stem domain sequence, each having at least 60% homology with a stem domain consensus sequence of H1 subtype HA (H1 HA) and/or H5 subtype HA (H5 HA), fused with one or more globular head domain sequence, each having at least 60% homology with a globular head domain consensus sequence of H1 subtype HA (H1 HA) or H5 subtype HA (H5 HA).

Abstract: A device includes: a complementary transistor including: a first transistor having a first source/drain region and a second source/drain region; and a second transistor stacked on the first transistor, and having a third source/drain region and a fourth source/drain region, the third source/drain region overlapping the first source/drain region, the fourth source/drain region overlapping the second source/drain region. The device further includes: a first source/drain contact electrically coupled to the third source/drain region; a second source/drain contact electrically coupled to the second source/drain region; a gate isolation structure adjacent the first and second transistors; and an interconnect structure electrically coupled to the first source/drain contact and the second source/drain contact.

Abstract: Provided is a composition of antiviral agent for use in prophylaxis or treatment against pathogenic infection. The liposomal antiviral agent of the composition has a liposome and an antiviral agent entrapped in the liposome. The antiviral agent has been stably encapsulated in the liposome, and the resulting liposomal antiviral agent is proven to be stably aerosolized or nebulized for administration via the inhalation route to treat a subject in need thereof with reduced side effect.

Abstract: Provided is a liposomal sustained-release composition for use in treatment of pulmonary disease. The liposomal sustained release composition comprises a liposome that includes a polyethylene glycol (PEG)-modified lipid and encapsulates a tyrosine kinase inhibitor. Tyrosine kinase inhibitor is stably entrapped in the liposome, and the resulting liposomal drug formulation can be aerosolized or nebulized for administration via inhalation. This aerosolized liposomal drug formulation yields consistent pharmacokinetic and pharmacodynamic profiles while achieving desired efficacy and safety.

Abstract: Provided is a liposomal sustained-release composition for use in treatment of pulmonary disease. The liposomal sustained release composition comprises a liposome that includes a polyethylene glycol (PEG)-modified lipid and encapsulates a tyrosine kinase inhibitor. Tyrosine kinase inhibitor is stably entrapped in the liposome, and the resulting liposomal drug formulation can be aerosolized or nebulized for administration via inhalation. This aerosolized liposomal drug formulation yields consistent pharmacokinetic and pharmacodynamic profiles while achieving desired efficacy and safety.

Abstract: Provided is a liposomal sustained release composition of bronchodilator for use in treatment of pulmonary disease. The liposomal bronchodilator has a liposome containing a bronchodilator entrapped in the liposome. The bronchodilator has been stably encapsulated in the liposome, and the resulting liposomal bronchodilator is proven to be stably aerosolized or nebulized for administration via the inhalation route to treat a subject in need thereof.

Abstract: The present disclosure provides a method of adjusting a dimension of a molded product. The method includes generating a plurality of adjusted molding conditions comprising an adjusted velocity profile and an adjusted packing pressure profile; conducting, via an injection-molding apparatus, an actual molding to produce a molded product using the adjusted molding conditions if the adjusted molding condition is qualified; determining whether a dimension of the molded product needs to be adjusted; and updating at least one of the adjusted molding conditions if the dimension of the molded product needs to be adjusted.

Abstract: The present disclosure provides a method of producing a molded product. The method comprises steps of performing, via computer-assisted engineering simulation software, a first simulation process to generate a plurality of molding conditions comprising a default injection velocity profile and a default packing pressure profile; conducting, via an injection-molding apparatus, a trial molding to inject a molding material into a mold using the default molding conditions and sensing a plurality of in-mold pressures at different sites in a mold cavity of the mold; and conducting, via an injection-molding apparatus, an actual molding to produce the molded product using the default molding conditions if a deviation of the in-mold pressures at an endpoint of a packing stage is less than a target value.

Abstract: The present disclosure provides a method of producing a molded product. The method comprises steps of performing, via computer-assisted engineering simulation software, a first simulation process to generate a plurality of molding conditions comprising a default injection velocity profile and a default packing pressure profile; conducting, via an injection-molding apparatus, a trial molding to inject a molding material into a mold using the default molding conditions and sensing a plurality of in-mold pressures at different sites in a mold cavity of the mold; and conducting, via an injection-molding apparatus, an actual molding to produce the molded product using the default molding conditions if a deviation of the in-mold pressures at an endpoint of a packing stage is less than a target value.

Abstract: Provided is a liposomal sustained-release composition for use in treatment of pulmonary disease. The liposomal sustained release composition comprises a liposome that includes a polyethylene glycol (PEG)-modified lipid and encapsulates a tyrosine kinase inhibitor. Tyrosine kinase inhibitor is stably entrapped in the liposome, and the resulting liposomal drug formulation can be aerosolized or nebulized for administration via inhalation. This aerosolized liposomal drug formulation yields consistent pharmacokinetic and pharmacodynamic profiles while achieving desired efficacy and safety.

Abstract: A wide-angle lens system comprises a first lens having a concave aspheric surface and a planar surface, a second lens having a convex aspheric surface and a planar surface, a substrate, wherein the planar surface of the first lens is adjacent to a first side of the substrate and the planar surface of the second lens is adjacent to a second side of the substrate, a third lens behind the second lens having a concave aspheric surface and a planar surface, and a stop disposed between the first lens and the substrate. The planar surface of the third lens is secured to an outermost surface of an image sensor.

Abstract: A wide-angle lens system comprises a first lens having a concave aspheric surface and a planar surface, a second lens having a convex aspheric surface and a planar surface, a substrate, wherein the planar surface of the first lens is adjacent to a first side of the substrate and the planar surface of the second lens is adjacent to a second side of the substrate, a third lens behind the second lens having a concave aspheric surface and a planar surface, and a stop disposed between the first lens and the substrate. The planar surface of the third lens is secured to an outermost surface of an image sensor.

Abstract: An ultra-small camera module with wide field of view includes (a) a wafer-level lens system for forming, on an image plane, an image of a wide field-of-view scene, wherein the wafer-level lens system includes (i) a distal planar surface positioned closest to the scene and no more than 2.5 millimeters away from the image plane in direction along optical axis of the wafer-level lens system, and (ii) a plurality of lens elements optically coupled in series along the optical axis, each of the lens elements having a curved surface, and (b) an image sensor mechanically coupled to the wafer-level lens system and including a rectangular array of photosensitive pixels, positioned at the image plane, for capturing the image, wherein cross section of the ultra-small camera module, orthogonal to the optical axis, is rectangular with side lengths no greater than 1.5 millimeters.

Abstract: An ultra-small camera module with wide field of view includes (a) a wafer-level lens system for forming, on an image plane, an image of a wide field-of-view scene, wherein the wafer-level lens system includes (i) a distal planar surface positioned closest to the scene and no more than 2.5 millimeters away from the image plane in direction along optical axis of the wafer-level lens system, and (ii) a plurality of lens elements optically coupled in series along the optical axis, each of the lens elements having a curved surface, and (b) an image sensor mechanically coupled to the wafer-level lens system and including a rectangular array of photosensitive pixels, positioned at the image plane, for capturing the image, wherein cross section of the ultra-small camera module, orthogonal to the optical axis, is rectangular with side lengths no greater than 1.5 millimeters.

Abstract: A method and an apparatus for one-time connection are provided. In the method, a first apparatus generates a connection item according to first connection information, in which the first connection information is previously registered in a server. Next, a second apparatus obtains the connection item and accordingly generates a virtual card. The second apparatus further uploads the virtual card and second connection information to the server to register the virtual card in the server. Then, the second apparatus receives a selecting operation for the virtual card and accordingly uploads a connection request of using the virtual card to the server. The server establishes a one-time connection between the second apparatus and the first apparatus according to the virtual card, the first connection information and the second connection information.

Abstract: Shopping methods and systems for providing real-time transaction are provided. First, product information of one or more stores neighboring to a plurality of first electronic devices are obtained and transmitted to a server by the first electronic devices. Thereafter, a product list in a database of the server is updated according to the obtained product information and the updated product list is further provided to a second electronic device by the server to enable the second electronic device to select a product therefrom and request a user of the first electronic device for providing a surrogate shopping service of buying the selected product.

Abstract: An electronic apparatus and a soft locking method thereof are provided. The method is adapted for at least one electronic apparatus. In the method, the at least one electronic apparatus is added to a group and an event is created for the at least one electronic apparatus to participate in. Next, a specific operation performed on each electronic apparatus is detected and a time that all of the at least one electronic apparatus does not detect the specific operation is accumulated. When any one of the at least one electronic apparatus detects the specific operation, the event is suspended and a suspension message is distributed. When the accumulated time reaches a predetermined value, a reward is sent to the at least one electronic apparatus participating in the event.

Abstract: A lens system and a for a capsule endoscope includes a first lens having a concave aspheric surface having a radius R2 and a second lens having a convex aspheric surface having a radius R3 facing the first lens. A third lens has a convex aspheric surface having radius R6. The lens system satisfies the following conditions: (1) R2/Gap>1 and ABS(R3/R2)>1.28; (2) 1<ABS(R6/R2)<1.1 and R6<0; and (3) V2<V1 and V2<V3; wherein: i) Gap is a distance from a center of curvature of the concave aspheric surface of the first lens to a center of curvature of the convex aspheric surface of the second lens; (ii) ABS denotes absolute value; and (iii) V1 is an Abbe number of the first lens, V2 is an Abbe number of the second lens, and V3 is an Abbe number of the third lens.