Patents by Inventor Tino Dyhring

Tino Dyhring has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-substituted quinuclidines and their use as nicotinic agonists
    Patent number: 6884807
    Abstract: This invention relates to novel 3-substituted quinuclidine derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Grant
    Filed: November 28, 2001
    Date of Patent: April 26, 2005
    Assignee: Neurosearch, A/S
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Østergaard Nielsen, Philip K. Ahring, Tino Dyhring Jørgensen
  • Heteroaryl-diazabicycloalkanes
    Patent number: 6815438
    Abstract: The present invention relates to novel heteroaryl-diazabicycloalkanes which are found to be cholinergic ligands at the nicotinic Acetyl Choline Receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neurodegeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: November 9, 2004
    Assignee: Neurosearch A/S
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Philip K. Ahring, Simon Feldbaek Nielsen, Tino Dyhring Jorgensen
  • Novel 2,5-diazabicyclo[2.2.1]heptane derivatives
    Publication number: 20040181069
    Abstract: The present invention relates to novel 2,5-diazabicyclo[2.2.1]heptane derivatives, which are found to be potent modulators of the monoamine receptors and transporters.
    Type: Application
    Filed: April 23, 2004
    Publication date: September 16, 2004
    Inventors: Dan Peters, Unnar M Olsen, Elsebet Ostergaard Nielsen, Philip K. Ahring, Tino Dyhring Gensen
  • Novel compounds, their preparation and use
    Publication number: 20040180877
    Abstract: The present invention relates to novel compounds that are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters.
    Type: Application
    Filed: December 30, 2003
    Publication date: September 16, 2004
    Inventors: Dan Peters, Gunnar M Olsen, Elsebert Ostergaard Nielsen, Philip K ahring, Tino Dyhring Jorgensen
  • Novel heteroaryl-diazabicyclo alkanes as cns-modulators
    Publication number: 20040147505
    Abstract: The present invention relates to novel diazabicycloalkane derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances. A diazabicycloalkane derivative selected from those represented by Formula I, by Formula II, by Formula III, by Formula IV, and by Formula V.
    Type: Application
    Filed: December 1, 2003
    Publication date: July 29, 2004
    Inventors: Dan Peters, Gunnar M Olsen, Elsebet Ostergaard Nielsen, Philip K Ahring, Tino Dyhring Jorgensen, Frank Abilgaard Slok
  • Novel diazabicyclic biaryl derivatives
    Publication number: 20040127491
    Abstract: This invention relates to novel diazabicyclic biaryl derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: November 10, 2003
    Publication date: July 1, 2004
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Oestergaard Nielsen, Tino Dyhring Joergensen, Philip K. Ahring
  • 3-Substituted quinuclidines and their use as nicotinic agonists
    Publication number: 20040044026
    Abstract: This invention relates to novel 3-substituted quinuclidine derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters.
    Type: Application
    Filed: May 9, 2003
    Publication date: March 4, 2004
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Philip K. Ahring, Tino Dyhring Jorgensen
  • Aryl and heteroaryl diazabicycloalkanes, their preparation and use
    Publication number: 20030176416
    Abstract: The present invention relates to novel aryl and heteroaryl diazabicycloalkane derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: November 13, 2002
    Publication date: September 18, 2003
    Inventors: Dan Peters, Gunnar M Olsen, Elsebet Ostergaard Nielsen, Philip K Ahring, Simon Feldb?aelig;k Nielsen, Tino Dyhring Jorgensen
  • Use of isatin derivatives as ion channel activating agents
    Publication number: 20030114513
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Application
    Filed: October 16, 2002
    Publication date: June 19, 2003
    Applicant: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jorgensen, Philip K. Ahring, Palle Christophersen, Dorte Strobaek, Lene Teuber, Soren Peter Olesen
  • Novel heteroaryl-diazabicycloalkanes
    Publication number: 20030004153
    Abstract: The present invention relates to novel heteroaryl-diazabicycloalkanes which are found to be cholinergic ligands at the nicotinic Acetyl Choline Receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neurodegeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: May 14, 2002
    Publication date: January 2, 2003
    Inventors: Dan Peters, Gunnar M Olsen, Elsebet Ostergaard Nielsen, Philip K Ahring, Simon Feldbaek Nielsen, Tino Dyhring Jorgensen
  • Use of isatin derivatives as ion channel activating agents
    Publication number: 20020016354
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Application
    Filed: May 15, 2001
    Publication date: February 7, 2002
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jorgensen, Philip K. Ahring, Palle Christophersen, Dorte Strobaek, Lene Teuber, Soren Peter Olesen