Patents by Inventor Tino Frank

Tino Frank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220252513
    Abstract: A filter device for an optical module for a lab-on-a-chip analysis device, in which the optical module has a light path, includes a support element, a filter support, and a drive device. The support element can be mounted in the optical module. The filter support is arranged so that it can move on the support element. The filter support also has a first filter region and a second filter region. The drive device is configured such that the filter support can move between a first position in which the first filter region is arranged in the light path, and a second position in which the second filter region is arranged in the light path.
    Type: Application
    Filed: October 18, 2019
    Publication date: August 11, 2022
    Inventors: Jochen Rupp, Robert Schreiner, Karsten Seidl, Tino Frank, Genrich Siris
  • Patent number: 11389794
    Abstract: A method for providing a solution of a substance in a microfluidic device includes providing a dispersion of a first medium and of a lyophilizate of the substance, the lyophilizate being insoluble in the first medium, and adding a second medium to the dispersion, the lyophilizate being soluble in the second medium. The method further includes dissolving the lyophilizate in the second medium such that the solution of the substance in the second medium is obtained, and separating the solution obtained by the dissolving of the lyophilizate from the first medium.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: July 19, 2022
    Assignee: Robert Bosch GmbH
    Inventor: Tino Frank
  • Patent number: 11285477
    Abstract: A method for measuring a temperature of a fluid for use with a microfluidic analysis apparatus includes a reading step and a determination step. During the reading step, at least one diffusion signal is read, the latter representing a diffusion characteristic of the diffusion of the fluid. During the determination step, the temperature is determined using the at least one diffusion signal.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: March 29, 2022
    Assignee: Robert Bosch GmbH
    Inventor: Tino Frank
  • Publication number: 20220081717
    Abstract: A method for detecting characteristic cells in a sample includes performing a first lysis of a sample to yield a first lysate wherein nuclei of the cells of the sample remain intact. Freely available RNA in the first lysate is extracted and classified to ascertain the amounts of various types of RNA in the first lysate. A second lysis operation on the previously lysed sample is performed to yield a second lysate wherein the cell nuclei of the cells in the sample are destroyed. DNA freely available in the second lysate is extracted and a total cell count of cells in the provided sample is calculated on the basis of the amount of extracted DNA. The number of cells having individual cell markers in the provided sample is calculated using the ascertained amounts of various types of RNA and the calculated total cell count.
    Type: Application
    Filed: February 27, 2020
    Publication date: March 17, 2022
    Inventors: Jochen Hoffmann, Tino Frank
  • Publication number: 20220062893
    Abstract: A method for conveying at least one first medium within a channel system of a fluidic device includes providing the at least one first medium at a first point in the channel system, conveying the at least one first medium from the first point to a second point of the channel system by means of at least one second medium which borders the at least one first medium, and altering at least one traversable cross-section of the channel system for a peristaltic pump function only at a time when the at least one first medium is not flowing through said at least one cross-section.
    Type: Application
    Filed: October 18, 2019
    Publication date: March 3, 2022
    Inventor: Tino Frank
  • Publication number: 20210396655
    Abstract: A method for analyzing biological material includes reading in a measurement signal, a first reference signal and a second reference signal. The method further includes determining noise in the measurement signal in order to produce noise data, applying the noise data to the first reference signal and to the second reference signal in order to generate an adjusted first reference signal and an adjusted second reference signal, and transforming the measurement signal, the adjusted first reference signal, and the adjusted second reference signal into a frequency distribution form in order to produce a measurement signal distribution, a first reference distribution and a second reference distribution.
    Type: Application
    Filed: November 8, 2019
    Publication date: December 23, 2021
    Inventor: Tino Frank
  • Publication number: 20210310047
    Abstract: A reaction mixture for providing a reaction batch for performing a quantitative real-time PCR contains at least one target DNA, which at least in parts corresponds to the DNA section being quantified, at least one reference DNA of defined sequence and in a defined amount, at least two different fluorescent probes of different sequence which generate a signal at different wavelengths, primers, deoxynucleotides and a DNA polymerase. The target DNA and the reference DNA have the same primer binding sites and different probe binding sites. At least one of the fluorescent probes is intended for binding to a section of the target DNA outside the primer binding sites in the amplicon, and at least one of the fluorescent probes is intended for binding to a section of the reference DNA outside the primer binding sites in the amplicon.
    Type: Application
    Filed: June 26, 2019
    Publication date: October 7, 2021
    Inventors: Sonja Kuellmer, Tino Frank
  • Publication number: 20210301323
    Abstract: A method for carrying out a process for an amplification of nucleic acids with sample nucleic acids and reference nucleic acids being amplified in separate reaction batches. Signals of the amplification are observed in real time. A number of amplification cycles and/or a duration of the amplification process are dynamically adjusted depending on the observed signals of the amplification.
    Type: Application
    Filed: July 23, 2019
    Publication date: September 30, 2021
    Inventors: Jochen Hoffmann, Tino Frank
  • Publication number: 20210293779
    Abstract: A method for actuating an analysis device for running an analysis on a sample material includes reading a user parameter, which represents an analysis to be carried out on the sample material, and loading a plurality of actuation commands for at least one analysis running unit of the analysis device from a command library. The method further includes actuating the at least one analysis running unit using the actuation commands in order to analyze the sample material.
    Type: Application
    Filed: April 18, 2019
    Publication date: September 23, 2021
    Inventors: Jochen Rupp, Tom Doehring, Karsten Seidl, Tino Frank
  • Publication number: 20210170349
    Abstract: A method for diluting, mixing, and/or aliquoting two liquids using a microfluidic system with at least two pump chambers first includes filling at least one of the at least two pump chambers with a first liquid. The at least two pump chambers are connected to one another by at least one microfluidic channel. The method then includes pumping the first liquid through the channel. The at least one channel is configured such that at least part of the first liquid remains in the channel after the pumping. The method then includes determining the part of the first liquid that remains in the channel. The method then includes flushing the channel with a second liquid.
    Type: Application
    Filed: April 9, 2019
    Publication date: June 10, 2021
    Inventors: Jochen Hoffmann, Tino Frank
  • Publication number: 20210114031
    Abstract: The disclosure relates to a method for operating a microfluidic device that includes providing at least one first medium at a first location of the microfluidic device, transporting at least one first medium from a first location to a second location of the microfluidic device, the at least one first medium being surrounded by at least one second medium in such a way that the at least one first medium only borders on the at least one second medium and on fluid boundaries of the microfluidic device or only on the at least one second medium. The at least one first medium and the at least one second medium cannot be mixed with one another.
    Type: Application
    Filed: December 19, 2018
    Publication date: April 22, 2021
    Inventor: Tino Frank
  • Publication number: 20210114024
    Abstract: A device for preparing sample material is designed as a rotary device by means of which a defined quantity of liquid can be drawn in into a sample receiving chamber for the sample material or can be expelled from the sample receiving chamber for the sample material, by means of a rotary motion.
    Type: Application
    Filed: April 24, 2019
    Publication date: April 22, 2021
    Inventors: Franz Laermer, Jochen Hoffmann, Tino Frank, Paul Kallenberger
  • Publication number: 20210069699
    Abstract: A method for providing a solution of a substance in a microfluidic device includes providing a dispersion of a first medium and of a lyophilizate of the substance, the lyophilizate being insoluble in the first medium, and adding a second medium to the dispersion, the lyophilizate being soluble in the second medium. The method further includes dissolving the lyophilizate in the second medium such that the solution of the substance in the second medium is obtained, and separating the solution obtained by the dissolving of the lyophilizate from the first medium.
    Type: Application
    Filed: December 20, 2018
    Publication date: March 11, 2021
    Inventor: Tino Frank
  • Publication number: 20210060554
    Abstract: A method for measuring a temperature of a fluid for use with a microfluidic analysis apparatus includes a reading step and a determination step. During the reading step, at least one diffusion signal is read, the latter representing a diffusion characteristic of the diffusion of the fluid. During the determination step, the temperature is determined using the at least one diffusion signal.
    Type: Application
    Filed: August 29, 2019
    Publication date: March 4, 2021
    Inventor: Tino Frank
  • Publication number: 20210053057
    Abstract: A system for introducing sample material includes a microfluidic chip and a sample feeding zone disposed on or in the microfluidic chip. The sample feeding zone is configured to introduce the sample material into the microfluidic chip.
    Type: Application
    Filed: April 24, 2019
    Publication date: February 25, 2021
    Inventors: Jochen Hoffmann, Tino Frank, Christoph Faigle
  • Publication number: 20210046481
    Abstract: A microfluidic device includes a chamber, on two sides of which lying opposite each other in a first direction, a respective first distributor is provided in order to produce a laminar flow in the first direction. Each of the first distributors has at least one branching point, at which a channel is divided into at least two channels. The at least one branching point of the first distributor is arranged in such a way that a first connection channel is connected to a plurality of first connection points of the chamber by means of the first distributor.
    Type: Application
    Filed: February 19, 2019
    Publication date: February 18, 2021
    Inventor: Tino Frank
  • Patent number: 10553383
    Abstract: An electric fuse element for arrangement on a printed circuit board is specified. The fuse element is formed as an SMD component and has a cuboidal insulating housing, two contact elements for electrical connection to the printed circuit board and at least one support element. The contact elements are arranged on a bottom side of the insulating housing, wherein the contact elements emerge at the bottom side of the insulating housing by way of a subregion, which has a contact area on the end side. The emerging subregion having the contact areas is of angled form.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: February 4, 2020
    Assignee: LEONI Bordnetz-Systeme GmbH
    Inventors: Michael Dauer, Tino Frank
  • Publication number: 20190066960
    Abstract: An electric fuse element for arrangement on a printed circuit board is specified. The fuse element is formed as an SMD component and has a cuboidal insulating housing, two contact elements for electrical connection to the printed circuit board and at least one support element. The contact elements are arranged on a bottom side of the insulating housing, wherein the contact elements emerge at the bottom side of the insulating housing by way of a subregion, which has a contact area on the end side. The emerging subregion having the contact areas is of angled form.
    Type: Application
    Filed: August 21, 2018
    Publication date: February 28, 2019
    Inventors: MICHAEL DAUER, TINO FRANK
  • Patent number: 7504579
    Abstract: A conductor routing device is configured as a drag chain and has a supply line that is conducted in a flexible cable conduit. The routing device is configured as a one-piece component including several segments that run around the supply line and that are interconnected by reinforcement struts. The reinforcement struts are arranged in a line and form a reinforcement strip in such a way that a flexural direction is defined for the cable conduit. The routing device can be bent until the outer sides of two adjacent segments touch. The segments may be ring-shaped segments.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: March 17, 2009
    Assignee: Leoni Bordnetz-Systeme GmbH
    Inventor: Tino Frank
  • Publication number: 20070084626
    Abstract: A conductor routing device is configured as a drag chain and has a supply line that is conducted in a flexible cable conduit. The device is configured as a one-piece component, comprising several segments that run around the supply line and are interconnected by reinforcement struts, which are arranged in a line and form a reinforcement strip in such a way that a flexural direction is defined for the cable conduit. The design in particular of a cast/expanded/injected module enables diverse functions to be integrated into the cable conduit and eliminates the assembly labor required to assemble the individual chain links for a conventional drag chain.
    Type: Application
    Filed: November 22, 2006
    Publication date: April 19, 2007
    Inventor: Tino Frank