Patents by Inventor Tirumala Reddy LANKI REDDY

Tirumala Reddy LANKI REDDY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMPROVED PROCESS FOR THE PREPARATION OF 7-(MORPHOLINYL)-2-(N-PIPERAZINYL)METHYLTHIENO[2, 3-C]PYRIDINE DERIVATIVES
    Publication number: 20240199637
    Abstract: The present invention describes an improved second generation process for the synthesis of NRC-1111 (1,5-[2-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-7-(4-morpholinyl)thieno[2,3-c] pyridine-5-yl]-2-pyrimidinamine) dimethane sulfonate and NRC-1109 (II, 5-[3-methyl-2-[(4-methylsulfonylpiperazin-1-yl)methyl]-7-morpholino-thieno[2,3-c]pyridin-5-yl]pyrimidin-2-amine) dimethane sulfonate. This process is cost effective, high yielding and industrially feasible process for the synthesis of compounds of formulae I and II with high purity. Formula (I) Formula (I): R?H for NRC-1111 and Formula (II): R?CH3 for NRC-1109 NRC-1111 and NRC-1109 are potential anti-cancer agents.
    Type: Application
    Filed: April 15, 2022
    Publication date: June 20, 2024
    Inventors: Amala KOMPELLA, Kameswara Rao VAGICHERLA, Tirumala Reddy LANKI REDDY, Narmada PESARU, Pulla Reddy MUDDASANI, Venkaiah Chowdary NANNAPANENI