Abstract: A system for the processing of large substrates such as those employed in the manufacture of flat panel displays is disclosed. In a first embodiment, a loadlock assembly, comprising two loadlock chambers configured to accommodate a multiplicity of large substrates, is coupled to a processing chamber with an input/output port. The processing chamber and the loadlock assembly are configured to move relative to each other to allow positioning of: either of the two loadlock chambers with said port; and any one of the multiplicity of large substrates for passage through the port. In a second embodiment, input and output loadlock assemblies, each comprising two loadlock chambers, are coupled to a dual-ported processing chamber in a pass-through configuration, wherein the input and output loadlock assemblies each move independently relative to the processing chamber.