Abstract: An acoustic focusing probe, which is an artificial periodic acoustic structure, including a background material which is water or air, and a plurality of scatterer units in a cross shape. The periodic array structure formed by scatterer units is arranged on the base, and a contour thereof is an ellipse. The present invention is based on the basic principle of controlling acoustic waves by phononic crystal and adopts a new probe structure. Compared to the existing acoustic focusing lens, the acoustic focusing probe of the present invention has a better acoustic focusing effect in various media and a wider range of low and medium frequencies. The probe can focus most of the energy of the acoustic waves to the target area, and thus it can be used in non-invasive ultrasound equipment in the future.