Abstract: An improved process for the production of maleic anhydride by the catalytic oxidation of n-butane. Maleic anhydride is produced by reacting n-butane gas with oxygen gas or an oxygen-containing gas, in the presence of a vanadium phosphorus oxide catalyst. A trialkyl phosphite or trialkyl phosphate component is continuously added to the gases in an amount of from about 0.5 ppm to about 4 ppm by weight of elemental phosphorus in the trialkyl phosphate or trialkyl phosphite component. Heat is applied to the gases at a temperature of from about 400° C. to about 440° C. while maintaining a maximum temperature of gases present in the reaction of about 480° C. A simultaneous conversion of n-butane to maleic anhydride of about 84% or more and a conversion of n-butane to by-product acrylic acid of about 1.5% or less is achieved.

Abstract: An improved process for the production of maleic anhydride by the catalytic oxidation of n-butane. Maleic anhydride is produced by reacting n-butane gas with oxygen gas or an oxygen-containing gas, in the presence of a vanadium phosphorus oxide catalyst. A trialkyl phosphite or trialkyl phosphate component is continuously added to the gases in an amount of from about 0.5 ppm to about 4 ppm by weight of elemental phosphorus in the trialkyl phosphate or trialkyl phosphite component. Heat is applied to the gases at a temperature of from about 400° C. to about 440° C. while maintaining a maximum temperature of gases present in the reaction of about 480° C. A simultaneous conversion of n-butane to maleic anhydride of about 84% or more and a conversion of n-butane to by-product acrylic acid of about 1.5% or less is achieved.

Abstract: The present invention relates to nimesulide topical formulations comprising a carboxyvinylpolymer neutralized as a gel-forming agent or a polyacrylamide-isoparaffin and a solvent selected from the group consisting of ethanol, isopropanol and diethylene glycol monoethyl ether, and to the process for the preparation thereof. Said formulations have advantages such as higher stability of the system and bioavailability of the active ingredient.

Abstract: A process for preparing a catalyst for maleic anhydride production wherein a +5 vanadium compound such as V2O5, an anhydrous phosphoric acid, and optionally promoters are admixed in an organic alcohol solvent, the admixture is rapidly brought to reflux and thereafter refluxed to reduced the vanadium compound to the desired degree, the reflux mixture is cooled, precursor crystals are separated by filtration and then dried and calcined.

Abstract: The present invention relates to nimesulide topical formulations comprising a carboxyvinylpolymer neutralized as a gel-forming agent or a polyacrylamide-isoparaffin and a solvent selected from the group consisting of ethanol, isopropanol and diethylene glycol monoethyl ether, and to the process for the preparation thereof. Said formulations have advantages such as higher stability of the system and bioavailability of the active ingredient.

Abstract: The present invention relates to nimesulide topical formulations comprising a carboxyvinylpolymer neutralized as a gel-forming agent or a polyacrylamide-isoparaffin and a solvent selected from the group consisting of ethanol, isopropanol and diethylene glycol monoethyl ether, and to the process for the preparation thereof Said formulations have advantages such as higher stability of the system and bioavailability of the active ingredient.

Abstract: Nimesulide topical formulations are provided in the form of liquid crystals. The emulsifier cetylstearyl glycoside is used, and constituents of the lipid phase such as caprylic/capric triglycerides and jojoba oil, consistence factors such as cetylstearyl alcohol. Also disclosed is a process for the preparation thereof. The formulations have advantages such as higher stability, better release and absorption of nimesulide, and a higher bioavailability of the active ingredient.