Patents by Inventor Tiziano Ferrario

Tiziano Ferrario has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of the form I of the anhydrous terazosin monohydrochloride
    Patent number: 5859245
    Abstract: The process for the production of form I of anhydrous terazosin monohydrochloride consists of heating terazosin suspended in a mixture made by methanol and a solvent selected from C.sub.2 to C.sub.6, straight or branched alcohols, esters of C.sub.1 -C.sub.8 aliphatic carboxylic acids with straight or branched C.sub.1 to C.sub.8 alcohols, C.sub.3 to C.sub.8 aliphatic ketones, C.sub.4 to C.sub.8 straight branched or cyclic aliphatic ethers, aliphatic amides and aliphatic nitriles with a methanol solution of hydrochloric acid.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: January 12, 1999
    Assignee: Alfa Chemicals Italiana S.r.l.
    Inventors: Vincenzo Cannata, Tiziano Ferrario, Barbara Galbiati
  • Process for the production of the form I of the terazosin monohydrochloride anhydrous
    Patent number: 5856482
    Abstract: The process for the production of the form I of the terazosin monohydrochloride anhydrous consists of treating at the boiling temperature terazosin monohydrochloride dihydrate with a mixture of methanol and a solvent selected from C.sub.2 -C.sub.6 straight or branched alcohols, the esters of the C.sub. -C.sub.8 carboxylic aliphatic acids with C.sub.1 -C.sub.8 straight or branched alcohols, C.sub.3 to C.sub.8 aliphatic ketones, C.sub.4 to C.sub.8 straight, branched or cyclic aliphatic ethers, aliphatic amides and the aliphatic nitriles.
    Type: Grant
    Filed: October 21, 1997
    Date of Patent: January 5, 1999
    Assignee: ALFA Chemicals Italiana S.R.L.
    Inventors: Vincenzo Cannata, Tiziano Ferrario, Barbara Galbiati
  • Process for the production of the isomers (R) and (S)-.alpha.-methyl-3(trifluoromethyl)benzeneethanamine
    Patent number: 5808156
    Abstract: Process for the production of the isomers (R) and (S)-.alpha.-methyl-3-(trifluoromethyl)benzeneethanamine, the second being useful as intermediate in the synthesis of the anorexic drug dexfenfluramine (INN), which comprises carrying out a stereospecific reductive amination of 1-(3-trifluoromethyl)phenyl-2-propanone with (R) or (S)-.alpha.-methylbenzylamine under a hydrogen atmosphere in the presence of a catalyst and debenzylating the resulting diastereoisomer (R),(R) or (S),(S)-N-(1-phenylethyl)-.alpha.-methyl-3-(trifluoromethyl)benzeneethanam ine by treatment with hydrogen and a catalyst.
    Type: Grant
    Filed: July 31, 1997
    Date of Patent: September 15, 1998
    Assignee: Alfa Chemicals Italiana S.p.A.
    Inventors: Vincenzo Cannata, Barbara Galbiati, Tiziano Ferrario