Abstract: The present disclosure relates to a magnetic-inductive flow meter including a measuring pipe having a measuring pipe body which electrically insulates portions thereof. A device generates a magnetic field that penetrates the measuring pipe body and detects an induced voltage in the medium, which is a function of a velocity of flow. A monitoring device detects damage to the measuring pipe body and comprises at least one electrically conductive conductor. The conductor is separated from the measuring pipe volume by a region of the measuring pipe body when the measuring pipe body is intact. The monitoring device comprises a measuring circuit electrically connected to the conductor and is designed to measure values of a measured variable which is dependent on an impedance of the conductor. The measuring circuit then compares each of the measured values with a reference value or a target value range.

Abstract: Provided herein are processes for the preparation of indolyl intermediates using Wenker Synthesis for the total synthesis of SERD compounds useful in the treatment of cancer.

Abstract: The present disclosure relates to a magnetic-inductive flowmeter, comprising: a measuring pipe for conducting a medium, wherein the measuring pipe comprises an electrically insulating measuring pipe body; a device for generating a magnetic field that penetrates the measuring pipe body; a device for detecting an induced voltage, which is a function of a flow rate; a reference electrode; an electrode assembly for detecting damage to the measuring pipe body, wherein the electrode assembly is electrically insulated from the reference electrode and/or the medium by the measuring pipe body; a measuring circuit configured to measure a variable that is a function of an electrical impedance between the electrode assembly and the reference electrode.

Abstract: Provided herein are processes for the preparation of compounds useful in the treatment of cancer.