Patents by Inventor Tobias Diener
Tobias Diener has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11608211Abstract: A transport packaging includes a tray formation which is configured to hold a plurality of containers with mutual separation to avoid mutual contact of the containers. The tray formation includes a first tray part having a plurality of pockets configured to receive first ends of the containers and a second tray part removably coupled to the first tray part and having a corresponding plurality of pockets configured to receive second ends of the containers. The first tray part is formed such that, when the second tray part is removed so that the second ends of the containers are free from the pockets of the second tray part, the free second ends of the containers are free to be brought into mutual contact while the first ends of the containers are still received in the pockets of the first tray part.Type: GrantFiled: July 29, 2020Date of Patent: March 21, 2023Assignee: SCHOTT Pharma Schweiz AGInventors: Arne Kloke, Rainer Landich, Michael Scheidbach, Aldin Imsic, Tobias Diener, Leah Kidney
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Publication number: 20210031980Abstract: A transport packaging includes a tray formation which is configured to hold a plurality of containers with mutual separation to avoid mutual contact of the containers. The tray formation includes a first tray part having a plurality of pockets configured to receive first ends of the containers and a second tray part removably coupled to the first tray part and having a corresponding plurality of pockets configured to receive second ends of the containers. The first tray part is formed such that, when the second tray part is removed so that the second ends of the containers are free from the pockets of the second tray part, the free second ends of the containers are free to be brought into mutual contact while the first ends of the containers are still received in the pockets of the first tray part.Type: ApplicationFiled: July 29, 2020Publication date: February 4, 2021Applicant: SCHOTT Schweiz AGInventors: Arne Kloke, Rainer Landich, Michael Scheidbach, Aldin Imsic, Tobias Diener, Leah Kidney
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Patent number: 9040069Abstract: A method for manufacturing a stationary state of polymer crystallinity of an active substance charged polylactide matrix for a stent, comprising the steps of: preparing the active substance charged polylactide matrix containing (a) a polylactide in amorphous or semicrystalline modification or with amorphous domains, and (b) at least one active substance on a surface or in a cavity of the stent communicating with the surface; and heating of the active substance charged polylactide matrix to a temperature ranging from TG-20° C. to TS-10° C., where TG represents a glass transition temperature and TS a melting temperature of the crystallites of the polylactide.Type: GrantFiled: July 7, 2006Date of Patent: May 26, 2015Assignee: BIOTRONIK VI Patent AGInventor: Tobias Diener
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Patent number: 8974521Abstract: An implant having a preferably hollow cylindrical main structure comprising a large number of continuous openings and a coating which releases at least one pharmaceutically active substance. To attain a better distribution of the pharmaceutically active substance, at least 20% of the cross-sectional area, preferably at least 50% of the cross-sectional area, of at least a portion of the openings in a predetermined section of the main structure is covered with the coating which releases at least one pharmaceutically active substance. Furthermore, a system composed of a catheter and such an implant, a simple method for manufacturing such an implant or such a system is provided.Type: GrantFiled: February 9, 2012Date of Patent: March 10, 2015Assignee: Biotronik AGInventors: Tobias Diener, Elisabeta Burean, Matthias Fringes
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Patent number: 8721712Abstract: An agent depot for mechanical connection to a surface of an endovascular implantable body, comprising one or more polymers, one or more bioactive agents, the agent depot being mechanically connectable to the implantable body by a force fit or an adhesive.Type: GrantFiled: March 28, 2011Date of Patent: May 13, 2014Assignee: Biotronik VI Patent AGInventors: Bjoern Klocke, Tobias Diener, Matthias Fringes, Claus Harder
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Patent number: 8623073Abstract: A stent comprising a degradable metal stent main body; a partition layer which is applied to the surface of the stent main body so that at least parts of the surface of the luminal side are not covered; and an agent-containing layer which is applied to the surface of the partition layer at least partially on the abluminal side of the stent main body and comprises one or more agents and possibly one or more polymers.Type: GrantFiled: July 24, 2008Date of Patent: January 7, 2014Assignee: BIOTRONIK VI Patent AGInventors: Bjoern Klocke, Tobias Diener, Matthias Fringes, Claus Harder
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Publication number: 20120220934Abstract: An implant having a preferably hollow cylindrical main structure comprising a large number of continuous openings and a coating which releases at least one pharmaceutically active substance. To attain a better distribution of the pharmaceutically active substance, at least 20% of the cross-sectional area, preferably at least 50% of the cross-sectional area, of at least a portion of the openings in a predetermined section of the main structure is covered with the coating which releases at least one pharmaceutically active substance. Furthermore, a system composed of a catheter and such an implant, a simple method for manufacturing such an implant or such a system is provided.Type: ApplicationFiled: February 9, 2012Publication date: August 30, 2012Applicant: BIOTRONIK AGInventors: Tobias Diener, Elisabeta Burean, Matthias Fringes
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Publication number: 20120109276Abstract: The present invention relates to a catheter comprising a balloon (10, 30) and at least one pharmaceutically active substance. To enable more accurate dosing of the pharmaceutically active substance, the pharmaceutically active substance is disposed in a reservoir (15, 35) inside the balloon (10, 30) or on the balloon (10, 30), wherein a wall (14, 32, 34) that closes the reservoir toward the outside comprises at least one predetermined breaking point (16). Furthermore, a system for applying an intraluminal endoprosthesis, preferably a stent, in a body cavity, and simple and cost-effective methods for manufacturing the catheter and the system are described.Type: ApplicationFiled: October 20, 2011Publication date: May 3, 2012Applicant: BIOTRONIK AGInventors: Tobias Diener, Elisabeta Burean, Matthias Fringes
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Publication number: 20110178593Abstract: An agent depot for mechanical connection to a surface of an endovascular implantable body, comprising one or more polymers, one or more bioactive agents, the agent depot being mechanically connectable to the implantable body by a force fit or an adhesive.Type: ApplicationFiled: March 28, 2011Publication date: July 21, 2011Applicant: BIOTRONIK VI PATENT AGInventors: Bjoern Klocke, Tobias Diener, Matthias Fringes, Claus Harder
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Patent number: 7913371Abstract: A method for producing an agent depot for mechanical connection to a surface of an endovascular implantable body, comprising a) providing one or more polymers; b) providing one or more agents; and c) producing an agent depot from said polymers and said agents, the agent depot being mechanically connectable to the surface of the body using force action or adhesive.Type: GrantFiled: July 21, 2008Date of Patent: March 29, 2011Assignee: Biotronik VI Patent AGInventors: Bjoern Klocke, Tobias Diener, Matthias Fringes, Claus Harder
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Publication number: 20090311304Abstract: The invention relates to a drug-loaded implant having a carrier body (10) and at least one drug for delivery into a delivery region. The drug is provided for chemotherapy and/or palliative treatment and can be released topically and/or regionally in a controlled manner at a predefinable rate and/or over a predefinable period of time in the intended active state of the implant.Type: ApplicationFiled: June 11, 2009Publication date: December 17, 2009Inventors: Alexander Borck, Tobias Diener, Claus Harder, Michael Tittelbach, Amir Fargahi
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Publication number: 20090030507Abstract: A stent comprising a degradable metal stent main body; a partition layer which is applied to the surface of the stent main body so that at least parts of the surface of the luminal side are not covered; and an agent-containing layer which is applied to the surface of the partition layer at least partially on the abluminal side of the stent main body and comprises one or more agents and possibly one or more polymers.Type: ApplicationFiled: July 24, 2008Publication date: January 29, 2009Applicant: BIOTRONIK VI PATENT AGInventors: Bjoern Klocke, Tobias Diener, Matthias Fringes, Claus Harder
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Publication number: 20090024210Abstract: A method for producing an agent depot for mechanical connection to a surface of an endovascular implantable body, comprising a) providing one or more polymers; b) providing one or more agents; and c) producing an agent depot from said polymers and said agents, the agent depot being mechanically connectable to the surface of the body using force action or adhesive.Type: ApplicationFiled: July 21, 2008Publication date: January 22, 2009Applicant: Biotronik VI Patent AGInventors: Bjoern Klocke, Tobias Diener, Matthias Fringes, Claus Harder
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Publication number: 20080188927Abstract: The invention concerns an endovascular implant, in particular a stent, with an at least portion-wise active coating. The object of the present invention is to provide locally therapeutic formulations for the treatment of stenosis or restenosis. The implants modified in accordance with the invention are to ensure improved compatibility, in particular in regard to any inflammatory and proliferative processes in the tissue environment. That is achieved in that the active coating includes, as an active substance: 1) PPAR?-agonists, PPAR?-agonists or a combination thereof; 2) an RXR-agonist; or 3) a combination of PPAR-agonists and RXR-agonists.Type: ApplicationFiled: December 6, 2007Publication date: August 7, 2008Applicant: BIOTRONIK MESS- UND THERAPIEGERAETE GMBH & CO.Inventors: Roland Rohde, Katrin Sternberg, Tobias Diener
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Publication number: 20080032946Abstract: A method for producing a composite made of oligonucleotides or polynucleotides and hydrophobic biodegradable polymers. The method comprises the following steps: (i) producing an aqueous solution of a polyethylene glycol having a mean molecular weight in the range from 600 to 8,000 g/mole; (ii) adding an aqueous, possibly buffered solution of oligonucleotides or polynucleotides to the aqueous solution from step (i); iii) freezing the aqueous solution from step (ii) and subsequently freeze-drying the frozen solution to obtain a freeze-dried substrate; (iv) providing a solution of the hydrophobic biodegradable polymer in an organic solvent; (v) adding the substrate obtained according to step (iii) to the solution of the polymer; and (vi) removing the organic solvent to obtain the composite. Also disclosed is a composite produced by the method.Type: ApplicationFiled: July 31, 2007Publication date: February 7, 2008Applicant: BIOTRONIK VI PATENT AGInventors: Alexander Borck, Tobias Diener
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Publication number: 20080008735Abstract: A method for manufacturing a stationary state of polymer crystallinity of an active substance charged polylactide matrix for a stent, comprising the steps of: preparing the active substance charged polylactide matrix containing (a) a polylactide in amorphous or semicrystalline modification or with amorphous domains, and (b) at least one active substance on a surface or in a cavity of the stent communicating with the surface; and beating of the active substance charged polylactide matrix to a temperature ranging from TG?20° C. to TS?10° C., where TG represents a glass transition temperature and TS a melting temperature of the crystallites of the polylactide.Type: ApplicationFiled: July 7, 2006Publication date: January 10, 2008Inventor: Tobias Diener
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Publication number: 20040073297Abstract: The invention concerns an endovascular implant, in particular a stent, with an at least portion-wise active coating. The object of the present invention is to provide locally therapeutic formulations for the treatment of stenosis or restenosis. The implants modified in accordance with the invention are to ensure improved compatibility, in particular in regard to any inflammatory and proliferative processes in the tissue environment. That is achieved in that the active coating includes, as an active substance: 1) PPAR&agr;-agonists, PPAR&dgr;-agonists or a combination thereof; 2) an RXR-agonist; or 3) a combination of PPAR-agonists and RXR-agonists.Type: ApplicationFiled: August 11, 2003Publication date: April 15, 2004Applicant: Biotronik Mess-und Therapiegeraete GmbH & Co.Inventors: Roland Rohde, Katrin Sternberg, Tobias Diener