Patents by Inventor Tobias Heckel

Tobias Heckel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250244054
    Abstract: A test chamber and a method for conditioning air in a temperature-insulated test space of the test chamber, the test space being sealable and configured to receive test materials, a cooling element of a temperature-control device of the test chamber, a first cooling circuit having a first refrigerant, a heat exchanger in the test space, a compressor, a gas cooler, a cascade heat exchanger and an expansion valve yielding a temperature ranging from ?20° C. to +150° C. within the test space, the cascade heat exchanger being connected to a high-pressure side of the first cooling circuit, the cascade heat exchanger being coupled with a second cooling circuit of the cooling element, the temperature in the test space being controlled and/or regulated by a control device of the test chamber. The first refrigerant is an unfluorinated refrigerant and the second cooling circuit comprising a pump and a liquid as a heat carrier.
    Type: Application
    Filed: January 23, 2025
    Publication date: July 31, 2025
    Inventors: Johannes Teichmann, Tobias Heckele
  • Publication number: 20240370999
    Abstract: A computer-implemented method of adjudicating an imaged lesion, comprising: receiving a diagnostic image showing a lesion; processing the diagnostic image in a machine learning algorithm previously trained to classify the lesion and to propose, based on a lesion class for the lesion, a blood test panel suited to adjudicate the lesion; and outputting the proposed blood test panel to a user.
    Type: Application
    Filed: May 1, 2024
    Publication date: November 7, 2024
    Applicant: Siemens Healthineers AG
    Inventors: Philipp HOELZER, Tobias HECKEL, Stefan ASSMANN, Ayse KARABAYIR, Torbjoern KLATT, Robin GUTSCHE, Sebastian SCHMIDT, Ali KAMEN, Vivek SINGH, Alexander BROST, Matthias SIEBERT, Jonathan SPERL
  • Patent number: 9650629
    Abstract: Disclosed is a process for clonal pre-amplification of a nucleic acid involving the steps of (i) providing a plurality of different nucleic acid molecules (b) attaching adaptor sequences to the 3? ends and 5? ends of the nucleic acid molecules (c) preparing a water in oil emulsion wherein the majority of water droplets comprises one or none member of the plurality of different nucleic acid molecules (d) clonally amplifying the plurality of different nucleic acid molecules. In particular, the different nucleic acid molecules are mRNA molecules.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: May 16, 2017
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Thomas Froehlich, Tobias Heckel
  • Patent number: 8822158
    Abstract: The present invention is directed to method for analyzing multiple nucleic acid molecules of interest comprising in the steps of (i) providing a plurality of beads, characterized in that each bead comprises at least two sequence specific amplification primers, further characterized in that at least one of the primers is bound to the bead via a cleavable linker, (ii) capturing the nucleic acid molecules of interest from a sample, (iii) clonally isolating the plurality of beads, (iv) cleaving the at least one primer, (v) clonally amplifying the nucleic acid thereby creating multiple amplification products, and (vi) analyzing the amplification products.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: September 2, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Thomas Froehlich, Dieter Heindl, Angelika Roesler, Tobias Heckel
  • Publication number: 20120010086
    Abstract: Disclosed is a process for clonal pre-amplification of a nucleic acid involving the steps of (i) providing a plurality of different nucleic acid molecules (b) attaching adaptor sequences to the 3? ends and 5? ends of the nucleic acid molecules (c) preparing a water in oil emulsion wherein the majority of water droplets comprises one or none member of the plurality of different nucleic acid molecules (d) clonally amplifying the plurality of different nucleic acid molecules. In particular, the different nucleic acid molecules are mRNA molecules.
    Type: Application
    Filed: June 27, 2011
    Publication date: January 12, 2012
    Inventors: Thomas Froehlich, Tobias Heckel